Target Description
| Type | Detail |
|---|---|
| Target ID | T05TS9 |
| Protein Name | Cocaine esterase |
| Uniprot ID |
O00748 |
| Protein Name Alias | EC 3.1.1.84; Carboxylesterase 2; CE-2; hCE-2; EC 3.1.1.1; Methylumbelliferyl-acetate deacetylase 2; EC 3.1.1.56 |
| Gene ID |
8824 |
| Gene Symbol | CES2 |
| Gene Alias | ICE |
| TTD | NA |
| Pfam | PF00135 |
| GO |
0047374:methylumbelliferyl-acetate deacetylase activity
0004806:triglyceride lipase activity 0005783:endoplasmic reticulum 0006805:xenobiotic metabolic process 0080030:methyl indole-3-acetate esterase activity 0005615:extracellular space 0004771:sterol esterase activity 0052689:carboxylic ester hydrolase activity 0005788:endoplasmic reticulum lumen 0006693:prostaglandin metabolic process 0009056:catabolic process 0016042:lipid catabolic process |
| PDB | NA |
| Drugbank | DB06695 ; DB06209 ; DB00762 ; DB14845 |
| KEGG | hsa:8824 |
Related Compounds (Total: 6)
C0102
Name: Geraniol
C0196
Name: Loperamide
C0401
Name: Shikonin
C0529
Name: Kushenol X
C1046
Name: vinblastine
Related Herbs (Total: 62)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0575 | Tu Ku Shen | 土苦参 | all-grass of hooker winghead | Sophora flavescens |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0651 | Xiang Yuan | 香橼 | Wilson citron | Citrus medica |
| H0242 | Bei Sha Shen Liu Jin Gao | 北沙参流浸膏 | Glehnia littoralis | Glehnia littoralis |
| H0303 | Bi Cheng Qie | 毕澄茄 | Cubeba pepper | Piper cubeba |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0237 | Mei Gui Hua | 玫瑰花 | Rugose rose flower | Rosa rugosa |
| H0273 | Mu Tong | 木通 | Fiveleaf akebia | Akebia quinata |
| H1005 | Dou Chi Jiang | 豆豉姜 | Folium litseae cubebae | Litsea cubeba |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H0390 | Sang Ji Sheng | 桑寄生 | Parasite scurrula | Loranthus parasiticus |
| H0609 | Wu Wei Zi Liu Jin Gao | 五味子流浸膏 | Five-flavor berry | Schisandra chinensis |
| H0154 | Ai Ye You | 艾叶油 | Argy wormwood leaf | Artemisia argyi |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0746 | Yin Chen Hao Gan Jin Gao | 茵陈蒿干浸膏 | Capillary wormwood | Artemisia capillaris |
| H0745 | Yin Chen Hao | 茵陈蒿 | Capillary wormwood | Artemisia capillaris |
| H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1183 | Hong Dou | 红豆 | Hosie ormosia | Ormosia hosiei |
| H0028 | Jiang Huang | 姜黄 | Common turmeric | Curcuma longa |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0606 | Wu Wei Zi Chun Jin Gao | 五味子醇浸膏 | Five-flavor berry | Schisandra chinensis |
| H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
| H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
| H0533 | Teng Ku Shen | 藤苦参 | NA | Sophora flavescens |
| H1214 | Hua Jiao | 花椒 | Bunge pricklyash | Zanthoxylum bungeanum |
| H0968 | Di Feng Pi | 地枫皮 | Difengpi anisetree | Illicium difengpi |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H0063 | Jin Ye Zi | 金叶子 | Yunnan craibiodendron | Craibiodendron yunnanese |
| H0652 | Xiang Yuan Pi | 香橼皮 | Wilson citron | Citrus medica |
| H0103 | Ai Ye | 艾叶 | Argy wormwood leaf | Artemisia argyi |
| H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
| H0111 | Ku Shen | 苦参 | Lightyellow sophora | Sophora flavescens |
| H0585 | Tu Yin Chen Hao | 土茵陈蒿 | Capillary wormwood | Artemisia capillaris |
| H0607 | Wu Wei Zi Jin Chu Wu | 五味子浸出物 | Five-flavor berry | Schisandra chinensis |
| H0844 | Zi Cao | 紫草 | Redroot gromwell | Lithospermum erythrorhizon |
| H0410 | Shan Jiang Zi | 山姜子 | NA | Litsea cubeba |
| H0986 | Dian Zi Cao | 滇紫草 | Paniculate onosma | Onosma paniculatum |
| H0239 | Bei Sha Shen | 北沙参 | Coastal glehnia | Glehnia littoralis |
| H1011 | Bai Chou | 白丑 | Pharbitis seed | Semen pharbitidis |
| H0673 | Xin Jiang Zi Cao | 新疆紫草 | Arnebia root | Arnebia euchroma |
| H0088 | Ju He | 橘核 | Tangerine seed | Citrus reticulata |
| H0238 | Mei Hua | 梅花 | Plum flower | Flos mume |
| H0164 | Ban Zhi Lian | 半枝莲 | Barbed skullcap | Scutellaria barbata |
| H0403 | Shan Cang Zi | 山苍子 | NA | Litsea cubeba |
| H0093 | Ju Pi | 橘皮 | Tangerine pericarp | Citrus reticulata |
| H0613 | Wu Yue Ai | 五月艾 | Artemisia | Artemisia princeps |
| H1109 | Bai Hua She She Cao | 白花蛇舌草 | Spreading hedyitis | Oldenlandia diffusa |
| H0418 | Shan Yin Chen | 山茵陈 | Capillary wormwood | Artemisia capillaris |
| H0895 | Chuan Yu Jin | 川郁金 | Turmeric | Curcuma longa |
| H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
| H0608 | Wu Wei Zi Jin Gao | 五味子浸膏 | Five-flavor berry | Schisandra chinensis |
| H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
| H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
| H1173 | Hei Chou | 黑丑 | Pharbitis seed | Semen pharbitidis |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0605 | Wu Wei Zi | 五味子 | Chinese magnoliavine | Schisandra chinensis |
| H0089 | Ju Hong | 橘红 | NA | Citri exocarpium rubrum |
| H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |