Target Description

Type Detail
Target ID T22JG3
Protein Name Fibroblast growth factor receptor 2
Uniprot ID P21802
Protein Name Alias FGFR-2;  EC 2.7.10.1;  K-sam;  KGFR;  Keratinocyte growth factor receptor;  CD antigen CD332
Gene ID 2263
Gene Symbol FGFR2
Gene Alias BEK;  KGFR;  KSAM
TTD T58454: Successful target
Pfam PF07679 ; PF18123 ; PF07714
GO
0042476:odontogenesis

0060501:positive regulation of epithelial cell proliferation involved in lung morphogenesis

0009986:cell surface

0016021:integral component of membrane

0048608:reproductive structure development

0031069:hair follicle morphogenesis

0001525:angiogenesis

0060463:lung lobe morphogenesis

0035603:fibroblast growth factor receptor signaling pathway involved in hemopoiesis

0046777:protein autophosphorylation

0005576:extracellular region

0035604:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow

0033674:positive regulation of kinase activity

0060595:fibroblast growth factor receptor signaling pathway involved in mammary gland specification

0033688:regulation of osteoblast proliferation

0030324:lung development

0060045:positive regulation of cardiac muscle cell proliferation

0060667:branch elongation involved in salivary gland morphogenesis

0021769:orbitofrontal cortex development

0010518:positive regulation of phospholipase activity

0030177:positive regulation of Wnt signaling pathway

0042803:protein homodimerization activity

0042060:wound healing

0003148:outflow tract septum morphogenesis

0002053:positive regulation of mesenchymal cell proliferation

0060915:mesenchymal cell differentiation involved in lung development

0045471:response to ethanol

0071300:cellular response to retinoic acid

0004713:protein tyrosine kinase activity

0043410:positive regulation of MAPK cascade

0060916:mesenchymal cell proliferation involved in lung development

0050679:positive regulation of epithelial cell proliferation

0005524:ATP binding

0001837:epithelial to mesenchymal transition

0008589:regulation of smoothened signaling pathway

0003416:endochondral bone growth

0007409:axonogenesis

0060529:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development

0060076:excitatory synapse

0060348:bone development

0060664:epithelial cell proliferation involved in salivary gland morphogenesis

0060527:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

0042802:identical protein binding

0060512:prostate gland morphogenesis

0060174:limb bud formation

0006915:apoptotic process

0030901:midbrain development

0030282:bone mineralization

0045165:cell fate commitment

0030855:epithelial cell differentiation

0005938:cell cortex

0030916:otic vesicle formation

0008284:positive regulation of cell population proliferation

0045787:positive regulation of cell cycle

0071560:cellular response to transforming growth factor beta stimulus

0048286:lung alveolus development

0005007:fibroblast growth factor-activated receptor activity

0051781:positive regulation of cell division

0000122:negative regulation of transcription by RNA polymerase II

0051897:positive regulation of protein kinase B signaling

0048730:epidermis morphogenesis

0090263:positive regulation of canonical Wnt signaling pathway

0045667:regulation of osteoblast differentiation

0048705:skeletal system morphogenesis

0021847:ventricular zone neuroblast division

0032808:lacrimal gland development

0000165:MAPK cascade

0048701:embryonic cranial skeleton morphogenesis

0003149:membranous septum morphogenesis

0016020:membrane

0009880:embryonic pattern specification

0032496:response to lipopolysaccharide

0035607:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development

0060349:bone morphogenesis

0021860:pyramidal neuron development

0060445:branching involved in salivary gland morphogenesis

0010839:negative regulation of keratinocyte proliferation

0017134:fibroblast growth factor binding

0048565:digestive tract development

0022612:gland morphogenesis

0005886:plasma membrane

0060688:regulation of morphogenesis of a branching structure

0048661:positive regulation of smooth muscle cell proliferation

0016331:morphogenesis of embryonic epithelium

0048762:mesenchymal cell differentiation

0055010:ventricular cardiac muscle tissue morphogenesis

0045944:positive regulation of transcription by RNA polymerase II

0005634:nucleus

0008543:fibroblast growth factor receptor signaling pathway

0070372:regulation of ERK1 and ERK2 cascade

0060601:lateral sprouting from an epithelium

0035602:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell

