Compound Description
| ID: C0935 | Common name: Astragalin |
| IUPAC: 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | CAS: CAS:480-10-4 |
| Chembl ID: CHEMBL233930 | Pubchem ID: CID:5282102 |
| Formula: C21H20O11 | TCM-ID: TCMC737 |
| Smiles: OC[C@H]1O[C@@H](Oc2c(oc3c(c2=O)c(O)cc(c3)O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O | |
| Alias:
Astragalin;
3-(β-D-Glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 3-Glucosylkaempferol; 4',5,7-Trihydroxyflavone 3-β-D-glucopyranoside; Astragaline; K 5; Kaemferol 3-O-glucopyranoside; Kaempferol 3-O-glucopyranoside; Kaempferol 3-O-glucoside; Kaempferol 3-O-β-D-glucopyranoside; Kaempferol 3-O-β-D-glucoside; Kaempferol 3-O-β-glucoside; Kaempferol 3-glucoside; Kaempferol 3-β-D-glucopyranoside; Kaempferol 3-β-D-glucoside; Kaempherol 3-O-β-D-glucopyranoside |
Structure:
|
Related Targets (Total: 1)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
A | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 101)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H1150 | Hai Jin Sha Teng Gan Jin Gao | 海金沙藤干浸膏 | NA | Lygodium japonicum |
| H0626 | Xi Nan Huang Qin | 西南黄芩 | Yunnan skullcap | Scutellaria amoena |
| H1090 | Gao Ben | 藁本 | Chinese ligusticum | Ligusticum sinense |
| H0658 | Xiao Fan Tian Hua | 肖梵天花 | Caesarweed | Urena lobata |
| H0002 | Hui Xiang | 茴香 | Fennel fruit | Foeniculum vulgare |
| H0818 | Zhi Zi | 栀子 | Cape jasmine fruit | Gardenia jasminoides |
| H0424 | Shan Zhi | 山栀 | Cape jasmine | Gardenia jasminoides |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0655 | Xiao Bai Bu | 小百部 | Officinal asparagus | Asparagus officinalis |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0115 | Kuan Dong Hua | 款冬花 | Common coltsfoot | Tussilago farfara |
| H0170 | Lu Bian Qing | 路边青 | Manyflower glorybower leaf | Clerodendron cyrtophyllum |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H1249 | Huang Qi Jin Gao | 黄芪浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H0965 | Deng Zhan Xi Xin | 灯盏细辛 | Shortscape fleabane | Erigeron breviscapus |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H0958 | Dang Shen | 党参 | Pilose asiabell | Codonopsis pilosula |
| H0541 | Cang Qie Gen | 藏茄根 | Tibetan eggplant root | Anisodus tanguticus |
| H1124 | Guang Jin Qian Cao | 广金钱草 | Snowbellleaf tickclover | Desmodium styracifolium |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H1009 | Du Huo | 独活 | Doubleteeth pubescent angelica | Angelica pubescens |
| H0057 | Jin Sha Teng | 金沙藤 | NA | Lygodium japonicum |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0693 | Xue Xie | 血蝎 | Dragon's blood | Daemonorops draco |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0868 | Chuan Du Huo | 川独活 | Doubleteeth pubescent angelica | Angelica pubescens |
| H0425 | Shan Zhi Ma | 山芝麻 | Narrowleaf screwtree | Helicteres angustifolia |
| H0045 | Jin Fei Cao | 金沸草 | Japanese inula | Inula japonica |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1247 | Huang Qi | 黄芪 | Membranous milkvetch | Astragalus membranaceus |
| H0120 | Ban Bian Qi | 半边旗 | pinnated brake herb | Pteris semipinnata |
| H1187 | Hong Guan Yao | 红管药 | NA | Aster ageratoides |
| H0696 | Ya Jiao Ai | 鸭脚艾 | Ghostplant wormwood | Artemisia lactiflora |
| H0974 | Di Jin Cao | 地锦草 | Humifuse euphorbia | Euphorbia humifusa |
| H0181 | Luo Bu Ma | 罗布麻 | Dogbane | Apocynum venetum |
| H1147 | Hai Jin Sha | 海金砂 | Japanese climbing fern | Lygodium japonicum |
| H0426 | Shan Zhi Ma Gan Jin Gao | 山芝麻干浸膏 | Narrowleaf screwtree | Helicteres angustifolia |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0413 | Shan Lang Dang | 山莨菪 | NA | Anisodus tanguticus |
| H1188 | Hong Hua | 红花 | Safflower | Carthamus tinctorius |
| H1149 | Hai Jin Sha Teng | 海金沙藤 | NA | Lygodium japonicum |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H1202 | Hu Huang Lian | 胡黄连 | Picrorhiza | Picrorhiza kurrooa |
| H1046 | Feng Xian Tou Gu Cao | 凤仙透骨草 | Spotted snapweed | Impatiens balsamina |
| H0979 | Di Yu | 地榆 | Garden burnet | Sanguisorba officinalis |
| H0243 | Mi Kuan Dong Hua | 蜜款冬花 | Common coltsfoot | Tussilago farfara |
| H0978 | Di Tao Hua | 地桃花 | Rose mallow | Urena lobata |
| H0580 | Tu Si Rou | 菟丝肉 | Dodder seed | Cuscuta australis |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0468 | Shi Wei | 石韦 | Japanese felt fern frond | Pyrrosia lingua |
| H1045 | Feng Xian Hua | 凤仙花 | Spotted snapweed | Impatiens balsamina |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0581 | Tu Si Zi | 菟丝子 | Dodder seed | Cuscuta australis |
| H0411 | Shan Ku Mai | 山苦荬 | China ixeris | Ixeris chinensis |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
| H0015 | Ji Xing Zi | 急性子 | Garden balsam seed | Impatiens balsamina |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1248 | Huang Qi Gan Jin Gao | 黄芪干浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H0656 | Xiao Bo Gen | 小檗根 | Barberry root | Berberis julianae |
| H0237 | Mei Gui Hua | 玫瑰花 | Rugose rose flower | Rosa rugosa |
| H0583 | Tu Si Zi Teng | 菟丝子藤 | Dodder seed | Cuscuta australis |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0730 | Ye Ma Zhui | 野马追 | NA | Eupatorium lindleyanum |
| H0819 | Zhi Zi Jin Gao | 栀子浸膏 | Cape jasmine fruit | Gardenia jasminoides |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0632 | Xia Ku Cao | 夏枯草 | Common selfheal | Prunella vulgaris |
| H0619 | Xi Geng Hu Zhi Zi | 细梗胡枝子 | Lespedeza | Lespedeza virgata |
| H0960 | Dang Shen Qing Gao | 党参清膏 | Root of hairy asiabell | Codonopsis pilosula |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0498 | Si Ji Cai | 四季菜 | Ghostplant wormwood | Artemisia lactiflora |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0104 | Bai Zhu | 白术 | Largehead atractylodes | Atractylodes macrocephala |
| H0379 | Bian Xu | 萹蓄 | Common knotgrass | Polygonum aviculare |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0006 | Bai Qu Cai | 白屈菜 | Greater celandine | Chelidonium majus |
| H0772 | Yue Ji Hua | 月季花 | Chinese rose | Rosa chinensis |
| H0454 | Shi Diao Bai | 石刁柏 | Curinary asparagus | Asparagus officinalis |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H1250 | Huang Qi Ti Qu Ye | 黄芪提取液 | Membranous milkvetch | Astragalus membranaceus |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0975 | Di Mian Cao | 地绵草 | NA | Euphorbia humifusa |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0491 | Shui San Qi | 水三七 | NA | Tacca plantaginea |
| H0158 | Liu Ling Ju | 六棱菊 | NA | Laggera alata |
| H1128 | Bai Jiang | 败酱 | Whiteflower patrinia | Patrinia villosa |
| H0792 | Zhang Yu | 章鱼 | Common atlantic octopus | Octopus vulgaris |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1148 | Hai Jin Sha Cao | 海金沙草 | NA | Lygodium japonicum |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0980 | Di Yu Tan | 地榆炭 | Garden burnet | Sanguisorba officinalis |
Ckey description of the interaction between compound and target