Herb Description
| Herb ID: H0433 | Chinese Character: 蛇麻子 |
| English Name: Common cnidium fruit | Latin Name: Cnidium monnieri |
| Chinese Pin Yin : She Ma Zi | TCM-ID: TCMH1872 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 72)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
2 Reference(s) |
| T12BGL | Cytochrome P450 2A6 | CYP2A6 |
P11509 |
2 Reference(s) |
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
4 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
| T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
| T31JL4 | Melanocyte-stimulating hormone receptor | MC1R |
Q01726 |
2 Reference(s) |
| T43GWF | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 | PPIP5K1 |
Q6PFW1 |
1 Reference(s) |
| T70U24 | Sigma non-opioid intracellular receptor 1 | SIGMAR1 |
Q99720 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
4 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
8 Reference(s) |
| T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY |
P01303 |
1 Reference(s) |
| T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
1 Reference(s) |
| T36NQ9 | Mothers against decapentaplegic homolog 1 | SMAD1 |
Q15797 |
1 Reference(s) |
| T56MD7 | Glutathione hydrolase 5 proenzyme | GGT5 |
P36269 |
1 Reference(s) |
| T87DEX | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | XDH |
P47989 |
1 Reference(s) |
| T48J1U | Aldo-keto reductase family 1 member C1 | AKR1C1 |
Q04828 |
1 Reference(s) |
| T46AQJ | Glutathione S-transferase P | GSTP1 |
P09211 |
1 Reference(s) |
| T53QS9 | Glutamate--cysteine ligase catalytic subunit | GCLC |
P48506 |
1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
1 Reference(s) |
| T05WWN | Corticoliberin | CRH |
P06850 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
2 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
4 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
3 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
| T77M4W | Adenosine receptor A2a | ADORA2A |
P29274 |
1 Reference(s) |
| T44FET | Cytochrome P450 2B10 | Cyp2b10 |
P12791 |
1 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
2 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
1 Reference(s) |
| T88P76 | DNA excision repair protein ERCC-1 | ERCC1 |
P07992 |
1 Reference(s) |
| T77OVM | Diablo homolog, mitochondrial | DIABLO |
Q9NR28 |
1 Reference(s) |
| T36SCD | NA | MIR107 |
NA |
1 Reference(s) |
| T20IHC | Diacylglycerol O-acyltransferase 1 | DGAT1 |
O75907 |
1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
1 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
2 Reference(s) |
| T01E8J | Amyloid-beta precursor protein | APP |
P05067 |
1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
2 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
3 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
2 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
1 Reference(s) |
| T62F1Y | Glutathione S-transferase A2 | GSTA2 |
P09210 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
| T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
| T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
1 Reference(s) |
| T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
| T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
| T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T05O6O | Estrogen receptor beta | ESR2 |
Q92731 |
1 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
1 Reference(s) |
| T02IOG | Cyclin-dependent kinase inhibitor 1B | CDKN1B |
P46527 |
1 Reference(s) |
| T84FSA | Forkhead box protein O3 | FOXO3 |
O43524 |
1 Reference(s) |
| T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
1 Reference(s) |
| T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
2 Reference(s) |
Related Compounds (Total: 13)
C1173
Name: Bergapten
C0214
Name: Methoxsalen
C0271
Name: Osthole
C1259
Name: Coumarin
C0285
Name: Palmitic Acid
key description of the interaction between compound and target