Target Description

Type Detail
Target ID T16YT9
Protein Name Parathyroid hormone
Uniprot ID P01270
Protein Name Alias PTH;  Parathormone;  Parathyrin
Gene ID 5741
Gene Symbol PTH
Gene Alias NA
TTD T98708: Successful target
Pfam PF01279
GO
0007189:adenylate cyclase-activating G protein-coupled receptor signaling pathway

0071866:negative regulation of apoptotic process in bone marrow cell

0010960:magnesium ion homeostasis

0046058:cAMP metabolic process

0045725:positive regulation of glycogen biosynthetic process

1900158:negative regulation of bone mineralization involved in bone maturation

0005179:hormone activity

0001501:skeletal system development

0071774:response to fibroblast growth factor

0005615:extracellular space

0010629:negative regulation of gene expression

0033280:response to vitamin D

0045944:positive regulation of transcription by RNA polymerase II

0005576:extracellular region

0048018:receptor ligand activity

0010468:regulation of gene expression

0007202:activation of phospholipase C activity

0006874:cellular calcium ion homeostasis

0008628:hormone-mediated apoptotic signaling pathway

0032331:negative regulation of chondrocyte differentiation

0045471:response to ethanol

0048873:homeostasis of number of cells within a tissue

0002862:negative regulation of inflammatory response to antigenic stimulus

0055062:phosphate ion homeostasis

0071864:positive regulation of cell proliferation in bone marrow

0071107:response to parathyroid hormone

0090290:positive regulation of osteoclast proliferation

0010288:response to lead ion

0009967:positive regulation of signal transduction

0046686:response to cadmium ion

0007266:Rho protein signal transduction

0031856:parathyroid hormone receptor binding

0047485:protein N-terminus binding

0007186:G protein-coupled receptor signaling pathway

0051428:peptide hormone receptor binding

0045453:bone resorption

0034645:cellular macromolecule biosynthetic process

0042493:response to drug

0031857:type 1 parathyroid hormone receptor binding

0007267:cell-cell signaling

0060732:positive regulation of inositol phosphate biosynthetic process

0030501:positive regulation of bone mineralization

0046326:positive regulation of glucose import

PDB 1HPY ; 1ZWE ; 2L1X ; 1HPH ; 1ZWG ; 1FVY ; 1ET2 ; 1HTH ; 1ET1 ; 1BWX ; 1ZWD ; 1ZWF ; 1ZWA ; 1ZWB ; 3C4M
Drugbank DB04419 ; DB05883
KEGG hsa:5741

Related Compounds  (Total: 2)

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C0655
Name: 25-Hydroxycholecalciferol
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C1233
Name: Cholecalciferol


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens