Target Description

Type Detail
Target ID T80L9F
Protein Name Complement C5
Uniprot ID P01031
Protein Name Alias C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
Gene ID 727
Gene Symbol C5
Gene Alias CPAMD4
TTD T60708: Successful target
Pfam PF01821 ; PF17789 ; PF07677 ; PF17791 ; PF00207 ; PF01835 ; PF07678 ; PF17790 ; PF01759 ; PF07703
GO
0005615:extracellular space

0019835:cytolysis

0005579:membrane attack complex

0032722:positive regulation of chemokine production

0030449:regulation of complement activation

0007186:G protein-coupled receptor signaling pathway

0005102:signaling receptor binding

0010575:positive regulation of vascular endothelial growth factor production

0006957:complement activation, alternative pathway

0005576:extracellular region

0007166:cell surface receptor signaling pathway

0008009:chemokine activity

0001701:in utero embryonic development

0045766:positive regulation of angiogenesis

0010760:negative regulation of macrophage chemotaxis

0006958:complement activation, classical pathway

0006935:chemotaxis

0004866:endopeptidase inhibitor activity

0006954:inflammatory response

0070062:extracellular exosome

0000187:activation of MAPK activity

0006956:complement activation

PDB 3KLS ; 4E0S ; 5B71 ; 1KJS ; 3HQA ; 5HCC ; 3CU7 ; 5I5K ; 6H04 ; 5HCD ; 6H03 ; 1CFA ; 3KM9 ; 4UU9 ; 4P39 ; 3PRX ; 4A5W ; 5HCE ; 3HQB ; 5B4P ; 3PVM ; 1XWE ; 6RPT
Drugbank DB09130 ; DB14533 ; DB11580 ; DB00028 ; DB01593 ; DB01257 ; DB14548 ; DB14487
KEGG hsa:727

Related Compounds  (Total: 1)

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C0374
Name: Rosmarinic Acid


Related Herbs  (Total: 18)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0612 Cao Shan Hu Jin Gao草珊瑚浸膏 NASarcandra glabra
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H0614 Wu Zhao Long五爪龙 Cairo morninggloryIpomoea cairica
H0496 Shui Ze Lan水泽兰 NALycopus lucidus
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0083 Jiu Jie Cha九节茶 Glabrous sarcandraSarcandra glabra
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0632 Xia Ku Cao夏枯草 Common selfhealPrunella vulgaris
H0002 Hui Xiang茴香 Fennel fruitFoeniculum vulgare
H0219 Man Shan Hong满山红 Dahurian rhododendronRhododendron dauricum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0673 Xin Jiang Zi Cao新疆紫草 Arnebia rootArnebia euchroma
H0074 Jing Jie Tan荆芥炭 NASchizonepetae herba