| Herb ID: H0402 | Chinese Character: 沙苑子 | 
| English Name: Flatstem milkvetch seed | Latin Name: Semen astragali complanati | 
| Chinese Pin Yin : Sha Yuan Zi | TCM-ID: TCMH1811 | 
| Therapeutic Function in Chinese : 补虚 | Therapeutic Function in English: For tonifying weakness | 
| Herb Function: Benefit the liver and the kidney, arrest seminal discharge, restrain urination and improve eyesight | |
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence | 
|---|---|---|---|---|
| T61J7T | Mothers against decapentaplegic homolog 2 | SMAD2 | Q15796 | 1 Reference(s) | 
| T78O6C | Mothers against decapentaplegic homolog 3 | SMAD3 | P84022 | 1 Reference(s) | 
| T15I0F | Proteasome activator complex subunit 1 | PSME1 | Q06323 | 1 Reference(s) | 
| T44BWE | Adiponectin receptor protein 2 | ADIPOR2 | Q86V24 | 1 Reference(s) | 
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY | P01303 | 1 Reference(s) | 
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA | Q07869 | 2 Reference(s) | 
| T08U92 | Mitochondrial brown fat uncoupling protein 1 | UCP1 | P25874 | 1 Reference(s) | 
| T13WH4 | Interferon-induced, double-stranded RNA-activated protein kinase | EIF2AK2 | P19525 | 1 Reference(s) | 
| T77M4W | Adenosine receptor A2a | ADORA2A | P29274 | 1 Reference(s) | 
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG | P37231 | 1 Reference(s) | 
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 | P08183 | 1 Reference(s) | 
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A | Q16665 | 1 Reference(s) | 
| T40G6B | Prostaglandin reductase 1 | PTGR1 | Q14914 | 1 Reference(s) | 
| T27S6H | Pulmonary surfactant-associated protein B | SFTPB | P07988 | 1 Reference(s) | 
| T72BXP | Platelet endothelial cell adhesion molecule | PECAM1 | P16284 | 1 Reference(s) | 
| T86ROZ | Heme oxygenase 1 | HMOX1 | P09601 | 1 Reference(s) | 
| T04MBA | Vascular endothelial growth factor receptor 2 | KDR | P35968 | 1 Reference(s) | 
| T19BO9 | Bone morphogenetic protein 4 | BMP4 | P12644 | 1 Reference(s) | 
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 | P05362 | 1 Reference(s) | 
| T34AW3 | Lipopolysaccharide-binding protein | LBP | P18428 | 1 Reference(s) | 
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 | P10415 | 1 Reference(s) | 
| T82JWE | Cellular tumor antigen p53 | TP53 | P04637 | 1 Reference(s) | 
| T85U8U | Caspase-3 | CASP3 | P42574 | 1 Reference(s) | 
| T23P74 | Caspase-9 | CASP9 | P55211 | 1 Reference(s) | 
| T80TUC | Apoptosis regulator BAX | BAX | Q07812 | 2 Reference(s) | 
| T64BTV | Interleukin-1 beta | IL1B | P01584 | 2 Reference(s) | 
| T30VNV | Myeloperoxidase | MPO | P05164 | 1 Reference(s) | 
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 | P19838 | 1 Reference(s) | 
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 | P40763 | 1 Reference(s) | 
| T23VMI | Tumor necrosis factor | TNF | P01375 | 1 Reference(s) | 
 
                     
                     
                     
                    