Herb Description

Herb ID:   H0425 Chinese Character:   山芝麻
English Name:  Narrowleaf screwtree Latin Name:  Helicteres angustifolia
Chinese Pin Yin :  Shan Zhi Ma TCM-ID:  TCMH1859
Therapeutic Function in Chinese :  NA Therapeutic Function in English:  NA
Herb Function:  NA

Related Targets  (Total: 256)

Target idProtein NameGene SymbolUniprot IDNo.of Literature Evidence
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
6 Reference(s)
T07VJT Multidrug and toxin extrusion protein 1SLC47A1 Q96FL8
1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
14 Reference(s)
T02QBS Cytochrome P450 1A2CYP1A2 P05177
3 Reference(s)
T69XVX Cytochrome P450 1B1CYP1B1 Q16678
3 Reference(s)
T80OJF Interstitial collagenaseMMP1 P03956
6 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
17 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
15 Reference(s)
T63BQU Cytochrome P450 1A1CYP1A1 P04798
7 Reference(s)
T84W8G Aryl hydrocarbon receptorAHR P35869
4 Reference(s)
T14JSQ Baculoviral IAP repeat-containing protein 2BIRC2 Q13490
1 Reference(s)
T70YKV Baculoviral IAP repeat-containing protein 3BIRC3 Q13489
1 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
3 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
4 Reference(s)
T40B7E Calcium uniporter protein, mitochondrialMCU Q8NE86
1 Reference(s)
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
3 Reference(s)
T77TY2 Protein disulfide-isomeraseP4HB P07237
2 Reference(s)
T43G0N Cytochrome P450 2C8CYP2C8 P10632
1 Reference(s)
T01FVG DNA gyrase subunit BgyrB P0AES6
1 Reference(s)
T73LPO Poly [ADP-ribose] polymerase 1PARP1 P09874
3 Reference(s)
T43N2D Epidermal growth factor receptorEGFR P00533
3 Reference(s)
T38K2W Receptor tyrosine-protein kinase erbB-2ERBB2 P04626
4 Reference(s)
T30VNV MyeloperoxidaseMPO P05164
3 Reference(s)
T67JR8 Heat shock factor protein 1HSF1 Q00613
2 Reference(s)
T51IKV DNA topoisomerase 2-alphaTOP2A P11388
1 Reference(s)
T25H22 Protein kinase C beta typePRKCB P05771
2 Reference(s)
T46AQJ Glutathione S-transferase PGSTP1 P09211
3 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
7 Reference(s)
T85AXP Cytochrome P450 3A4CYP3A4 P08684
4 Reference(s)
T50SJ8 5'-AMP-activated protein kinase catalytic subunit alpha-2PRKAA2 P54646
1 Reference(s)
T09DI4 Lysine-specific histone demethylase 1AKDM1A O60341
1 Reference(s)
T50SX0 Nuclear receptor subfamily 1 group I member 2NR1I2 O75469
3 Reference(s)
T03YAI Mitogen-activated protein kinase kinase kinase 5MAP3K5 Q99683
1 Reference(s)
T39FBA Thioredoxin-interacting proteinTXNIP Q9H3M7
1 Reference(s)
T64BPL Solute carrier family 23 member 1SLC23A1 Q9UHI7
1 Reference(s)
T60KJ1 Putative endoplasmin-like proteinHSP90B2P Q58FF3
2 Reference(s)
T47H3O Heat shock protein HSP 90-alphaHSP90AA1 P07900
2 Reference(s)
T13KGH TyrosinaseTYR P14679
3 Reference(s)
T73LXA Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1BHSPA1A;HSPA1B P0DMV8;P0DMV9
2 Reference(s)
T46K2X Heat shock 70 kDa protein 4HSPA4 P34932
10 Reference(s)
T31RKU Glycerol kinaseGK P32189
1 Reference(s)
T85JI5 Vitamin D3 receptorVDR P11473
3 Reference(s)
T81I4T 5'-AMP-activated protein kinase catalytic subunit alpha-1PRKAA1 Q13131
3 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
5 Reference(s)
T54G8J Protein kinase C delta typePRKCD Q05655
2 Reference(s)
T65S3S Tyrosine-protein kinase JAK2JAK2 O60674
2 Reference(s)
T68OIU CREB-regulated transcription coactivator 1CRTC1 Q6UUV9
1 Reference(s)
T88BCB Glycerol-3-phosphate phosphatasePGP A6NDG6
1 Reference(s)
T01E7W Aurora kinase BAURKB Q96GD4
1 Reference(s)
T42PUG Solute carrier family 2, facilitated glucose transporter member 1SLC2A1 P11166
2 Reference(s)
T67MQU AntileukoproteinaseSLPI P03973
1 Reference(s)
T19CUN ProthrombinF2 P00734
2 Reference(s)
T01IGB Serine/threonine-protein kinase/endoribonuclease IRE2ERN2 Q76MJ5
1 Reference(s)
T94H37 Cadherin-1CDH1 P12830
1 Reference(s)
T12PIB Lysosomal alpha-glucosidaseGAA P10253
1 Reference(s)
T31U13 Cytochrome P450 2C19CYP2C19 P33261
1 Reference(s)
T70LAB UDP-glucuronosyltransferase 1A9UGT1A9 O60656
1 Reference(s)
T93SFQ NAD-dependent protein deacetylase sirtuin-1SIRT1 Q96EB6
2 Reference(s)
T01CL0 Tyrosine-protein kinase LynLYN P07948
1 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
1 Reference(s)
T90QV5 Voltage-gated hydrogen channel 1HVCN1 Q96D96
1 Reference(s)
T51K6D Tyrosine-protein phosphatase non-receptor type 11PTPN11 Q06124
1 Reference(s)
T70HTD Cytochrome P450 2E1CYP2E1 P05181
1 Reference(s)
T49PL1 Low-density lipoprotein receptorLDLR P01130
1 Reference(s)
T03CZ8 Catechol O-methyltransferaseCOMT P21964
2 Reference(s)
T61QXV Nuclear respiratory factor 1NRF1 Q16656
1 Reference(s)
T82JWE Cellular tumor antigen p53TP53 P04637
7 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
2 Reference(s)
T85U8U Caspase-3CASP3 P42574
19 Reference(s)
T01QLH Estrogen receptorESR1 P03372
1 Reference(s)
T80GUN 72 kDa type IV collagenaseMMP2 P08253
3 Reference(s)
T54VET Protein tyrosine phosphatase type IVA 3PTP4A3 O75365
2 Reference(s)
T11ZYR Cytochrome P450 2D6CYP2D6 P10635
1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
11 Reference(s)
T50WOV ATP-dependent translocase ABCB1ABCB1 P08183
1 Reference(s)
T37BP1 Serine/threonine-protein kinase pim-1PIM1 P11309
1 Reference(s)
T20VPX Cyclin-dependent-like kinase 5CDK5 Q00535
1 Reference(s)
T00RT4 Inosine-5'-monophosphate dehydrogenase 1IMPDH1 P20839
1 Reference(s)
T68B5V Inosine-5'-monophosphate dehydrogenase 2IMPDH2 P12268
1 Reference(s)
T78C6N Cathepsin KCTSK P43235
1 Reference(s)
T75EH8 Glucagon-like peptide 1 receptorGLP1R P43220
1 Reference(s)
T69RXK Cytochrome P450 2C9CYP2C9 P11712
1 Reference(s)
T61OY3 UDP-glucuronosyltransferase 1A1UGT1A1 P22309
1 Reference(s)
T62USB Tumor necrosis factor receptor superfamily member 10ATNFRSF10A O00220
1 Reference(s)
T80D9C Retinoic acid receptor gammaRARG P13631
1 Reference(s)
T83DDX Endothelial protein C receptorPROCR Q9UNN8
1 Reference(s)
T06VX0 MAP/microtubule affinity-regulating kinase 4MARK4 Q96L34
1 Reference(s)
T24C0P Bile acid receptorNR1H4 Q96RI1
1 Reference(s)
T20RA0 Adenosine deaminaseADA P00813
1 Reference(s)
T87DEX Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenaseXDH P47989
4 Reference(s)
T10ICM Oxidized low-density lipoprotein receptor 1OLR1 P78380
1 Reference(s)
T00H7Q Neutrophil cytosol factor 1NCF1 P14598
2 Reference(s)
T39RV3 Dual specificity mitogen-activated protein kinase kinase 1MAP2K1 Q02750
1 Reference(s)
T92Q77 Type I iodothyronine deiodinaseDIO1 P49895
1 Reference(s)
T67HAF Signal transducer and activator of transcription 1-alpha/betaSTAT1 P42224
3 Reference(s)
T07TMB Cyclin-dependent kinase 1CDK1 P06493
3 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
3 Reference(s)
T48XM4 Glutathione S-transferase Mu 2GSTM2 P28161
2 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
11 Reference(s)
T87WYU Glutathione S-transferase Mu 1GSTM1 P09488
2 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
10 Reference(s)
T10HL8 Intercellular adhesion molecule 1ICAM1 P05362
7 Reference(s)
T29MD1 Mitogen-activated protein kinase 8MAPK8 P45983
5 Reference(s)
T41INV Nuclear receptor subfamily 1 group I member 3NR1I3 Q14994
2 Reference(s)
T59IKQ Vascular cell adhesion protein 1VCAM1 P19320
4 Reference(s)
T24U57 E-selectinSELE P16581
2 Reference(s)
T54OSZ PleckstrinPLEK P08567
2 Reference(s)
T63FNY NSFL1 cofactor p47NSFL1C Q9UNZ2
2 Reference(s)
T38T1U Caspase-8CASP8 Q14790
3 Reference(s)
T04TWI CD40 ligandCD40LG P29965
1 Reference(s)
T94S85 Collagen alpha-1(I) chainCOL1A1 P02452
1 Reference(s)
T23P74 Caspase-9CASP9 P55211
1 Reference(s)
T34DZ7 Interleukin-2IL2 P60568
1 Reference(s)
T71GRQ Hexokinase-2HK2 P52789
1 Reference(s)
T99XQ3 DNA topoisomerase 1TOP1 P11387
2 Reference(s)
T66BXF Transcription factor E2F2E2F2 Q14209
1 Reference(s)
T44LWL Transcription factor p65RELA Q04206
10 Reference(s)
T65JYL C-X-C motif chemokine 2CXCL2 P19875
2 Reference(s)
T00CXT Prostaglandin G/H synthase 1PTGS1 P23219
3 Reference(s)
T97FEF Broad substrate specificity ATP-binding cassette transporter ABCG2ABCG2 Q9UNQ0
2 Reference(s)
T24LXT G2/mitotic-specific cyclin-B1CCNB1 P14635
4 Reference(s)
T64W2K Cyclin-dependent kinase inhibitor 1CDKN1A P38936
8 Reference(s)
T41TXS Retinoblastoma-associated proteinRB1 P06400
2 Reference(s)
T28EY5 Serine/threonine-protein kinase Chk2CHEK2 O96017
1 Reference(s)
T54SZZ Endoplasmic reticulum chaperone BiPHSPA5 P11021
1 Reference(s)
T33OPP Interleukin-6IL6 P05231
5 Reference(s)
T64BTV Interleukin-1 betaIL1B P01584
3 Reference(s)
T54CIF Interleukin-8CXCL8 P10145
3 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
11 Reference(s)
T37VLU Interferon gammaIFNG P01579
1 Reference(s)
T16A2X CatalaseCAT P04040
3 Reference(s)
T88B8X Insulin receptorINSR P06213
1 Reference(s)
T68SE0 Solute carrier family 2, facilitated glucose transporter member 4SLC2A4 P14672
2 Reference(s)
T74I49 Bcl-2-like protein 1BCL2L1 Q07817
4 Reference(s)
T00EP2 Tissue-type plasminogen activatorPLAT P00750
4 Reference(s)
T49ORJ Peroxisome proliferator-activated receptor alphaPPARA Q07869
1 Reference(s)
T17UP9 C-C motif chemokine 2CCL2 P13500
3 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
2 Reference(s)
T93WZG G1/S-specific cyclin-D1CCND1 P24385
3 Reference(s)
T42EAZ Vascular endothelial growth factor AVEGFA P15692
3 Reference(s)
T06MQM Heat shock protein beta-1HSPB1 P04792
2 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
1 Reference(s)
T90XYZ C-reactive proteinCRP P02741
2 Reference(s)
T05RAA Inhibitor of nuclear factor kappa-B kinase subunit alphaCHUK O15111
1 Reference(s)
T69NG6 Interleukin-10IL10 P22301
2 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
1 Reference(s)
T26EZU Myc proto-oncogene proteinMYC P01106
2 Reference(s)
T54VQA Cyclin-dependent kinase inhibitor 2ACDKN2A P42771
2 Reference(s)
T55EFK Transcription factor E2F1E2F1 Q01094
1 Reference(s)
T23WMS Cathepsin DCTSD P07339
1 Reference(s)
T84P70 Urokinase-type plasminogen activatorPLAU P00749
3 Reference(s)
T20JZ2 Androgen receptorAR P10275
2 Reference(s)
T91EAB Insulin-like growth factor-binding protein 3IGFBP3 P17936
2 Reference(s)
T94YOD Interferon regulatory factor 1IRF1 P10914
1 Reference(s)
T09AAD NADPH--cytochrome P450 reductasePOR P16435
1 Reference(s)
T67ZT3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENPTEN P60484
1 Reference(s)
T78ZF2 Protein kinase C alpha typePRKCA P17252
1 Reference(s)
T14JZK Receptor tyrosine-protein kinase erbB-3ERBB3 P21860
2 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
2 Reference(s)
T38WWN Serum paraoxonase/arylesterase 1PON1 P27169
1 Reference(s)
T78VUO RAF proto-oncogene serine/threonine-protein kinaseRAF1 P04049
1 Reference(s)
T57GP2 ETS domain-containing protein Elk-1ELK1 P19419
1 Reference(s)
T52CKD Pro-epidermal growth factorEGF P01133
1 Reference(s)
T16OQ5 Puromycin-sensitive aminopeptidaseNPEPPS P55786
1 Reference(s)
T08DOL Sulfotransferase 1E1SULT1E1 P49888
1 Reference(s)
T75HMM Induced myeloid leukemia cell differentiation protein Mcl-1MCL1 Q07820
1 Reference(s)
T37I29 NAVIM2P NA
1 Reference(s)
T77UWH CCAAT/enhancer-binding protein betaCEBPB P17676
1 Reference(s)
T16MRU NACHT, LRR and PYD domains-containing protein 3NLRP3 Q96P20
1 Reference(s)
T54RF5 DnaJ homolog subfamily C member 5DNAJC5 Q9H3Z4
1 Reference(s)
T63DP6 Heterogeneous nuclear ribonucleoprotein A1HNRNPA1 P09651
1 Reference(s)
T25NSJ Mitogen-activated protein kinase 3MAPK3 P27361
2 Reference(s)
T54N7G Fos-related antigen 1FOSL1 P15407
1 Reference(s)
T91OUC Mucin-5ACMUC5AC P98088
1 Reference(s)
T71BDH Mitogen-activated protein kinase 14MAPK14 Q16539
4 Reference(s)
T81MSV Ubiquitin carboxyl-terminal hydrolase 10USP10 Q14694
1 Reference(s)
T03VS9 Protein-tyrosine kinase 2-betaPTK2B Q14289
1 Reference(s)
T88LSZ AromataseCYP19A1 P11511
2 Reference(s)
T48TW0 Platelet glycoprotein 4CD36 P16671
1 Reference(s)
T31SX8 Bone morphogenetic protein 2BMP2 P12643
2 Reference(s)
T36NQ9 Mothers against decapentaplegic homolog 1SMAD1 Q15797
2 Reference(s)
T96OOK Signal transducer and activator of transcription 3STAT3 P40763
2 Reference(s)
T22J9V Tyrosine-protein kinase JAK1JAK1 P23458
1 Reference(s)
T68CKY Tyrosine-protein kinase FynFYN P06241
1 Reference(s)
T37WY2 Phosphoenolpyruvate carboxykinase, cytosolic [GTP]PCK1 P35558
1 Reference(s)
T68AKE Zinc fingers and homeoboxes protein 2ZHX2 Q9Y6X8
1 Reference(s)
T14DX3 Ribosomal protein S6 kinase alpha-3RPS6KA3 P51812
2 Reference(s)
T02GD4 Tumor necrosis factor ligand superfamily member 6FASLG P48023
1 Reference(s)
T89L4V InsulinINS P01308
1 Reference(s)
T21Q0D 3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMGCR P04035
1 Reference(s)
T74V1Z Dual specificity mitogen-activated protein kinase kinase 7MAP2K7 O14733
1 Reference(s)
T07VO1 Steroid hormone receptor ERR1ESRRA P11474
2 Reference(s)
T99ARN Forkhead box protein P3FOXP3 Q9BZS1
1 Reference(s)
T18DUA Tight junction protein ZO-1TJP1 Q07157
3 Reference(s)
T09BRP NAPKB_RS07820 NA
1 Reference(s)
T10IWJ Bone morphogenetic protein receptor type-2BMPR2 Q13873
1 Reference(s)
T75PC7 NAMIR21 NA
1 Reference(s)
T66WWM Claudin-2CLDN2 P57739
1 Reference(s)
T53AOE Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptideTGFB1 P01137
3 Reference(s)
T23LHE Claudin-4CLDN4 O14493
1 Reference(s)
T63YAO Caveolin-1CAV1 Q03135
1 Reference(s)
T31G6V Ras association domain-containing protein 1RASSF1 Q9NS23
1 Reference(s)
T34HYH Interleukin-1 alphaIL1A P01583
1 Reference(s)
T79UQC C-X-C motif chemokine 10CXCL10 P02778
1 Reference(s)
T36SOV Plasminogen activator inhibitor 1SERPINE1 P05121
1 Reference(s)
T50VJF OsteopontinSPP1 P10451
1 Reference(s)
T91MKC Runt-related transcription factor 2RUNX2 Q13950
1 Reference(s)
T17CZC Tissue factorF3 P13726
1 Reference(s)
T84TJB Homeobox protein Nkx-3.1NKX3-1 Q99801
1 Reference(s)
T02WMA Ornithine decarboxylaseODC1 P11926
1 Reference(s)
T38EQ6 NAD(P)H dehydrogenase [quinone] 1NQO1 P15559
1 Reference(s)
T63GUB Proto-oncogene c-FosFOS P01100
1 Reference(s)
T17CNB ThioredoxinTXN P10599
2 Reference(s)
T09KPZ VimentinVIM P08670
1 Reference(s)
T43LYL X-box-binding protein 1XBP1 P17861
1 Reference(s)
T00T9M Thrombospondin-1THBS1 P07996
1 Reference(s)
T61DYZ Phospholipid-transporting ATPase ABCA1ABCA1 O95477
2 Reference(s)
T05WWN CorticoliberinCRH P06850
1 Reference(s)
T47WT6 Breast cancer type 1 susceptibility proteinBRCA1 P38398
1 Reference(s)
T02M5I Monocarboxylate transporter 1SLC16A1 P53985
1 Reference(s)
T30L86 Tumor necrosis factor receptor superfamily member 10BTNFRSF10B O14763
1 Reference(s)
T34Y7V Carbohydrate-responsive element-binding proteinMLXIPL Q9NP71
1 Reference(s)
T12T4H Brain-derived neurotrophic factorBDNF P23560
1 Reference(s)
T57L0X Oxysterols receptor LXR-alphaNR1H3 Q13133
1 Reference(s)
T76CGR Pentraxin-related protein PTX3PTX3 P26022
1 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
1 Reference(s)
T95IYZ AdiponectinADIPOQ Q15848
1 Reference(s)
T91KTQ Methyl-CpG-binding protein 2MECP2 P51608
1 Reference(s)
T04HXV Cytochrome b-c1 complex subunit 1, mitochondrialUQCRC1 P31930
1 Reference(s)
T86O9J NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialNDUFV2 P19404
1 Reference(s)
T67JME Gamma-aminobutyric acid receptor subunit rho-3GABRR3 A8MPY1
1 Reference(s)
T67X1L Eukaryotic translation initiation factor 2 subunit 1EIF2S1 P05198
1 Reference(s)
T29JA7 P2X purinoceptor 4P2RX4 Q99571
1 Reference(s)
T97ESI Apolipoprotein EAPOE P02649
1 Reference(s)
T93NTV KetohexokinaseKHK P50053
1 Reference(s)
T82S6C Hexokinase-4GCK P35557
1 Reference(s)
T74JJN Fatty acid synthaseFASN P49327
2 Reference(s)
T78ILO Stearoyl-CoA desaturaseSCD O00767
1 Reference(s)
T75B9S Cyclic AMP-responsive element-binding protein 1CREB1 P16220
1 Reference(s)
T37ADS Early growth response protein 1EGR1 P18146
1 Reference(s)
T84CEG Claudin-5CLDN5 O00501
1 Reference(s)
T60XS5 Lymphoid enhancer-binding factor 1LEF1 Q9UJU2
1 Reference(s)
T52T5O Axin-1AXIN1 O15169
1 Reference(s)
T78EXU Axin-2AXIN2 Q9Y2T1
1 Reference(s)
T29B10 Interleukin-17AIL17A Q16552
1 Reference(s)
T23KDW Cyclic AMP-dependent transcription factor ATF-4ATF4 P18848
1 Reference(s)
T31JWV Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformPIK3CB P42338
1 Reference(s)
T83QHM Beta-nerve growth factorNGF P01138
1 Reference(s)
T02JCT Protein AATFAATF Q9NY61
1 Reference(s)
T08J6P NAMIR146B NA
1 Reference(s)
T51WGR Pancreas/duodenum homeobox protein 1PDX1 P52945
1 Reference(s)
T90ORW Bcl2-associated agonist of cell deathBAD Q92934
1 Reference(s)
T87QUW Actin, aortic smooth muscleACTA2 P62736
1 Reference(s)
T04WT7 FibronectinFN1 P02751
1 Reference(s)
T04H8Y Beta-secretase 1BACE1 P56817
1 Reference(s)
T57HGP Tumor necrosis factor receptor superfamily member 6FAS P25445
1 Reference(s)

Related Compounds  (Total: 8)

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C0157
Name: Isorhamnetin
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C0164
Name: Kaempferol
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C0156
Name: Isoquercetin
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C0352
Name: Quercetin
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C0229
Name: Myricetin