Target Description
| Type | Detail |
|---|---|
| Target ID | T36I66 |
| Protein Name | Metallothionein-2 |
| Uniprot ID |
P02795 |
| Protein Name Alias | MT-2; Metallothionein-2A; Metallothionein-II; MT-II |
| Gene ID |
4502 |
| Gene Symbol | MT2A |
| Gene Alias | CES1; MT2 |
| TTD | T53251: Preclinical target |
| Pfam | PF00131 |
| GO |
0036018:cellular response to erythropoietin
0005634:nucleus 0071276:cellular response to cadmium ion 0071280:cellular response to copper ion 0036016:cellular response to interleukin-3 0010273:detoxification of copper ion 0046872:metal ion binding 0060333:interferon-gamma-mediated signaling pathway 0005829:cytosol 0071294:cellular response to zinc ion 0005737:cytoplasm 0010038:response to metal ion 0008270:zinc ion binding 0045926:negative regulation of growth 0006882:cellular zinc ion homeostasis 0006878:cellular copper ion homeostasis |
| PDB | 2MHU ; 1MHU |
| Drugbank | DB00958 ; DB14533 ; DB14487 ; DB01593 ; DB14548 ; DB00515 ; DB12965 ; DB00526 ; DB09130 |
| KEGG | hsa:4502 |
Related Compounds (Total: 5)
C0004
Name: Delphinidin
C0419
Name: Styrene
C0846
Name: Acetaldehyde
C0937
Name: rottlerin
C1278
Name: Daidzein
Related Herbs (Total: 87)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0809 | Zhi Mu | 知母 | Common anemarrhena | Anemarrhena asphodeloides |
| H0246 | Mi Ma Huang | 蜜麻黄 | Ephedra equisetin | Ephedra sinica |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H1021 | E Da Xia | 莪大夏 | NA | Oxytropis falcata |
| H0198 | Ma Huang Gao | 麻黄膏 | Chinese ephedra | Ephedra sinica |
| H0002 | Hui Xiang | 茴香 | Fennel fruit | Foeniculum vulgare |
| H0790 | Zhang Shu Zi | 樟树子 | Camphor tree | Cinnamomum camphora |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0200 | Ma Huang Gen | 麻黄根 | Chinese ephedra root | Ephedra sinica |
| H0018 | Ji Xue Teng Gan Gao | 鸡血藤干膏 | Suberect spatholobus stem | Spatholobus suberectus |
| H0026 | Jiang | 姜 | Soybean paste | Glycine max |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1249 | Huang Qi Jin Gao | 黄芪浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H0897 | Chuan Lian | 川楝 | Chinaberry | Melia azedarach |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H1095 | Ge Gen Gan Jin Gao | 葛根干浸膏 | Lobed kudzuvine root | Pueraria lobata |
| H0944 | Dan Dou Gu | 淡豆鼓 | NA | Glycine max |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0952 | Dan Xiang Chi | 淡香豉 | NA | Glycine max |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0367 | Rou Gui Ye | 肉桂叶 | Cassia bark oil | Oleum cinnamomi |
| H1247 | Huang Qi | 黄芪 | Membranous milkvetch | Astragalus membranaceus |
| H0747 | An Xi Xiang | 安息香 | Sumatra snowbel | Styrax benzoin |
| H0788 | Zhang Nao Zi | 樟脑子 | Camphorar | Cinnamomum camphora |
| H0109 | Ku Lian Zi | 苦楝子 | NA | Melia azedarach |
| H0289 | Niu Bang Zi | 牛蒡子 | Great burdock fruit | Arctium lappa |
| H0368 | Rou Gui Zi | 肉桂子 | Cassiabarktree | Cinnamomum cassia |
| H0201 | Ma Huang Jin Gao | 麻黄浸膏 | Chinese ephedra | Ephedra sinica |
| H1094 | Ge Gen | 葛根 | Lobed kudzuvine root | Pueraria lobata |
| H0670 | Chai Pi Zhang | 豺皮樟 | Oblong-leaved litsea | Litsea rotundifolia |
| H0060 | Jin Si Ku Lian | 金丝苦楝 | NA | Cardiospermum halicacabum |
