HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	1 Reference(s)
T69XVX	Cytochrome P450 1B1	CYP1B1	Q16678	1 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	2 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	4 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	5 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	1 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	4 Reference(s)
T84W8G	Aryl hydrocarbon receptor	AHR	P35869	2 Reference(s)
T14JSQ	Baculoviral IAP repeat-containing protein 2	BIRC2	Q13490	1 Reference(s)
T70YKV	Baculoviral IAP repeat-containing protein 3	BIRC3	Q13489	1 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	2 Reference(s)
T40B7E	Calcium uniporter protein, mitochondrial	MCU	Q8NE86	1 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	1 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	2 Reference(s)
T31MUM	5,6-dihydroxyindole-2-carboxylic acid oxidase	TYRP1	P17643	1 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	3 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	9 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T22OPB	Nuclear factor erythroid 2-related factor 2	NFE2L2	Q16236	2 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	1 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	1 Reference(s)
T81I4T	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	Q13131	1 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	1 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	2 Reference(s)
T58XLK	Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	1 Reference(s)
T26EZU	Myc proto-oncogene protein	MYC	P01106	1 Reference(s)
T05O6O	Estrogen receptor beta	ESR2	Q92731	1 Reference(s)
T22JG3	Fibroblast growth factor receptor 2	FGFR2	P21802	1 Reference(s)
T30VNV	Myeloperoxidase	MPO	P05164	1 Reference(s)
T83DDX	Endothelial protein C receptor	PROCR	Q9UNN8	1 Reference(s)
T06VX0	MAP/microtubule affinity-regulating kinase 4	MARK4	Q96L34	1 Reference(s)
T24C0P	Bile acid receptor	NR1H4	Q96RI1	1 Reference(s)
T77TY2	Protein disulfide-isomerase	P4HB	P07237	1 Reference(s)
T20RA0	Adenosine deaminase	ADA	P00813	1 Reference(s)
T74QXI	Serine/threonine-protein kinase mTOR	MTOR	P42345	1 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	2 Reference(s)
T92Q77	Type I iodothyronine deiodinase	DIO1	P49895	1 Reference(s)
T67HAF	Signal transducer and activator of transcription 1-alpha/beta	STAT1	P42224	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	3 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	1 Reference(s)
T86ROZ	Heme oxygenase 1	HMOX1	P09601	1 Reference(s)
T48XM4	Glutathione S-transferase Mu 2	GSTM2	P28161	1 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	1 Reference(s)
T87WYU	Glutathione S-transferase Mu 1	GSTM1	P09488	1 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	2 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	2 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	2 Reference(s)
T50SX0	Nuclear receptor subfamily 1 group I member 2	NR1I2	O75469	1 Reference(s)
T41INV	Nuclear receptor subfamily 1 group I member 3	NR1I3	Q14994	1 Reference(s)
T59IKQ	Vascular cell adhesion protein 1	VCAM1	P19320	1 Reference(s)
T24U57	E-selectin	SELE	P16581	1 Reference(s)
T87DEX	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	XDH	P47989	1 Reference(s)
T54OSZ	Pleckstrin	PLEK	P08567	2 Reference(s)
T63FNY	NSFL1 cofactor p47	NSFL1C	Q9UNZ2	2 Reference(s)
T32UNL	Lens fiber major intrinsic protein	MIP	P30301	1 Reference(s)
T64UH1	Nitric oxide synthase, endothelial	NOS3	P29474	2 Reference(s)
T22H8P	Carbonic anhydrase 3	CA3	P07451	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	3 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	3 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	1 Reference(s)
T89L4V	Insulin	INS	P01308	1 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	2 Reference(s)
T16A2X	Catalase	CAT	P04040	1 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	1 Reference(s)
T07VO1	Steroid hormone receptor ERR1	ESRRA	P11474	2 Reference(s)
T99ARN	Forkhead box protein P3	FOXP3	Q9BZS1	1 Reference(s)
T18DUA	Tight junction protein ZO-1	TJP1	Q07157	1 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	2 Reference(s)
T09BRP	NA	PKB_RS07820	NA	2 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	2 Reference(s)
T10IWJ	Bone morphogenetic protein receptor type-2	BMPR2	Q13873	1 Reference(s)
T75PC7	NA	MIR21	NA	1 Reference(s)
T14DX3	Ribosomal protein S6 kinase alpha-3	RPS6KA3	P51812	1 Reference(s)
T66WWM	Claudin-2	CLDN2	P57739	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T60UPF	Parvalbumin alpha	PVALB	P20472	2 Reference(s)
T69RXK	Cytochrome P450 2C9	CYP2C9	P11712	1 Reference(s)
T18CUI	Neuron-specific calcium-binding protein hippocalcin	HPCA	P84074	1 Reference(s)
T92BZ2	Catenin beta-1	CTNNB1	P35222	1 Reference(s)
T39RV3	Dual specificity mitogen-activated protein kinase kinase 1	MAP2K1	Q02750	1 Reference(s)
T66S13	Dual specificity mitogen-activated protein kinase kinase 2	MAP2K2	P36507	1 Reference(s)
T08SJX	Astrocytic phosphoprotein PEA-15	PEA15	Q15121	1 Reference(s)
T38OQ4	Peroxiredoxin-2	PRDX2	P32119	1 Reference(s)
T38J3Y	Gamma-enolase	ENO2	P09104	1 Reference(s)
T82I7J	C-C motif chemokine 16	CCL16	O15467	1 Reference(s)
T90XMB	Ubiquitin carboxyl-terminal hydrolase 5	USP5	P45974	1 Reference(s)
T16MRU	NACHT, LRR and PYD domains-containing protein 3	NLRP3	Q96P20	1 Reference(s)
T40G6B	Prostaglandin reductase 1	PTGR1	Q14914	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T87QUW	Actin, aortic smooth muscle	ACTA2	P62736	1 Reference(s)
T04WT7	Fibronectin	FN1	P02751	1 Reference(s)
T57HGP	Tumor necrosis factor receptor superfamily member 6	FAS	P25445	1 Reference(s)

Herb ID: H0377	Chinese Character: 三棱
English Name: Common burreed	Latin Name: Sparganium stoloniferum
Chinese Pin Yin : San Ling	TCM-ID: TCMH1766
Therapeutic Function in Chinese : 活血化淤	Therapeutic Function in English: Blood activation and stasis removal
Herb Function: Eliminate blood stasis with strong effect, promote the flow of qi, remove the retention of undigested food, and relieve pain

Herb Description

Related Targets (Total: 98)

Related Compounds (Total: 9)