| Herb ID: H1022 | Chinese Character: 莪术 | 
| English Name: Zedoray rhizome | Latin Name: Curcuma aeruginosa | 
| Chinese Pin Yin : E Zhu | TCM-ID: TCMH544 | 
| Therapeutic Function in Chinese : 活血化淤 | Therapeutic Function in English: Blood activation and stasis removal | 
| Herb Function: Promote the flow of qi and eliminate blood stasis with strong effect, and relieve pain by removing the stagnation of undigested food | |
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence | 
|---|---|---|---|---|
| T13KGH | Tyrosinase | TYR | 
                                P14679 | 
                            1 Reference(s) | 
| T04H8Y | Beta-secretase 1 | BACE1 | 
                                P56817 | 
                            1 Reference(s) | 
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 | 
                                P18031 | 
                            1 Reference(s) | 
| T26EZU | Myc proto-oncogene protein | MYC | 
                                P01106 | 
                            3 Reference(s) | 
| T85U8U | Caspase-3 | CASP3 | 
                                P42574 | 
                            3 Reference(s) | 
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 | 
                                P27361 | 
                            1 Reference(s) | 
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 | 
                                P28482 | 
                            1 Reference(s) | 
| T05PKX | Steroid 17-alpha-hydroxylase/17,20 lyase | CYP17A1 | 
                                P05093 | 
                            1 Reference(s) | 
| T85S9Z | Cholesterol side-chain cleavage enzyme, mitochondrial | CYP11A1 | 
                                P05108 | 
                            1 Reference(s) | 
| T83YZD | Acetylcholinesterase | ACHE | 
                                P22303 | 
                            1 Reference(s) | 
| T09INZ | Transient receptor potential cation channel subfamily A member 1 | TRPA1 | 
                                O75762 | 
                            1 Reference(s) | 
| T60XJI | Transient receptor potential cation channel subfamily M member 8 | TRPM8 | 
                                Q7Z2W7 | 
                            3 Reference(s) | 
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 | 
                                Q8NER1 | 
                            2 Reference(s) | 
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 | 
                                P19838 | 
                            2 Reference(s) | 
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY | 
                                P01303 | 
                            1 Reference(s) | 
| T95LIF | Cannabinoid receptor 2 | CNR2 | 
                                P34972 | 
                            1 Reference(s) | 
| T70HTD | Cytochrome P450 2E1 | CYP2E1 | 
                                P05181 | 
                            1 Reference(s) | 
| T02QBS | Cytochrome P450 1A2 | CYP1A2 | 
                                P05177 | 
                            1 Reference(s) | 
| T50V79 | Interleukin-4 | IL4 | 
                                P05112 | 
                            2 Reference(s) | 
| T12WTT | Interleukin-5 | IL5 | 
                                P05113 | 
                            2 Reference(s) | 
| T50GQE | Interleukin-13 | IL13 | 
                                P35225 | 
                            1 Reference(s) | 
| T86YQL | Prolactin | PRL | 
                                P01236 | 
                            1 Reference(s) | 
| T32UNL | Lens fiber major intrinsic protein | MIP | 
                                P30301 | 
                            1 Reference(s) | 
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 | 
                                P29474 | 
                            1 Reference(s) | 
| T41INV | Nuclear receptor subfamily 1 group I member 3 | NR1I3 | 
                                Q14994 | 
                            1 Reference(s) | 
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 | 
                                P31749 | 
                            1 Reference(s) | 
| T23VMI | Tumor necrosis factor | TNF | 
                                P01375 | 
                            1 Reference(s) | 
| T64BTV | Interleukin-1 beta | IL1B | 
                                P01584 | 
                            2 Reference(s) | 
| T84W8G | Aryl hydrocarbon receptor | AHR | 
                                P35869 | 
                            2 Reference(s) | 
| T77M4W | Adenosine receptor A2a | ADORA2A | 
                                P29274 | 
                            1 Reference(s) | 
| T13I7C | Transforming growth factor beta-2 proprotein | TGFB2 | 
                                P61812 | 
                            1 Reference(s) | 
| T36I66 | Metallothionein-2 | MT2A | 
                                P02795 | 
                            1 Reference(s) | 
| T45WII | Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide | TGFB3 | 
                                P10600 | 
                            1 Reference(s) | 
| T74I49 | Bcl-2-like protein 1 | BCL2L1 | 
                                Q07817 | 
                            1 Reference(s) | 
| T80TUC | Apoptosis regulator BAX | BAX | 
                                Q07812 | 
                            2 Reference(s) | 
| T85AXP | Cytochrome P450 3A4 | CYP3A4 | 
                                P08684 | 
                            1 Reference(s) | 
| T28DIY | Immunoglobulin heavy constant epsilon | IGHE | 
                                P01854 | 
                            1 Reference(s) | 
| T82I7J | C-C motif chemokine 16 | CCL16 | 
                                O15467 | 
                            1 Reference(s) | 
| T49TDM | Matrix metalloproteinase-9 | MMP9 | 
                                P14780 | 
                            1 Reference(s) | 
| T01QLH | Estrogen receptor | ESR1 | 
                                P03372 | 
                            4 Reference(s) | 
| T89L4V | Insulin | INS | 
                                P01308 | 
                            1 Reference(s) | 
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A | 
                                Q16665 | 
                            1 Reference(s) | 
| T42HHN | Follicle-stimulating hormone receptor | FSHR | 
                                P23945 | 
                            1 Reference(s) | 
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 | 
                                P11168 | 
                            1 Reference(s) | 
| T90ADC | BH3-interacting domain death agonist | BID | 
                                P55957 | 
                            1 Reference(s) | 
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 | 
                                P10415 | 
                            2 Reference(s) | 
| T05O6O | Estrogen receptor beta | ESR2 | 
                                Q92731 | 
                            1 Reference(s) | 
| T09KPZ | Vimentin | VIM | 
                                P08670 | 
                            1 Reference(s) | 
| T30VNV | Myeloperoxidase | MPO | 
                                P05164 | 
                            2 Reference(s) | 
| T82JWE | Cellular tumor antigen p53 | TP53 | 
                                P04637 | 
                            1 Reference(s) | 
| T23P74 | Caspase-9 | CASP9 | 
                                P55211 | 
                            1 Reference(s) | 
| T50VJF | Osteopontin | SPP1 | 
                                P10451 | 
                            1 Reference(s) | 
| T94S85 | Collagen alpha-1(I) chain | COL1A1 | 
                                P02452 | 
                            1 Reference(s) | 
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 | 
                                P35354 | 
                            1 Reference(s) | 
| T09H2Z | Nitric oxide synthase, inducible | NOS2 | 
                                P35228 | 
                            1 Reference(s) | 
| T33OPP | Interleukin-6 | IL6 | 
                                P05231 | 
                            1 Reference(s) |