Target Description

Type Detail
Target ID T13I7C
Protein Name Transforming growth factor beta-2 proprotein
Uniprot ID P61812
Protein Name Alias Cetermin;  Glioblastoma-derived T-cell suppressor factor;  G-TSF
Gene ID 7042
Gene Symbol TGFB2
Gene Alias NA
TTD T14143: Clinical Trial target
Pfam PF00019 ; PF00688
GO
0003179:heart valve morphogenesis

0010862:positive regulation of pathway-restricted SMAD protein phosphorylation

0042476:odontogenesis

0048103:somatic stem cell division

0010629:negative regulation of gene expression

0097191:extrinsic apoptotic signaling pathway

0032147:activation of protein kinase activity

0003289:atrial septum primum morphogenesis

0031069:hair follicle morphogenesis

0005102:signaling receptor binding

0005576:extracellular region

0001942:hair follicle development

1902256:regulation of apoptotic process involved in outflow tract morphogenesis

0034714:type III transforming growth factor beta receptor binding

0010718:positive regulation of epithelial to mesenchymal transition

0005125:cytokine activity

0010634:positive regulation of epithelial cell migration

0042803:protein homodimerization activity

0060412:ventricular septum morphogenesis

0008584:male gonad development

0007179:transforming growth factor beta receptor signaling pathway

0042060:wound healing

0033630:positive regulation of cell adhesion mediated by integrin

0000902:cell morphogenesis

0003148:outflow tract septum morphogenesis

0045778:positive regulation of ossification

0030593:neutrophil chemotaxis

0008347:glial cell migration

0005160:transforming growth factor beta receptor binding

0003203:endocardial cushion morphogenesis

0030097:hemopoiesis

0045747:positive regulation of Notch signaling pathway

0001837:epithelial to mesenchymal transition

1905007:positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

0001666:response to hypoxia

0016477:cell migration

0003274:endocardial cushion fusion

0046580:negative regulation of Ras protein signal transduction

0043025:neuronal cell body

0050714:positive regulation of protein secretion

0060395:SMAD protein signal transduction

0002576:platelet degranulation

0008219:cell death

0008083:growth factor activity

0003184:pulmonary valve morphogenesis

0010936:negative regulation of macrophage cytokine production

0061626:pharyngeal arch artery morphogenesis

0001822:kidney development

0042416:dopamine biosynthetic process

0060038:cardiac muscle cell proliferation

0048839:inner ear development

0008284:positive regulation of cell population proliferation

0045787:positive regulation of cell cycle

0051781:positive regulation of cell division

0001540:amyloid-beta binding

0003149:membranous septum morphogenesis

0042493:response to drug

0030424:axon

0003215:cardiac right ventricle morphogenesis

0032570:response to progesterone

0030199:collagen fibril organization

0007507:heart development

0010002:cardioblast differentiation

0032909:regulation of transforming growth factor beta2 production

0062009:secondary palate development

1903701:substantia propria of cornea development

0007050:cell cycle arrest

0050778:positive regulation of immune response

0045823:positive regulation of heart contraction

0030307:positive regulation of cell growth

0060317:cardiac epithelial to mesenchymal transition

1902895:positive regulation of pri-miRNA transcription by RNA polymerase II

0003181:atrioventricular valve morphogenesis

0031093:platelet alpha granule lumen

0043525:positive regulation of neuron apoptotic process

0009792:embryo development ending in birth or egg hatching

0032874:positive regulation of stress-activated MAPK cascade

0014068:positive regulation of phosphatidylinositol 3-kinase signaling

0030509:BMP signaling pathway

0042127:regulation of cell population proliferation

0051794:regulation of timing of catagen

0008285:negative regulation of cell population proliferation

0051891:positive regulation of cardioblast differentiation

0060413:atrial septum morphogenesis

0060389:pathway-restricted SMAD protein phosphorylation

0005615:extracellular space

0035910:ascending aorta morphogenesis

0003007:heart morphogenesis

0006468:protein phosphorylation

0010693:negative regulation of alkaline phosphatase activity

0048699:generation of neurons

0009611:response to wounding

0001501:skeletal system development

0030308:negative regulation of cell growth

0062023:collagen-containing extracellular matrix

0050680:negative regulation of epithelial cell proliferation

0045216:cell-cell junction organization

0042704:uterine wall breakdown

0003222:ventricular trabecula myocardium morphogenesis

1904888:cranial skeletal system development

0016525:negative regulation of angiogenesis

0060065:uterus development

0007435:salivary gland morphogenesis

0005114:type II transforming growth factor beta receptor binding

0001654:eye development

0003407:neural retina development

0051795:positive regulation of timing of catagen

0001843:neural tube closure

1905006:negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

0048666:neuron development

0030326:embryonic limb morphogenesis

0048566:embryonic digestive tract development

0045726:positive regulation of integrin biosynthetic process

PDB 5TX4 ; 1TFG ; 5TY4 ; 6I9J ; 2TGI ; 4KXZ
Drugbank NA
KEGG hsa:7042

Related Compounds  (Total: 6)

Go to browser
C0041
Name: Emodin
Go to browser
C0101
Name: Genistein
Go to browser
C0325
Name: Progesterone
Go to browser
C0363
Name: Resveratrol
Go to browser
C0419
Name: Styrene