| H0031 | Jiang Tan | 姜炭 | Soybean paste | Glycine max |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0278 | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 | Indigowoad root | Baphicacanthus cusia |
| H0077 | Jiu | 酒 | Ethanol | Vinum |
| H0366 | Rou Gui | 肉桂 | Cassiabarktree | Cinnamomum cassia |
| H0427 | Shan Zhu Yu | 山茱萸 | Asiatic cornelian cherry | Cornus officinalis |
| H1096 | Ge Hua | 葛花 | flower bud of lobed kudzuvine | Pueraria lobata |
| H0786 | Zhang Mu | 樟木 | Ligum cinmamomi camphorae | Cinnamomum camphora |
| H0405 | Shan Dou Gen | 山豆根 | Tonkin sophora root | Sophora subprostrata |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H1248 | Huang Qi Gan Jin Gao | 黄芪干浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H1007 | Dou You | 豆油 | Soybean oil | Glycine max |
| H0019 | Ji Xue Teng Gao | 鸡血藤膏 | Suberect spatholobus stem | Spatholobus suberectus |
| H1214 | Hua Jiao | 花椒 | Bunge pricklyash | Zanthoxylum bungeanum |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0085 | Jiu Yu Rou | 酒萸肉 | Asiatic cornelian cherry | Cornus officinalis |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0903 | Ci Cai | 荠菜 | Shepherdspurse | Capsella bursa-pastoris |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0108 | Ku Lian Pi | 苦楝皮 | Chinaberry-tree bark | Melia azedarach |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H1173 | Hei Chou | 黑丑 | Pharbitis seed | Semen pharbitidis |
| H1174 | Hei Da Dou | 黑大豆 | Black soyabean | Glycine max |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0277 | Nan Ban Lan Gen | 南板蓝根 | Indigowoad root | Baphicacanthus cusia |
| H0510 | Su He Xiang | 苏合香 | Oriental sweetgum resin | Liquidambar orientalis |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1152 | Bai Jie Zi | 白芥子 | White mustard seed | Sinapis alba |
| H0197 | Ma Huang | 麻黄 | Chinese ephedra | Ephedra sinica |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0981 | Dian Ji Xue Teng Gao Fen | 滇鸡血藤膏粉 | Suberect spatholobus stem | Spatholobus suberectus |
| H1114 | Guan Gui | 官桂 | Cassiabarktree | Cinnamomum cassia |
| H1022 | E Zhu | 莪术 | Zedoray rhizome | Curcuma aeruginosa |
| H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
| H0027 | Jiang Gao | 姜膏 | Soybean paste | Glycine max |
| H0705 | Yan Hu Lu Ba | 盐胡芦巴 | Fenugreek | Trigonella foenum-graecum |
| H1250 | Huang Qi Ti Qu Ye | 黄芪提取液 | Membranous milkvetch | Astragalus membranaceus |
| H1129 | Guang Xi E Zhu | 广西莪术 | rhizome of kwangsi turmeric | Rhizoma curcumae |
| H0307 | Peng E Zhu | 蓬莪术 | Zedoray rhizome | Rhizoma curcumae |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1139 | Gui Zhi | 桂枝 | Cassiabarktree twig | Cinnamomum cassia |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H0565 | Tu Bie Chong | 土鳖虫 | Cockroach | Eupolyphaga sinensis |
| H0787 | Zhang Nao | 樟脑 | Camphorar | Cinnamomum camphora |
| H0789 | Zhang Shu Gen | 樟树根 | Camphor tree | Cinnamomum camphora |
| H1011 | Bai Chou | 白丑 | Pharbitis seed | Semen pharbitidis |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1080 | Gan Ge | 干葛 | Lobed kudzuvine root | Pueraria lobata |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0017 | Ji Xue Teng | 鸡血藤 | Suberect spatholobus stem | Spatholobus suberectus |