HIT-result

Type	Detail
Target ID	T90LA2
Protein Name	Sphingomyelin phosphodiesterase
Uniprot ID	P17405
Protein Name Alias	EC 3.1.4.12; Acid sphingomyelinase; aSMase
Gene ID	6609
Gene Symbol	SMPD1
Gene Alias	ASM
TTD	NA
Pfam	PF00149
GO	0061750:acid sphingomyelin phosphodiesterase activity 0006687:glycosphingolipid metabolic process 0035307:positive regulation of protein dephosphorylation 0045807:positive regulation of endocytosis 0070062:extracellular exosome 0034340:response to type I interferon 0007399:nervous system development 0010212:response to ionizing radiation 0034644:cellular response to UV 0001778:plasma membrane repair 0070555:response to interleukin-1 0005615:extracellular space 0034612:response to tumor necrosis factor 0006685:sphingomyelin catabolic process 0005886:plasma membrane 0005764:lysosome 0042599:lamellar body 0042493:response to drug 0046718:viral entry into host cell 0006684:sphingomyelin metabolic process 0043202:lysosomal lumen 0071277:cellular response to calcium ion 0009615:response to virus 0023021:termination of signal transduction 0043065:positive regulation of apoptotic process 0036019:endolysosome 0004767:sphingomyelin phosphodiesterase activity 0008270:zinc ion binding 0007165:signal transduction 0008081:phosphoric diester hydrolase activity 0005811:lipid droplet 0043407:negative regulation of MAP kinase activity 0042060:wound healing 0016798:hydrolase activity, acting on glycosyl bonds 0046513:ceramide biosynthetic process 0008203:cholesterol metabolic process 0005768:endosome 0042220:response to cocaine
PDB	5JG8 ; 5I8R ; 5I81 ; 5I85
Drugbank	DB14009 ; DB00381 ; DB00477 ; DB01151
KEGG	hsa:6609

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Name: Morphine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0757	Ying Su Ke	罂粟壳	Opium poppy pericarp	Papaver somniferum
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H0248	Mi Ying Su Ke	蜜罂粟壳	Opium poppy	Papaver somniferum
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0532	Teng Huang	藤黄	Gamboge tree resin	Garcinia morella
H0756	Ying Su	罂粟	Opium poppy	Papaver somniferum
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0968	Di Feng Pi	地枫皮	Difengpi anisetree	Illicium difengpi