Target Description

Type Detail
Target ID T04TXM
Protein Name Regucalcin
Uniprot ID Q15493
Protein Name Alias RC;  Gluconolactonase;  GNL;  EC 3.1.1.17;  Senescence marker protein 30;  SMP-30
Gene ID 9104
Gene Symbol RGN
Gene Alias SMP30
TTD T93223: Research target
Pfam PF08450
GO
0030234:enzyme regulator activity

0004341:gluconolactonase activity

0005634:nucleus

0005829:cytosol

1901671:positive regulation of superoxide dismutase activity

0032515:negative regulation of phosphoprotein phosphatase activity

0097421:liver regeneration

0032781:positive regulation of ATPase activity

0008270:zinc ion binding

0034260:negative regulation of GTPase activity

0019853:L-ascorbic acid biosynthetic process

0043066:negative regulation of apoptotic process

0010867:positive regulation of triglyceride biosynthetic process

1901896:positive regulation of ATPase-coupled calcium transmembrane transporter activity

1902679:negative regulation of RNA biosynthetic process

0007283:spermatogenesis

2000279:negative regulation of DNA biosynthetic process

1901318:negative regulation of flagellated sperm motility

0050680:negative regulation of epithelial cell proliferation

0045019:negative regulation of nitric oxide biosynthetic process

0006874:cellular calcium ion homeostasis

1903625:negative regulation of DNA catabolic process

1903611:negative regulation of calcium-dependent ATPase activity

1903011:negative regulation of bone development

1903052:positive regulation of proteolysis involved in cellular protein catabolic process

0010907:positive regulation of glucose metabolic process

0006469:negative regulation of protein kinase activity

1903634:negative regulation of leucine-tRNA ligase activity

0043547:positive regulation of GTPase activity

0051344:negative regulation of cyclic-nucleotide phosphodiesterase activity

0045723:positive regulation of fatty acid biosynthetic process

0007568:aging

0050848:regulation of calcium-mediated signaling

0010922:positive regulation of phosphatase activity

0005737:cytoplasm

0001822:kidney development

0005509:calcium ion binding

1903629:positive regulation of dUTP diphosphatase activity

PDB 4GNC ; 3G4H ; 4GNB ; 3G4E
Drugbank DB14481 ; DB11348 ; DB11093
KEGG hsa:9104

Related Compounds  (Total: 2)

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C0899
Name: Andrographolide
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C0948
Name: aldosterone


Related Herbs  (Total: 11)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H0890 Chuan Xin Lian Nong Suo Ye穿心莲浓缩液 Common andrographisAndrographis paniculata
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H0886 Chuan Xin Lian穿心莲 Common andrographisAndrographis paniculata
H0887 Chuan Xin Lian Gan Jin Gao穿心莲干浸膏 Common andrographisAndrographis paniculata
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0889 Chuan Xin Lian Jin Gao穿心莲浸膏 Common andrographisAndrographis paniculata