Target Description

Type Detail
Target ID T45B9P
Protein Name ATP-sensitive inward rectifier potassium channel 11
Uniprot ID Q14654
Protein Name Alias IKATP;  Inward rectifier K(+) channel Kir6.2;  Potassium channel, inwardly rectifying subfamily J member 11
Gene ID 3767
Gene Symbol KCNJ11
Gene Alias NA
TTD T00820: Research target
Pfam PF17655 ; PF01007
GO
0033574:response to testosterone

0005768:endosome

0055085:transmembrane transport

0050877:nervous system process

0030506:ankyrin binding

0050796:regulation of insulin secretion

0005829:cytosol

0071316:cellular response to nicotine

0042391:regulation of membrane potential

0008022:protein C-terminus binding

0070852:cell body fiber

0034765:regulation of ion transmembrane transport

0006006:glucose metabolic process

0071805:potassium ion transmembrane transport

0044325:ion channel binding

0005783:endoplasmic reticulum

0014704:intercalated disc

0005524:ATP binding

0015272:ATP-activated inward rectifier potassium channel activity

0008282:inward rectifying potassium channel

0031072:heat shock protein binding

0002931:response to ischemia

0030955:potassium ion binding

0005635:nuclear envelope

0071333:cellular response to glucose stimulus

0071356:cellular response to tumor necrosis factor

0046676:negative regulation of insulin secretion

0005242:inward rectifier potassium channel activity

0030673:axolemma

0001669:acrosomal vesicle

0030315:T-tubule

0043025:neuronal cell body

0005886:plasma membrane

1990573:potassium ion import across plasma membrane

1903779:regulation of cardiac conduction

0033198:response to ATP

0005249:voltage-gated potassium channel activity

0005887:integral component of plasma membrane

0042493:response to drug

0019829:ATPase-coupled cation transmembrane transporter activity

0098662:inorganic cation transmembrane transport

1903078:positive regulation of protein localization to plasma membrane

2001259:positive regulation of cation channel activity

0032355:response to estradiol

0043209:myelin sheath

0005739:mitochondrion

PDB 6C3P ; 6C3O
Drugbank DB01119 ; DB00839 ; DB00222 ; DB01154 ; DB00661 ; DB11148 ; DB00308 ; DB00922 ; DB01016 ; DB11633 ; DB01392
KEGG hsa:3767

Related Compounds  (Total: 3)

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C1115
Name: cocaine
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C1205
Name: Caffeine
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C1227
Name: Chelerythrine


Related Herbs  (Total: 19)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H1212 Hu Ye Gan Jin Gao槲叶干浸膏 NAQuercus dentata
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1181 Hei Zhi Ma黑芝麻 Oriental sesameSesamum indicum
H1004 Bai Cha白茶 White teaCamellia sinensis
H1214 Hua Jiao花椒 Bunge pricklyashZanthoxylum bungeanum
H1033 Fang Ji防己 Fourstamen stephaniaStephania tetrandra
H1163 He Bao Cao荷包草 NALamprocapnos spectabilis
H0233 Mao Liang Mian Zhen毛两面针 NAZanthoxylum nitidum
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1029 Fang Er Cha方儿茶 khair in hindiSenegalia catechu
H0615 Wu Zhi Mao Tao五指毛桃 five-finger fig rootFicus simplicissima
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0603 Wu Tong Ye Jin Gao梧桐叶浸膏 Parasol treesFirmiana simplex
H0637 Cha Ye茶叶 Common teaCamellia sinensis
H1207 Hu Ma胡麻 white seed of oriental sesameSesamum indicum
H1208 Hu Ma Ren胡麻仁 white seed of oriental sesameSesamum indicum
H0341 Qing Feng Teng青风藤 OrientvineSinomenium acutum
H0087 Ju Gu Ye枸骨叶 FOLIUM iLICIS cORNUTAEIlex cornuta