HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T27LA6	DNA	DNMT1	P26358	1 Reference(s)
T01JSX	Carbonyl reductase [NADPH] 1	CBR1	P16152	1 Reference(s)
T74JJN	Fatty acid synthase	FASN	P49327	2 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	3 Reference(s)
T43N2D	Epidermal growth factor receptor	EGFR	P00533	1 Reference(s)
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	1 Reference(s)
T69ESY	Ras GTPase-activating protein-binding protein 1	G3BP1	Q13283	1 Reference(s)
T18LX5	Neutrophil elastase	ELANE	P08246	1 Reference(s)
T54SZZ	Endoplasmic reticulum chaperone BiP	HSPA5	P11021	1 Reference(s)
T92FAW	Dual specificity protein phosphatase 1	DUSP1	P28562	1 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	1 Reference(s)
T14LSK	E3 ubiquitin-protein ligase XIAP	XIAP	P98170	1 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	2 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	1 Reference(s)
T73LXA	Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1B	HSPA1A;HSPA1B	P0DMV8;P0DMV9	1 Reference(s)
T46K2X	Heat shock 70 kDa protein 4	HSPA4	P34932	2 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	4 Reference(s)
T04OVZ	Cyclin-A1	CCNA1	P78396	1 Reference(s)
T39KTX	General transcription and DNA repair factor IIH helicase subunit XPB	ERCC3	P19447	1 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	1 Reference(s)
T09BRP	NA	PKB_RS07820	NA	1 Reference(s)
T47H3O	Heat shock protein HSP 90-alpha	HSP90AA1	P07900	1 Reference(s)
T40JZG	GPI-anchor transamidase	PIGK	Q92643	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	2 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	2 Reference(s)
T00T9M	Thrombospondin-1	THBS1	P07996	1 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	2 Reference(s)
T74LFK	Neurogenic locus notch homolog protein 1	NOTCH1	P46531	1 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	2 Reference(s)
T81BH5	Sulfotransferase 1A1	SULT1A1	P50225	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	1 Reference(s)
T37VLU	Interferon gamma	IFNG	P01579	2 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	2 Reference(s)
T32PI2	Programmed cell death 1 ligand 1	CD274	Q9NZQ7	2 Reference(s)
T67HAF	Signal transducer and activator of transcription 1-alpha/beta	STAT1	P42224	1 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	1 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	2 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	3 Reference(s)
T87Y6K	T-cell surface glycoprotein CD1a	CD1A	P06126	1 Reference(s)
T11R4S	Tumor necrosis factor receptor superfamily member 5	CD40	P25942	2 Reference(s)
T23OTN	T-lymphocyte activation antigen CD80	CD80	P33681	1 Reference(s)
T47MPW	T-lymphocyte activation antigen CD86	CD86	P42081	1 Reference(s)
T08OEP	Monocyte differentiation antigen CD14	CD14	P08571	1 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	2 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	1 Reference(s)
T02P7Q	Dihydrofolate reductase	DHFR	P00374	1 Reference(s)
T84VZG	Ryanodine receptor 1	RYR1	P21817	1 Reference(s)
T84P70	Urokinase-type plasminogen activator	PLAU	P00749	2 Reference(s)
T60A9R	NA	CYP3A	NA	1 Reference(s)
T17UP9	C-C motif chemokine 2	CCL2	P13500	1 Reference(s)
T06MXL	Neprilysin	MME	P08473	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	1 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	1 Reference(s)
T34DZ7	Interleukin-2	IL2	P60568	1 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	1 Reference(s)
T64W2K	Cyclin-dependent kinase inhibitor 1	CDKN1A	P38936	1 Reference(s)
T50V79	Interleukin-4	IL4	P05112	1 Reference(s)
T51AX1	Interleukin-23 subunit alpha	IL23A	Q9NPF7	1 Reference(s)
T30A57	C-C chemokine receptor type 7	CCR7	P32248	1 Reference(s)
T75HMM	Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1	Q07820	1 Reference(s)
T19YQS	Complement C3	C3	P01024	1 Reference(s)
T56NC7	Beta-defensin 4A	DEFB4A; DEFB4B	O15263	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	1 Reference(s)
T13DHC	Disintegrin and metalloproteinase domain-containing protein 10	ADAM10	O14672	1 Reference(s)
T64X48	C-X-C chemokine receptor type 4	CXCR4	P61073	1 Reference(s)
T70YKV	Baculoviral IAP repeat-containing protein 3	BIRC3	Q13489	1 Reference(s)
T94H37	Cadherin-1	CDH1	P12830	1 Reference(s)
T09KPZ	Vimentin	VIM	P08670	1 Reference(s)
T98RXH	Focal adhesion kinase 1	PTK2	Q05397	1 Reference(s)
T60DK9	Rho-associated protein kinase 1	ROCK1	Q13464	1 Reference(s)
T11BL5	Serine/threonine-protein kinase Chk1	CHEK1	O14757	1 Reference(s)
T29B10	Interleukin-17A	IL17A	Q16552	1 Reference(s)
T78MPR	Synaptophysin	SYP	P08247	1 Reference(s)
T99ARN	Forkhead box protein P3	FOXP3	Q9BZS1	1 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T30L86	Tumor necrosis factor receptor superfamily member 10B	TNFRSF10B	O14763	1 Reference(s)
T09KQF	Proliferating cell nuclear antigen	PCNA	P12004	1 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	1 Reference(s)
T86VPJ	NA	MIR224	NA	1 Reference(s)
T49XOZ	Krueppel-like factor 7	KLF7	O75840	1 Reference(s)

Herb ID: H0118	Chinese Character: 昆明山海棠
English Name: Glaucousback threewingnut	Latin Name: Tripterygium hypoglaucum
Chinese Pin Yin : Kun Ming Shan Hai Tang	TCM-ID: TCMH1227
Therapeutic Function in Chinese : NA	Therapeutic Function in English: NA
Herb Function: NA

Herb Description

Related Targets (Total: 83)

Related Compounds (Total: 3)