HIT-result

Type	Detail
Target ID	T69X4A
Protein Name	14-3-3 protein sigma
Uniprot ID	P31947
Protein Name Alias	Epithelial cell marker protein 1; Stratifin
Gene ID	2810
Gene Symbol	SFN
Gene Alias	HME1
TTD	NA
Pfam	PF00244
GO	1900740:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0005634:nucleus 0005829:cytosol 0008630:intrinsic apoptotic signaling pathway in response to DNA damage 0061436:establishment of skin barrier 0045296:cadherin binding 0010839:negative regulation of keratinocyte proliferation 0000079:regulation of cyclin-dependent protein serine/threonine kinase activity 0045606:positive regulation of epidermal cell differentiation 0042802:identical protein binding 0005615:extracellular space 0003334:keratinocyte development 0008426:protein kinase C inhibitor activity 0031424:keratinization 0007165:signal transduction 0070062:extracellular exosome 0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0051219:phosphoprotein binding 0001836:release of cytochrome c from mitochondria 0006469:negative regulation of protein kinase activity 0046827:positive regulation of protein export from nucleus 0010482:regulation of epidermal cell division 0019901:protein kinase binding 0030307:positive regulation of cell growth 0006977:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0005739:mitochondrion
PDB	6RKK ; 6TM7 ; 6G8Q ; 4DHT ; 4DHP ; 6T5H ; 6G8L ; 6RWI ; 6T5F ; 4DHO ; 6YP3 ; 6G6X ; 3SPR ; 6YOX ; 3SMM ; 5HF3 ; 5LU1 ; 6Y8E ; 3T0L ; 6YLU ; 6FAU ; 4FL5 ; 6Y1D ; 6HMT ; 3LW1 ; 4QLI ; 6QDU ; 6RWS ; 6S9Q ; 6Y3R ; 6RM7 ; 6QDR ; 4JDD ; 6HKB ; 6Y3M ; 1YZ5 ; 5MYC ; 3MHR ; 6RJL ; 6RJQ ; 6Y8A ; 5LTW ; 6W0L ; 6RJZ ; 6RK8 ; 6TWZ ; 5OEH ; 6YP2 ; 6NV2 ; 6FCP ; 6FAV ; 6Y3O ; 4DAT ; 6XY5 ; 6YP8 ; 6SLX ; 3P1S ; 6Y8D ; 3IQJ ; 4Y32 ; 6QHM ; 6R5L ; 7AEW ; 3P1O ; 4DHR ; 6FBY ; 6SIQ ; 6RWU ; 6HHP ; 6RL3 ; 6SIO ; 5OMA ; 6RL4 ; 6RP6 ; 3IQU ; 5MY9 ; 6QDT ; 6QIU ; 3SMK ; 5N5W ; 6Y40 ; 6YOW ; 6SLV ; 6Y3V ; 6S3C ; 3SMN ; 5MXO ; 4IEA ; 6RX2 ; 3UX0 ; 6RWH ; 3SML ; 6G8P ; 6TLG ; 6Y3W ; 6XXC ; 5N5T ; 6YPY ; 6Y18 ; 6YPL ; 6T80 ; 6QHL ; 5N5R ; 6FBB ; 6FI5 ; 6RHC ; 3P1N ; 5MOC ; 5OKF ; 5OK9 ; 6TL3 ; 6YOY ; 4Y5I ; 6QZS ; 4DHQ ; 5OM0 ; 4DHU ; 4DHS ; 6Y44 ; 1YWT ; 6RKM ; 6SIN ; 5N75 ; 6YQ2 ; 6FBW ; 6G8K ; 4DHN ; 4Y3B ; 3O8I ; 6RKI ; 6TLF ; 6S40 ; 6Y3S ; 5OEG ; 6TCH ; 4FR3 ; 4DAU ; 3SMO ; 6ZCJ ; 6RL6 ; 6QZR ; 6G8J ; 5LU2 ; 6Y8B ; 4JC3 ; 6Y58 ; 6XWD ; 3T0M ; 6QDS ; 6SLW ; 3SP5 ; 6FI4 ; 6G8I ; 4DHM ; 6Y1J ; 6TJM ; 6SIP ; 6FAW ; 3P1P ; 6S39 ; 3IQV ; 5MHC ; 6HMU ; 5BTV ; 6RM5 ; 3P1R ; 3U9X ; 6HKF ; 3P1Q ; 6GHP ; 6HN2
Drugbank	NA
KEGG	hsa:2810

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0289	Niu Bang Zi	牛蒡子	Great burdock fruit	Arctium lappa
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0463	Shi Liu Pi	石榴皮	Pomegranate peel	Punica granatum
H0045	Jin Fei Cao	金沸草	Japanese inula	Inula japonica
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0314	Pu Gong Ying	蒲公英	Mongolian dandelion	Taraxacum mongolicum
H0974	Di Jin Cao	地锦草	Humifuse euphorbia	Euphorbia humifusa
H0111	Ku Shen	苦参	Lightyellow sophora	Sophora flavescens
H1203	Hu Ji Sheng	槲寄生	Colored mistletoe	Viscum coloratum
H0060	Jin Si Ku Lian	金丝苦楝	NA	Cardiospermum halicacabum
H0315	Pu Gong Ying Jin Gao	蒲公英浸膏	Mongolian dandelion	Taraxacum mongolicum
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H0918	Cu Yuan Hua	醋芫花	Lilac daphne	Daphne genkwa
H0279	Nan Gua	南瓜	Cushaw	Cucurbita moschata
H0327	Qian Li Guang	千里光	Climbing groundsel	Senecio scandens
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H1124	Guang Jin Qian Cao	广金钱草	Snowbellleaf tickclover	Desmodium styracifolium
H0663	Xiao Ji	小蓟	Setose thistle	Cirsium setosum
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0762	Yu Li Ren	郁李仁	NA	Prunus japonica
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0370	Ru Xiang	乳香	Olibanum	Boswellia carterii
H0216	Man Jing Ye	蔓荆叶	Threeleaf chastetree leaf	Vitex trifolia
H0318	Pu Tao(1)	蒲桃	Syzygium	Syzygium jambos
H0152	Ling Zhi Jin Gao	灵芝浸膏	NA	Ganoderma lucidum
H0975	Di Mian Cao	地绵草	NA	Euphorbia humifusa
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H1179	Hei Mian Shen	黑面神	Leaf and twig of fruticose breynia	Breynia fruticosa
H0297	Niu Xi	牛膝	Twotooth achyranthes	Achyranthes bidentata
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0855	Chuan Bei Mu	川贝母	Fritillaria unibracteata	Fritillaria cirrhosa
H0707	Yuan Hua	芫花	Lilac daphne	Daphne genkwa
H1244	Huang Miao	黄苗	NA	Taraxacum mongolicum
H0575	Tu Ku Shen	土苦参	all-grass of hooker winghead	Sophora flavescens
H0710	Yuan Hua Tiao	芫花条	stem of lilac daphne	Daphne genkwa
H0689	Xue Feng Teng	血风藤	NA	Ventilago leiocarpa
H0968	Di Feng Pi	地枫皮	Difengpi anisetree	Illicium difengpi
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0738	Yi Xing Nan Wu Wei Zi	异型南五味子	Curious kadsura	Kadsura heteroclita
H0885	Chuan Xi Zhang Ya Cai	川西獐牙菜	Mussot swertia	Swertia mussotii
H0859	Chuan Bei Mu Liu Jin Gao	川贝母流浸膏	Fritillaria unibracteata	Fritillaria cirrhosa
H0214	Bei He Huan	北合欢	Albizia	Albizia julibrissin
H0300	Nv Zhen Zi	女贞子	Glossy privet fruit	Ligustrum lucidum
H0153	Ling Zhi(1)	灵芝	Lucid ganoderma	Ganoderma lucidum
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0533	Teng Ku Shen	藤苦参	NA	Sophora flavescens
H1184	Bai Lian	白蔹	Japanese ampelopsis	Ampelopsis japonica
H1133	Gui Jian Yu	鬼箭羽	Winged euonymus	Euonymus alatus
H0708	Yuan Hua Gen	芫花根	Lilac daphne root	Daphne genkwa
H1034	Fei Yang Cao	飞杨草	NA	Euphorbia hirta
H0120	Ban Bian Qi	半边旗	pinnated brake herb	Pteris semipinnata
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0462	Shi Liu	石榴	Pomegranate fruit	Punica granatum
H0515	Suan Shi Liu	酸石榴	Pomegranate	Punica granatum
H0464	Shi Liu Zi	石榴子	NA	Punica granatum
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0296	Niu Teng	牛藤	twotooth achyranthes root	Achyranthes bidentata
H0217	Man Jing Zi	蔓荆子	Threeleaf chastetree fruit	Vitex trifolia
H0711	Yuan Hua Zhi Tiao	芫花枝条	stem of lilac daphne	Daphne genkwa

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 60)