HIT-result

Type	Detail
Target ID	T19YQS
Protein Name	Complement C3
Uniprot ID	P01024
Protein Name Alias	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Gene ID	718
Gene Symbol	C3
Gene Alias	CPAMD1
TTD	T26851: Clinical Trial target
Pfam	PF01821 ; PF17789 ; PF07677 ; PF17791 ; PF00207 ; PF01835 ; PF07678 ; PF17790 ; PF01759 ; PF07703
GO	0150062:complement-mediated synapse pruning 0072562:blood microparticle 0070062:extracellular exosome 0097278:complement-dependent cytotoxicity 0035846:oviduct epithelium development 0016322:neuron remodeling 0032991:protein-containing complex 0010828:positive regulation of glucose transmembrane transport 0005615:extracellular space 0009986:cell surface 0150064:vertebrate eye-specific patterning 0044267:cellular protein metabolic process 0030449:regulation of complement activation 0001970:positive regulation of activation of membrane attack complex 0007186:G protein-coupled receptor signaling pathway 0005102:signaling receptor binding 1905114:cell surface receptor signaling pathway involved in cell-cell signaling 0001934:positive regulation of protein phosphorylation 0010884:positive regulation of lipid storage 0048260:positive regulation of receptor-mediated endocytosis 0010575:positive regulation of vascular endothelial growth factor production 0050776:regulation of immune response 0006957:complement activation, alternative pathway 0045745:positive regulation of G protein-coupled receptor signaling pathway 0005576:extracellular region 0097242:amyloid-beta clearance 0035578:azurophil granule lumen 0005886:plasma membrane 0043687:post-translational protein modification 0035590:purinergic nucleotide receptor signaling pathway 0009617:response to bacterium 0010866:regulation of triglyceride biosynthetic process 0006631:fatty acid metabolic process 0031715:C5L2 anaphylatoxin chemotactic receptor binding 0043312:neutrophil degranulation 0060100:positive regulation of phagocytosis, engulfment 0001798:positive regulation of type IIa hypersensitivity 0045766:positive regulation of angiogenesis 2000427:positive regulation of apoptotic cell clearance 0034774:secretory granule lumen 0006955:immune response 0006958:complement activation, classical pathway 0004866:endopeptidase inhibitor activity 0006954:inflammatory response 0005788:endoplasmic reticulum lumen 0006956:complement activation 0007165:signal transduction
PDB	2I07 ; 6RUV ; 1C3D ; 2GOX ; 5FOA ; 4ONT ; 6EHG ; 2XWJ ; 2WIN ; 3OXU ; 4ZH1 ; 6RMU ; 3D5S ; 4M76 ; 3D5R ; 5FOB ; 5FO9 ; 3T4A ; 3G6J ; 2XWB ; 5O35 ; 2ICF ; 6RUR ; 3OED ; 4HWJ ; 5FO7 ; 1W2S ; 6RMT ; 6S0B ; 4HW5 ; 2WY7 ; 2XQW ; 5FO8 ; 1GHQ ; 2A73 ; 2WII ; 2WY8 ; 3L5N ; 5O32 ; 3OHX ; 3RJ3 ; 4I6O ; 2QKI ; 2ICE ; 5NBQ ; 3NMS ; 2A74 ; 3L3O ; 2NOJ
Drugbank	DB09130 ; DB14533 ; DB00028 ; DB14487 ; DB06492 ; DB01593 ; DB14548 ; DB01915
KEGG	hsa:718

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Name: Rosmarinic Acid

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Name: Triptolide

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0612	Cao Shan Hu Jin Gao	草珊瑚浸膏	NA	Sarcandra glabra
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0632	Xia Ku Cao	夏枯草	Common selfheal	Prunella vulgaris
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0673	Xin Jiang Zi Cao	新疆紫草	Arnebia root	Arnebia euchroma
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0496	Shui Ze Lan	水泽兰	NA	Lycopus lucidus
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0118	Kun Ming Shan Hai Tang	昆明山海棠	Glaucousback threewingnut	Tripterygium hypoglaucum
H0002	Hui Xiang	茴香	Fennel fruit	Foeniculum vulgare
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H0074	Jing Jie Tan	荆芥炭	NA	Schizonepetae herba
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H0614	Wu Zhao Long	五爪龙	Cairo morningglory	Ipomoea cairica
H0083	Jiu Jie Cha	九节茶	Glabrous sarcandra	Sarcandra glabra
H0219	Man Shan Hong	满山红	Dahurian rhododendron	Rhododendron dauricum