0060442:branching involved in prostate gland morphogenesis

0008201:heparin binding

0060484:lung-associated mesenchyme development

0048568:embryonic organ development

0060523:prostate epithelial cord elongation

0048755:branching morphogenesis of a nerve

0018108:peptidyl-tyrosine phosphorylation

0007169:transmembrane receptor protein tyrosine kinase signaling pathway

0060449:bud elongation involved in lung branching

0042472:inner ear morphogenesis

0009791:post-embryonic development

0007275:multicellular organism development

0001657:ureteric bud development

0048557:embryonic digestive tract morphogenesis

0005794:Golgi apparatus

0007267:cell-cell signaling

0048333:mesodermal cell differentiation

0001701:in utero embryonic development

0060670:branching involved in labyrinthine layer morphogenesis

0060615:mammary gland bud formation

0005887:integral component of plasma membrane

0051150:regulation of smooth muscle cell differentiation

0005737:cytoplasm

0043235:receptor complex

0070374:positive regulation of ERK1 and ERK2 cascade

0009887:animal organ morphogenesis

0048562:embryonic organ morphogenesis

0035265:organ growth

0004714:transmembrane receptor protein tyrosine kinase activity

0031410:cytoplasmic vesicle

PDB 2PVF ; 4J98 ; 1NUN ; 1II4 ; 2PVY ; 2PY3 ; 6LVL ; 6LVK ; 1WVZ ; 5UGX ; 6AGX ; 1OEC ; 4J96 ; 1GJO ; 4WV1 ; 6V6Q ; 2PZR ; 5UGL ; 2FDB ; 1EV2 ; 4J99 ; 3EUU ; 1E0O ; 5UHN ; 2PZ5 ; 4J97 ; 3B2T ; 3CU1 ; 5UI0 ; 1DJS ; 2PZP ; 3CAF ; 3OJ2 ; 2Q0B ; 3DAR ; 3CLY ; 5EG3 ; 2PSQ ; 2PWL ; 1IIL ; 4J23 ; 3OJM ; 4J95 ; 3RI1
Drugbank DB12010 ; DB15822 ; DB15685 ; DB00039 ; DB12147 ; DB01109 ; DB15102 ; DB02058 ; DB02491 ; DB08901 ; DB08896 ; DB09078 ; DB10770 ; DB01901 ; DB09079 ; DB01041 ; DB10772
KEGG hsa:2263

Related Compounds  (Total: 3)

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C0055
Name: Estradiol
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C0083
Name: Formononetin
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C0325
Name: Progesterone


Related Herbs  (Total: 68)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1248 Huang Qi Gan Jin Gao黄芪干浸膏 Membranous milkvetchAstragalus membranaceus
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
H0077 Jiu EthanolVinum
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0377 San Ling三棱 Common burreedSparganium stoloniferum
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0198 Ma Huang Gao麻黄膏 Chinese ephedraEphedra sinica
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0278 Nan Ban Lan Gen Jin Gao Fen南板蓝根浸膏粉 Indigowoad rootBaphicacanthus cusia
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0520 Tai Pan Fen胎盘粉 Fetus powderHuman placenta
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H0437 She Xiang麝香 AbelmuskMoschus moschiferus
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H1152 Bai Jie Zi白芥子 White mustard seedSinapis alba
H0236 Mao She Xiang Jin Gao毛麝香浸膏 AbelmuskMoschus moschiferus
H0705 Yan Hu Lu Ba盐胡芦巴 FenugreekTrigonella foenum-graecum
H0152 Ling Zhi Jin Gao灵芝浸膏 NAGanoderma lucidum
H0197 Ma Huang麻黄 Chinese ephedraEphedra sinica
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H0200 Ma Huang Gen麻黄根 Chinese ephedra rootEphedra sinica
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1250 Huang Qi Ti Qu Ye黄芪提取液 Membranous milkvetchAstragalus membranaceus
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0575 Tu Ku Shen土苦参 all-grass of hooker wingheadSophora flavescens
H0826 Chu Mu Dan臭牡丹 rose glorybowerClerodendrum bungei
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0356 Ren Gong She Xiang人工麝香 AbelmuskMoschus moschiferus
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0214 Bei He Huan北合欢 AlbiziaAlbizia julibrissin
H1249 Huang Qi Jin Gao黄芪浸膏 Membranous milkvetchAstragalus membranaceus
H0153 Ling Zhi(1)灵芝 Lucid ganodermaGanoderma lucidum
H0235 Mao She Xiang毛麝香 AbelmuskMoschus moschiferus
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0533 Teng Ku Shen藤苦参 NASophora flavescens
H0277 Nan Ban Lan Gen南板蓝根 Indigowoad rootBaphicacanthus cusia
H1202 Hu Huang Lian胡黄连 PicrorhizaPicrorhiza kurrooa
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1021 E Da Xia莪大夏 NAOxytropis falcata
H0201 Ma Huang Jin Gao麻黄浸膏 Chinese ephedraEphedra sinica
H0957 Dang Gui Teng当归藤 NAEmbelia parviflora
H0661 Xiao Hei Dou小黑豆 Black turtle beanPhaseolus vulgaris
H1247 Huang Qi黄芪 Membranous milkvetchAstragalus membranaceus
H0246 Mi Ma Huang蜜麻黄 Ephedra equisetinEphedra sinica
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis