Herb Description

Herb ID:   H0377 Chinese Character:   三棱
English Name:  Common burreed Latin Name:  Sparganium stoloniferum
Chinese Pin Yin :  San Ling TCM-ID:  TCMH1766
Therapeutic Function in Chinese :  活血化淤 Therapeutic Function in English:  Blood activation and stasis removal
Herb Function:  Eliminate blood stasis with strong effect, promote the flow of qi, remove the retention of undigested food, and relieve pain

Related Targets  (Total: 98)

Target idProtein NameGene SymbolUniprot IDNo.of Literature Evidence
T02QBS Cytochrome P450 1A2CYP1A2 P05177
1 Reference(s)
T69XVX Cytochrome P450 1B1CYP1B1 Q16678
1 Reference(s)
T80OJF Interstitial collagenaseMMP1 P03956
2 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
4 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
5 Reference(s)
T63BQU Cytochrome P450 1A1CYP1A1 P04798
1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
4 Reference(s)
T84W8G Aryl hydrocarbon receptorAHR P35869
2 Reference(s)
T14JSQ Baculoviral IAP repeat-containing protein 2BIRC2 Q13490
1 Reference(s)
T70YKV Baculoviral IAP repeat-containing protein 3BIRC3 Q13489
1 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
2 Reference(s)
T40B7E Calcium uniporter protein, mitochondrialMCU Q8NE86
1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
1 Reference(s)
T13KGH TyrosinaseTYR P14679
2 Reference(s)
T31MUM 5,6-dihydroxyindole-2-carboxylic acid oxidaseTYRP1 P17643
1 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
1 Reference(s)
T23P74 Caspase-9CASP9 P55211
3 Reference(s)
T85U8U Caspase-3CASP3 P42574
9 Reference(s)
T50SJ8 5'-AMP-activated protein kinase catalytic subunit alpha-2PRKAA2 P54646
1 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
2 Reference(s)
T25Y64 CholinesteraseBCHE P06276
1 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
1 Reference(s)
T81I4T 5'-AMP-activated protein kinase catalytic subunit alpha-1PRKAA1 Q13131
1 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
1 Reference(s)
T04H8Y Beta-secretase 1BACE1 P56817
2 Reference(s)
T58XLK Tyrosine-protein phosphatase non-receptor type 1PTPN1 P18031
1 Reference(s)
T26EZU Myc proto-oncogene proteinMYC P01106
1 Reference(s)
T05O6O Estrogen receptor betaESR2 Q92731
1 Reference(s)
T22JG3 Fibroblast growth factor receptor 2FGFR2 P21802
1 Reference(s)
T30VNV MyeloperoxidaseMPO P05164
1 Reference(s)
T83DDX Endothelial protein C receptorPROCR Q9UNN8
1 Reference(s)
T06VX0 MAP/microtubule affinity-regulating kinase 4MARK4 Q96L34
1 Reference(s)
T24C0P Bile acid receptorNR1H4 Q96RI1
1 Reference(s)
T77TY2 Protein disulfide-isomeraseP4HB P07237
1 Reference(s)
T20RA0 Adenosine deaminaseADA P00813
1 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
1 Reference(s)
T93SFQ NAD-dependent protein deacetylase sirtuin-1SIRT1 Q96EB6
2 Reference(s)
T92Q77 Type I iodothyronine deiodinaseDIO1 P49895
1 Reference(s)
T67HAF Signal transducer and activator of transcription 1-alpha/betaSTAT1 P42224
1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
3 Reference(s)
T07TMB Cyclin-dependent kinase 1CDK1 P06493
1 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
1 Reference(s)
T48XM4 Glutathione S-transferase Mu 2GSTM2 P28161
1 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
1 Reference(s)
T87WYU Glutathione S-transferase Mu 1GSTM1 P09488
1 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
2 Reference(s)
T10HL8 Intercellular adhesion molecule 1ICAM1 P05362
2 Reference(s)
T29MD1 Mitogen-activated protein kinase 8MAPK8 P45983
2 Reference(s)
T50SX0 Nuclear receptor subfamily 1 group I member 2NR1I2 O75469
1 Reference(s)
T41INV Nuclear receptor subfamily 1 group I member 3NR1I3 Q14994
1 Reference(s)
T59IKQ Vascular cell adhesion protein 1VCAM1 P19320
1 Reference(s)
T24U57 E-selectinSELE P16581
1 Reference(s)
T87DEX Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenaseXDH P47989
1 Reference(s)
T54OSZ PleckstrinPLEK P08567
2 Reference(s)
T63FNY NSFL1 cofactor p47NSFL1C Q9UNZ2
2 Reference(s)
T32UNL Lens fiber major intrinsic proteinMIP P30301
1 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
2 Reference(s)
T22H8P Carbonic anhydrase 3CA3 P07451
1 Reference(s)
T38T1U Caspase-8CASP8 Q14790
1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
3 Reference(s)
T53AOE Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptideTGFB1 P01137
3 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
1 Reference(s)
T89L4V InsulinINS P01308
1 Reference(s)
T21Q0D 3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMGCR P04035
1 Reference(s)
T33OPP Interleukin-6IL6 P05231
2 Reference(s)
T16A2X CatalaseCAT P04040
1 Reference(s)
T64BTV Interleukin-1 betaIL1B P01584
1 Reference(s)
T07VO1 Steroid hormone receptor ERR1ESRRA P11474
2 Reference(s)
T99ARN Forkhead box protein P3FOXP3 Q9BZS1
1 Reference(s)
T18DUA Tight junction protein ZO-1TJP1 Q07157
1 Reference(s)
T71BDH Mitogen-activated protein kinase 14MAPK14 Q16539
2 Reference(s)
T09BRP NAPKB_RS07820 NA
2 Reference(s)
T54CIF Interleukin-8CXCL8 P10145
2 Reference(s)
T10IWJ Bone morphogenetic protein receptor type-2BMPR2 Q13873
1 Reference(s)
T75PC7 NAMIR21 NA
1 Reference(s)
T14DX3 Ribosomal protein S6 kinase alpha-3RPS6KA3 P51812
1 Reference(s)
T66WWM Claudin-2CLDN2 P57739
1 Reference(s)
T14ENF Microtubule-associated protein 2MAP2 P11137
1 Reference(s)
T78ZF2 Protein kinase C alpha typePRKCA P17252
1 Reference(s)
T93VFT Endothelin-1EDN1 P05305
1 Reference(s)
T60UPF Parvalbumin alphaPVALB P20472
2 Reference(s)
T69RXK Cytochrome P450 2C9CYP2C9 P11712
1 Reference(s)
T18CUI Neuron-specific calcium-binding protein hippocalcinHPCA P84074
1 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
1 Reference(s)
T39RV3 Dual specificity mitogen-activated protein kinase kinase 1MAP2K1 Q02750
1 Reference(s)
T66S13 Dual specificity mitogen-activated protein kinase kinase 2MAP2K2 P36507
1 Reference(s)
T08SJX Astrocytic phosphoprotein PEA-15PEA15 Q15121
1 Reference(s)
T38OQ4 Peroxiredoxin-2PRDX2 P32119
1 Reference(s)
T38J3Y Gamma-enolaseENO2 P09104
1 Reference(s)
T82I7J C-C motif chemokine 16CCL16 O15467
1 Reference(s)
T90XMB Ubiquitin carboxyl-terminal hydrolase 5USP5 P45974
1 Reference(s)
T16MRU NACHT, LRR and PYD domains-containing protein 3NLRP3 Q96P20
1 Reference(s)
T40G6B Prostaglandin reductase 1PTGR1 Q14914
1 Reference(s)
T50WOV ATP-dependent translocase ABCB1ABCB1 P08183
1 Reference(s)
T87QUW Actin, aortic smooth muscleACTA2 P62736
1 Reference(s)
T04WT7 FibronectinFN1 P02751
1 Reference(s)
T57HGP Tumor necrosis factor receptor superfamily member 6FAS P25445
1 Reference(s)

Related Compounds  (Total: 9)

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C0164
Name: Kaempferol
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C0291
Name: Paraben
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C0420
Name: Succinic Acid
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C0478
Name: Vanillic Acid
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C1178
Name: Beta-Sitosterol