Compound Description
| ID: C0163 | Common name: Juglone |
| IUPAC: 5-hydroxynaphthalene-1,4-dione | CAS: CAS:481-39-0 |
| Chembl ID: CHEMBL43612 | Pubchem ID: CID:3806 |
| Formula: C10H6O3 | TCM-ID: TCMC1427 |
| Smiles: C1=CC2=C(C(=O)C=CC2=O)C(=C1)O | |
| Alias:
1,4-Naphthoquinone, 5-hydroxy-;
Juglone; 5-Hydroxy-1,4-naphthalenedione; 1,4-Dihydro-1,4-dioxo-5-hydroxynaphthalene; 5-Hydroxy-1,4-naphthoquinone; 5-Hydroxynaphthoquinone; 8-Hydroxy-1,4-naphthoquinone; Akhnot; C.I. 75500; C.I. Natural Brown 7; Juglon; NSC 153189; NSC 34266; NSC 622948; Natural Brown 7; Nucin; Regianin; Walnut Extract |
Structure:
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Related Targets (Total: 7)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T20OEM | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | PIN1 |
Q13526 |
A | 5 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
B | 1 Reference(s) |
| T87UKX | Glucose-6-phosphate 1-dehydrogenase | G6PD |
P11413 |
B | 1 Reference(s) |
| T12WTT | Interleukin-5 | IL5 |
P05113 |
B | 1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
B | 1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
B | 1 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 6)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1221 | Hua Xiang Shu Guo Xu | 化香树果序 | NA | Platycarya strobilacea |
| H1168 | He Tao Ren | 核桃仁 | English walnut seed | Semen juglandis |
| H1220 | Hua Xiang Shu Guo | 化香树果 | NA | Platycarya strobilacea |
| H1167 | He Tao | 核桃 | English walnut seed | Semen juglandis |
| H0562 | Tou Gu Cao | 透骨草 | Tuberculate speranskia | Speranskia tuberculata |
| H0002 | Hui Xiang | 茴香 | Fennel fruit | Foeniculum vulgare |
Ckey description of the interaction between compound and target