Related Herbs  (Total: 136)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H0088 Ju He橘核 Tangerine seedCitrus reticulata
H1227 Huai Zhi槐枝 NASophora japonica
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0226 Man Yue Mei蔓越莓 CranberryVaccinium oxycoccos
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0201 Ma Huang Jin Gao麻黄浸膏 Chinese ephedraEphedra sinica
H0200 Ma Huang Gen麻黄根 Chinese ephedra rootEphedra sinica
H1033 Fang Ji防己 Fourstamen stephaniaStephania tetrandra
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H0789 Zhang Shu Gen樟树根 Camphor treeCinnamomum camphora
H1114 Guan Gui官桂 CassiabarktreeCinnamomum cassia
H0056 Jin Qiao Mai金荞麦 Wild buckwheat rhizomeRhizoma fagopyri cymosi
H0450 Shi Chang Pu石菖蒲 Grassleaved sweetflagAcorus tatarinowii
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0637 Cha Ye茶叶 Common teaCamellia sinensis
H0357 Ren Shen人参 GinsengPanax ginseng
H1026 Fan Hun Cao返魂草 Tatarian asterAster tataricus
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H1235 Huang Hao黄蒿 Virg ate wormwoodArtemisia scoparia
H1184 Bai Lian白蔹 Japanese ampelopsisAmpelopsis japonica
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1007 Dou You豆油 Soybean oilGlycine max
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0853 Zi Wan紫菀 Tatarion asterAster tataricus
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H1166 He Shou Wu何首乌 Tuber fleeceflowerPolygonum multiflorum
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0452 Shi Chang Pu Qing Gao石菖蒲清膏 Grassleaved sweetflagAcorus tatarinowii
H1029 Fang Er Cha方儿茶 khair in hindiSenegalia catechu
H1222 Huai Hua槐花 flower bud of japanese pagodatreeSophora japonica
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0615 Wu Zhi Mao Tao五指毛桃 five-finger fig rootFicus simplicissima
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1224 Huai Jiao槐角 pod of japanese pagodatreeSophora japonica
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0617 Qian Cao Teng茜草藤 NARubia cordifolia
H0792 Zhang Yu章鱼 Common atlantic octopusOctopus vulgaris
H0979 Di Yu地榆 Garden burnetSanguisorba officinalis
H0129 Le Xian Cai勒苋菜 NAAmaranthus spinosus
H0085 Jiu Yu Rou酒萸肉 Asiatic cornelian cherryCornus officinalis
H1100 Gu Jing Cao谷精草 PipewartEriocaulon buergerianum
H1208 Hu Ma Ren胡麻仁 white seed of oriental sesameSesamum indicum
H0903 Ci Cai荠菜 ShepherdspurseCapsella bursa-pastoris
H1129 Guang Xi E Zhu广西莪术 rhizome of kwangsi turmericRhizoma curcumae
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H0416 Shan Shen山参 NAPanax ginseng
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0747 An Xi Xiang安息香 Sumatra snowbelStyrax benzoin
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0788 Zhang Nao Zi樟脑子 CamphorarCinnamomum camphora
H0026 Jiang Soybean pasteGlycine max
H0110 Ku Mu苦木 Indian quassiawoodPicrasma quassioides
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0533 Teng Ku Shen藤苦参 NASophora flavescens
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H1004 Bai Cha白茶 White teaCamellia sinensis
H0368 Rou Gui Zi肉桂子 CassiabarktreeCinnamomum cassia
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H0434 She Pu Tao蛇葡萄 AmpelopsisAmpelopsis brevipedunculata
H0002 Hui Xiang茴香 Fennel fruitFoeniculum vulgare
H0852 Zi Tan紫檀 Burmacoast padaukPterocarpus indicus
H0198 Ma Huang Gao麻黄膏 Chinese ephedraEphedra sinica
H0790 Zhang Shu Zi樟树子 Camphor treeCinnamomum camphora
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H1223 Huai Hun Cao还魂草 NAAster tataricus
H0307 Peng E Zhu蓬莪术 Zedoray rhizomeRhizoma curcumae
H0270 Mu Hu Die木蝴蝶 Indian trumpetflowerOroxylum indicum
H0432 She Gan射干 BlackberrylilyBelamcanda chinensis
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0809 Zhi Mu知母 Common anemarrhenaAnemarrhena asphodeloides
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0510 Su He Xiang苏合香 Oriental sweetgum resinLiquidambar orientalis
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H1000 Dong Gua Zi冬瓜子 Chinese waxgourd seedBenincasa hispida
H0093 Ju Pi橘皮 Tangerine pericarpCitrus reticulata
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0998 Dong Gua Pi冬瓜皮 Chinese waxgourd peelBenincasa hispida
H0565 Tu Bie Chong土鳖虫 CockroachEupolyphaga sinensis
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0786 Zhang Mu樟木 Ligum cinmamomi camphoraeCinnamomum camphora
H0787 Zhang Nao樟脑 CamphorarCinnamomum camphora
H0341 Qing Feng Teng青风藤 OrientvineSinomenium acutum
H0451 Shi Chang Pu Jin Gao石菖蒲浸膏 Grassleaved sweetflagAcorus tatarinowii
H0980 Di Yu Tan地榆炭 Garden burnetSanguisorba officinalis
H0689 Xue Feng Teng血风藤 NAVentilago leiocarpa
H0575 Tu Ku Shen土苦参 all-grass of hooker wingheadSophora flavescens
H0087 Ju Gu Ye枸骨叶 FOLIUM iLICIS cORNUTAEIlex cornuta
H1213 Hu Zhang虎杖 Japanese fleeceflowerPolygonum cuspidatum
H1225 Huai Mi槐米 NASophora japonica
H0472 Shu Da Huang熟大黄 NARheum palmatum
H1212 Hu Ye Gan Jin Gao槲叶干浸膏 NAQuercus dentata
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0626 Xi Nan Huang Qin西南黄芩 Yunnan skullcapScutellaria amoena
H0883 Chuan She Gan川射干 BlackberrylilyBelamcanda chinensis
H1181 Hei Zhi Ma黑芝麻 Oriental sesameSesamum indicum
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H1011 Bai Chou白丑 Pharbitis seedSemen pharbitidis
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0367 Rou Gui Ye肉桂叶 Cassia bark oilOleum cinnamomi
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H0765 Chi Dou赤豆 Assuki beanVigna angularis
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0366 Rou Gui肉桂 CassiabarktreeCinnamomum cassia
H0102 Jue Ming Zi决明子 Sickle senna seedCassia tora
H0540 Tian Ji Huang田基黄 all - grass of japanese st. johnswortGrangea maderaspatana
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0197 Ma Huang麻黄 Chinese ephedraEphedra sinica
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1022 E Zhu莪术 Zedoray rhizomeCurcuma aeruginosa
H1173 Hei Chou黑丑 Pharbitis seedSemen pharbitidis
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H1117 Guan Zhong贯众 Male fern rhizomeDryopteris crassirhizoma
H0427 Shan Zhu Yu山茱萸 Asiatic cornelian cherryCornus officinalis
H0298 Niu Xi Xi牛西西 Patience dockRumex patientia
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0603 Wu Tong Ye Jin Gao梧桐叶浸膏 Parasol treesFirmiana simplex
H0250 Mi Zi Wan蜜紫菀 Tatarian asterAster tataricus
H1139 Gui Zhi桂枝 Cassiabarktree twigCinnamomum cassia
H0906 Ci Wan刺苋 spiny amaranthAmaranthus spinosus
H0246 Mi Ma Huang蜜麻黄 Ephedra equisetinEphedra sinica
H1207 Hu Ma胡麻 white seed of oriental sesameSesamum indicum
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis