Target Description

Type Detail
Target ID T80D9C
Protein Name Retinoic acid receptor gamma
Uniprot ID P13631
Protein Name Alias RAR-gamma;  Nuclear receptor subfamily 1 group B member 3
Gene ID 5916
Gene Symbol RARG
Gene Alias NR1B3
TTD T82146: Successful target
Pfam PF00105 ; PF00104
GO
0003677:DNA binding

0005634:nucleus

0035264:multicellular organism growth

0032331:negative regulation of chondrocyte differentiation

0070384:Harderian gland development

0045637:regulation of myeloid cell differentiation

0003682:chromatin binding

0060534:trachea cartilage development

0008284:positive regulation of cell population proliferation

0008285:negative regulation of cell population proliferation

0032526:response to retinoic acid

0031076:embryonic camera-type eye development

0005737:cytoplasm

0002068:glandular epithelial cell development

0009755:hormone-mediated signaling pathway

0001843:neural tube closure

0030154:cell differentiation

0060070:canonical Wnt signaling pathway

0000785:chromatin

0016021:integral component of membrane

0035116:embryonic hindlimb morphogenesis

0009952:anterior/posterior pattern specification

0031641:regulation of myelination

0005667:transcription regulator complex

0048384:retinoic acid receptor signaling pathway

0060324:face development

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0043065:positive regulation of apoptotic process

0071300:cellular response to retinoic acid

0000122:negative regulation of transcription by RNA polymerase II

0008270:zinc ion binding

0003700:DNA-binding transcription factor activity

0003430:growth plate cartilage chondrocyte growth

0006367:transcription initiation from RNA polymerase II promoter

0046965:retinoid X receptor binding

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

1990837:sequence-specific double-stranded DNA binding

0008361:regulation of cell size

0060740:prostate gland epithelium morphogenesis

1990830:cellular response to leukemia inhibitory factor

0045944:positive regulation of transcription by RNA polymerase II

0004879:nuclear receptor activity

0043068:positive regulation of programmed cell death

0048048:embryonic eye morphogenesis

PDB 3LBD ; 5M24 ; 1FCZ ; 2LBD ; 1EXA ; 1EXX ; 1FCX ; 1FD0 ; 1FCY ; 4LBD ; 6FX0
Drugbank DB07031 ; DB03279 ; DB07294 ; DB02741 ; DB00982 ; DB00210 ; DB02258 ; DB00755 ; DB00799 ; DB00459 ; DB05467 ; DB02466 ; DB00523 ; DB05785 ; DB12808 ; DB03466 ; DB00926
KEGG hsa:5916

Related Compounds  (Total: 2)

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C0456
Name: Tretinoin
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C0845
Name: Acacetin


Related Herbs  (Total: 31)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0625 Ce Bai Tan侧柏炭 Oriental arbor-vitaePlatycladus orientalis
H0663 Xiao Ji小蓟 Setose thistleCirsium setosum
H0073 Jing Jie Sui荆芥穗 NASchizonepetae spica
H0095 Gou Qi Zi枸杞子 Chinese wolfberry fruitLycium chinense
H0426 Shan Zhi Ma Gan Jin Gao山芝麻干浸膏 Narrowleaf screwtreeHelicteres angustifolia
H0053 Jin Lian Hua金莲花 Chinese globeflowerTrollius chinensis
H1254 Huang Qin Tan黄芩炭 Extract of root of Baikal skullcaapScutellaria baicalensis
H0092 Ju Hua菊花 Florists chrysanthemum flowerChrysanthemum morifolium
H0729 Ye Ju Hua野菊花 Indian wild chrysanthemum flowerChrysanthemum indicum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0438 Shen Jin Cao伸筋草 Common japanese clubmossLycopodium japonicum
H0094 Gou Qi枸杞 Chinese wolfberry fruitLycium chinense
H1183 Hong Dou红豆 Hosie ormosiaOrmosia hosiei
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H0002 Hui Xiang茴香 Fennel fruitFoeniculum vulgare
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0290 Niu Er Feng牛耳枫 calyx-shaped daphniphyllum fruitDaphniphyllum calycinum
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H1251 Huang Qin黄芩 Root of Baikal skullcaapScutellaria baicalensis
H1253 Huang Qin Jin Gao Fen黄芩浸膏粉 Extract of root of Baikal skullcaapScutellaria baicalensis
H0310 Pian Qin片芩 Scutellaria amoenaScutellaria baicalensis
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H0425 Shan Zhi Ma山芝麻 Narrowleaf screwtreeHelicteres angustifolia
H0247 Mi Meng Hua密蒙花 Pale butterflybushBuddleja officinalis
H1161 Hang Ju杭菊 Chrysanthemum flowerChrysanthemum morifolium
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H1138 Bai Jiang Cao败酱草 All - grass of dahurian patriniaThlaspi arvense
H1252 Huang Qin Jin Gao黄芩浸膏 Extract of root of Baikal skullcaapScutellaria baicalensis