HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T06VX0	MAP/microtubule affinity-regulating kinase 4	MARK4	Q96L34	2 Reference(s)
T90LA2	Sphingomyelin phosphodiesterase	SMPD1	P17405	1 Reference(s)
T37PX5	Zinc finger protein GLI1	GLI1	P08151	1 Reference(s)
T04MBA	Vascular endothelial growth factor receptor 2	KDR	P35968	2 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	2 Reference(s)
T09INZ	Transient receptor potential cation channel subfamily A member 1	TRPA1	O75762	3 Reference(s)
T60XJI	Transient receptor potential cation channel subfamily M member 8	TRPM8	Q7Z2W7	3 Reference(s)
T67KTV	Transient receptor potential cation channel subfamily V member 1	TRPV1	Q8NER1	1 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	2 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	1 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	2 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	4 Reference(s)
T74P7I	G-protein coupled bile acid receptor 1	GPBAR1	Q8TDU6	2 Reference(s)
T02O3F	Endothelial lipase	LIPG	Q9Y5X9	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	2 Reference(s)
T70KPE	Transient receptor potential cation channel subfamily V member 3	TRPV3	Q8NET8	3 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	1 Reference(s)
T05TS9	Cocaine esterase	CES2	O00748	1 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	2 Reference(s)
T25M2J	Anoctamin-1	ANO1	Q5XXA6	1 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	4 Reference(s)
T34DZ7	Interleukin-2	IL2	P60568	2 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	2 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	3 Reference(s)
T38N69	Lymphokine-activated killer T-cell-originated protein kinase	PBK	Q96KB5	1 Reference(s)
T09BRP	NA	PKB_RS07820	NA	1 Reference(s)
T83P5X	Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB	O14920	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	4 Reference(s)
T74LFK	Neurogenic locus notch homolog protein 1	NOTCH1	P46531	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	4 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	7 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	1 Reference(s)
T43N2D	Epidermal growth factor receptor	EGFR	P00533	1 Reference(s)
T20JZ2	Androgen receptor	AR	P10275	1 Reference(s)
T53YWQ	Pro-neuropeptide Y [Cleaved into: Neuropeptide Y	NPY	P01303	2 Reference(s)
T95LIF	Cannabinoid receptor 2	CNR2	P34972	11 Reference(s)
T12WTT	Interleukin-5	IL5	P05113	1 Reference(s)
T84W8G	Aryl hydrocarbon receptor	AHR	P35869	1 Reference(s)
T41A4Y	Lamin-B1	LMNB1	P20700	1 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	3 Reference(s)
T21Q0D	3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMGCR	P04035	1 Reference(s)
T44KU9	Cytochrome P450 2B6	CYP2B6	P20813	1 Reference(s)
T75H3W	Cyclin-dependent kinase 2	CDK2	P24941	1 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	1 Reference(s)
T16Q09	Bcl-2 homologous antagonist/killer	BAK1	Q16611	1 Reference(s)
T06Q1R	Amine oxidase [flavin-containing] B	MAOB	P27338	2 Reference(s)
T69XVX	Cytochrome P450 1B1	CYP1B1	Q16678	1 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	4 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	4 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	1 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	1 Reference(s)
T75PC7	NA	MIR21	NA	1 Reference(s)
T66G0O	NA	MIR30A	NA	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	1 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	1 Reference(s)
T42K6K	M-phase inducer phosphatase 3	CDC25C	P30307	1 Reference(s)
T04A2Q	Serine/threonine-protein kinase PLK1	PLK1	P53350	1 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	1 Reference(s)
T77M4W	Adenosine receptor A2a	ADORA2A	P29274	1 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	1 Reference(s)
T30VNV	Myeloperoxidase	MPO	P05164	2 Reference(s)
T12T4H	Brain-derived neurotrophic factor	BDNF	P23560	1 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	1 Reference(s)
T23EWB	Transcriptional repressor protein YY1	YY1	P25490	1 Reference(s)
T38K2W	Receptor tyrosine-protein kinase erbB-2	ERBB2	P04626	1 Reference(s)
T42D4V	Histone deacetylase 1	HDAC1	Q13547	1 Reference(s)
T39M6J	ATP-binding cassette sub-family C member 2	ABCC2	Q92887	1 Reference(s)
T70SFS	Superoxide dismutase [Mn], mitochondrial	SOD2	P04179	1 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	1 Reference(s)
T21UJU	Troponin I, cardiac muscle	TNNI3	P19429	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T69X4A	14-3-3 protein sigma	SFN	P31947	1 Reference(s)
T37VLU	Interferon gamma	IFNG	P01579	1 Reference(s)
T58H37	Perforin-1	PRF1	P14222	1 Reference(s)
T16CFE	Lysosome-associated membrane glycoprotein 1	LAMP1	P11279	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	1 Reference(s)
T49PL1	Low-density lipoprotein receptor	LDLR	P01130	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	1 Reference(s)

Herb ID: H0968	Chinese Character: 地枫皮
English Name: Difengpi anisetree	Latin Name: Illicium difengpi
Chinese Pin Yin : Di Feng Pi	TCM-ID: TCMH447
Therapeutic Function in Chinese : NA	Therapeutic Function in English: NA
Herb Function: Relieve rheumatic conditions, and promote the flow of qi and relieve pain

Herb Description

Related Targets (Total: 85)

Related Compounds (Total: 20)