Target Description
| Type | Detail |
|---|---|
| Target ID | T80U0C |
| Protein Name | Glutathione synthetase |
| Uniprot ID |
P48637 |
| Protein Name Alias | GSH synthetase; GSH-S; EC 6.3.2.3; Glutathione synthase |
| Gene ID |
2937 |
| Gene Symbol | GSS |
| Gene Alias | NA |
| TTD | T69420: Research target |
| Pfam | PF03917 ; PF03199 |
| GO |
0070062:extracellular exosome
0007399:nervous system development 0005524:ATP binding 0031667:response to nutrient levels 0043200:response to amino acid 0005829:cytosol 0042802:identical protein binding 0009410:response to xenobiotic stimulus 0046686:response to cadmium ion 0000287:magnesium ion binding 0006750:glutathione biosynthetic process 0043295:glutathione binding 0007568:aging 0034612:response to tumor necrosis factor 0006520:cellular amino acid metabolic process 0042803:protein homodimerization activity 0004363:glutathione synthase activity 0006979:response to oxidative stress 0016594:glycine binding |
| PDB | 2HGS |
| Drugbank | DB09130 ; DB00151 ; DB04395 ; DB06151 ; DB03408 ; DB00143 ; DB00145 |
| KEGG | hsa:2937 |
Related Herbs (Total: 104)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0104 | Bai Zhu | 白术 | Largehead atractylodes | Atractylodes macrocephala |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
| H0342 | Qing Hao | 青蒿 | sweet wormwood | Artemisia carvifolia |
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china |
| H0362 | Rong Shu Xu | 榕树须 | Banyan | Ficus microcarpa |
| H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H1140 | Guo Gang Long | 过岗龙 | NA | Entada phaseoloides |
| H0181 | Luo Bu Ma | 罗布麻 | Dogbane | Apocynum venetum |
| H0601 | Wu Mei | 乌梅 | Japanese apricot | Prunus mume |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
| H0818 | Zhi Zi | 栀子 | Cape jasmine fruit | Gardenia jasminoides |
| H1068 | Bai He Liu Jin Gao | 百合流浸膏 | Lily | Lilium brownii |
| H1034 | Fei Yang Cao | 飞杨草 | NA | Euphorbia hirta |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0765 | Chi Dou | 赤豆 | Assuki bean | Vigna angularis |
| H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
| H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
| H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |
| H0020 | Ji Yan Cao | 鸡眼草 | Striate kummerowia | Kummerowia striata |
| H0229 | Mao Da Ding Cao | 毛大丁草 | Pilose gerbera | Gerbera piloselloides |
| H1099 | Gou Teng | 钩藤 | Sharpleaf gambirplant | Uncaria rhynchophylla |
| H0868 | Chuan Du Huo | 川独活 | Doubleteeth pubescent angelica | Angelica pubescens |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0615 | Wu Zhi Mao Tao | 五指毛桃 | five-finger fig root | Ficus simplicissima |
| H0565 | Tu Bie Chong | 土鳖虫 | Cockroach | Eupolyphaga sinensis |
| H0351 | Quan Shen | 拳参 | Bistort | Polygonum bistorta |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0424 | Shan Zhi | 山栀 | Cape jasmine | Gardenia jasminoides |
| H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
| H0519 | Suo Yang | 锁阳 | Songaria cynomorium | Cynomorium songaricum |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0284 | Nan She Teng | 南蛇藤 | Oriental bittersweet | Celastrus orbiculatus |
| H0343 | Qing Hao Zi | 青蒿子 | sweet wormwood | Artemisia carvifolia |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0166 | Long Kui | 龙葵 | Black nightshade | Solanum nigrum |
| H0989 | Ding Kui Cao | 丁葵草 | Herb of twinleaf zornia | Kummerowia striata |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0237 | Mei Gui Hua | 玫瑰花 | Rugose rose flower | Rosa rugosa |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0777 | Zao Jia | 皂荚 | Chinese honeylocust | Gleditsia sinensis |
| H0793 | Zhao Shan Bai | 照山白 | Manchurian rhododendron | Rhododendron micranthum |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0220 | Man Shan Hong You | 满山红油 | Daurian rhododendron oil | Oleum rhododendri daurici |
| H0361 | Ren Zi Cao | 人字草 | Herb of twinleaf zornia | Kummerowia striata |
| H0068 | Jin Ying Zi Rou | 金樱子肉 | Cherokee rose seed | Rosa laevigata |
| H0925 | Da Fu Zi | 大腹子 | Areca palm | Areca catechu |
| H1214 | Hua Jiao | 花椒 | Bunge pricklyash | Zanthoxylum bungeanum |
| H0779 | Zao Jiao Zhen | 皂角针 | Chinese honeylocust spine | Gleditsia sinensis |
| H0363 | Rong Shu Ye | 榕树叶 | Banyan | Ficus microcarpa |
| H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |
| H0408 | Bing Lang | 槟榔 | Betenutpalm | Areca catechu |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0532 | Teng Huang | 藤黄 | Gamboge tree resin | Garcinia morella |
| H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
| H0626 | Xi Nan Huang Qin | 西南黄芩 | Yunnan skullcap | Scutellaria amoena |
| H0534 | Teng Li Gen | 藤梨根 | NA | Actinidia arguta |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H1102 | Gu Sui Bu | 骨碎补 | Fortune’s drynaria rhizome | Drynaria fortunei |
| H0472 | Shu Da Huang | 熟大黄 | NA | Rheum palmatum |
| H1217 | Bai Mei Hua | 白梅花 | Japanese apricot flower | Prunus mume |
| H1213 | Hu Zhang | 虎杖 | Japanese fleeceflower | Polygonum cuspidatum |
| H0226 | Man Yue Mei | 蔓越莓 | Cranberry | Vaccinium oxycoccos |
| H1212 | Hu Ye Gan Jin Gao | 槲叶干浸膏 | NA | Quercus dentata |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0053 | Jin Lian Hua | 金莲花 | Chinese globeflower | Trollius chinensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H1141 | Guo Gang Long Jin Gao | 过岗龙浸膏 | NA | Entada phaseoloides |
| H0698 | Ya Zao | 牙皂 | Chinese honeylocust abnormal fruit | Gleditsia sinensis |
| H1211 | Bai Mei | 白眉 | pilose gerbera herb | Gerbera piloselloides |
| H0067 | Jin Ying Zi | 金樱子 | Cherokee rose seed | Rosa laevigata |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
| H1009 | Du Huo | 独活 | Doubleteeth pubescent angelica | Angelica pubescens |
| H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
| H0939 | Da Xue Teng | 大血藤 | Sargentgloryvine | Sargentodoxa cuneata |
| H0056 | Jin Qiao Mai | 金荞麦 | Wild buckwheat rhizome | Rhizoma fagopyri cymosi |
| H0602 | Wu Mei Rou | 乌梅肉 | Ebony | Prunus mume |
| H0819 | Zhi Zi Jin Gao | 栀子浸膏 | Cape jasmine fruit | Gardenia jasminoides |
| H0069 | Jin Ying Zi Ti Qu Ye | 金樱子提取液 | Cherokee rose seed | Rosa laevigata |
| H0007 | Huo Xue Teng | 活血藤 | NA | Sargentodoxa cuneata |
| H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
| H1061 | Bai He | 百合 | Lily | Lilium brownii |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0120 | Ban Bian Qi | 半边旗 | pinnated brake herb | Pteris semipinnata |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
| H0457 | Shi Er | 石耳 | Rock-Ears | Umbilicaria esculenta |