ID: C0046 | Common name: Epigallocatechin |
IUPAC: (2R,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | CAS: CAS:970-74-1 |
Chembl ID: CHEMBL47386 | Pubchem ID: CID:72277 |
Formula: C15H14O7 | TCM-ID: TCMC1117 |
Smiles: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O | |
Alias:
2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-, (2R-cis)-;
Epigallocatechol; Gallocatechol, l-; (2R,3R)-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol; (-)-3,3',4',5,5',7-Flavanhexol; (-)-Epigallocatechin; (-)-Epigallocatechol; (-)-epi-Gallocatechin; (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,5,7-trihydroxychroman; 1-epi-3',4',5',5,7-Pentahydroxy-3-flavanol; 3,3',4',5,5',7-Flavanhexol; Antiscurvy factor C2; EGC; Epigallocatechin; Factor C2 (antiscurvy); Galloepicatechin; L-Epigallocatechin; NSC 674039; Sunphenon EGC; epi-Gallocatechin; l-Epigallocatechin; l-Epigallocatechol |
Structure: |
Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
---|---|---|---|---|---|
T27LA6 | DNA | DNMT1 |
P26358 |
A | 1 Reference(s) |
T01JSX | Carbonyl reductase [NADPH] 1 | CBR1 |
P16152 |
A | 1 Reference(s) |
T74JJN | Fatty acid synthase | FASN |
P49327 |
A | 1 Reference(s) |
T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
A | 1 Reference(s) |
T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
A | 1 Reference(s) |
T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
A | 1 Reference(s) |
T69ESY | Ras GTPase-activating protein-binding protein 1 | G3BP1 |
Q13283 |
A | 1 Reference(s) |
T18LX5 | Neutrophil elastase | ELANE |
P08246 |
A | 1 Reference(s) |
T54SZZ | Endoplasmic reticulum chaperone BiP | HSPA5 |
P11021 |
A | 1 Reference(s) |
T54CIF | Interleukin-8 | CXCL8 |
P10145 |
B | 1 Reference(s) |
T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
B | 1 Reference(s) |
T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
B | 1 Reference(s) |
T81BH5 | Sulfotransferase 1A1 | SULT1A1 |
P50225 |
B | 1 Reference(s) |
T84VZG | Ryanodine receptor 1 | RYR1 |
P21817 |
C | 1 Reference(s) |
T84P70 | Urokinase-type plasminogen activator | PLAU |
P00749 |
C | 1 Reference(s) |
T60A9R | NA | CYP3A |
NA |
C | 1 Reference(s) |
T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
C | 1 Reference(s) |
T06MXL | Neprilysin | MME |
P08473 |
C | 1 Reference(s) |
T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
C | 1 Reference(s) |
T85U8U | Caspase-3 | CASP3 |
P42574 |
C | 1 Reference(s) |
Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
---|---|---|---|---|
H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
H0721 | Yang Mei Gen | 杨梅根 | Myrica rubra sieb. et zucc | Myrica rubra |
H0342 | Qing Hao | 青蒿 | sweet wormwood | Artemisia carvifolia |
H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
H0818 | Zhi Zi | 栀子 | Cape jasmine fruit | Gardenia jasminoides |
H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
H0692 | Xue Ren Shen | 血人参 | NA | Lespedeza bicolor |
H0020 | Ji Yan Cao | 鸡眼草 | Striate kummerowia | Kummerowia striata |
H0424 | Shan Zhi | 山栀 | Cape jasmine | Gardenia jasminoides |
H0457 | Shi Er | 石耳 | Rock-Ears | Umbilicaria esculenta |
H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
H1004 | Bai Cha | 白茶 | White tea | Camellia sinensis |
H0181 | Luo Bu Ma | 罗布麻 | Dogbane | Apocynum venetum |
H0819 | Zhi Zi Jin Gao | 栀子浸膏 | Cape jasmine fruit | Gardenia jasminoides |
H1211 | Bai Mei | 白眉 | pilose gerbera herb | Gerbera piloselloides |
H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
H0229 | Mao Da Ding Cao | 毛大丁草 | Pilose gerbera | Gerbera piloselloides |
H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
H0343 | Qing Hao Zi | 青蒿子 | sweet wormwood | Artemisia carvifolia |
H0637 | Cha Ye | 茶叶 | Common tea | Camellia sinensis |
H0053 | Jin Lian Hua | 金莲花 | Chinese globeflower | Trollius chinensis |
H0989 | Ding Kui Cao | 丁葵草 | Herb of twinleaf zornia | Kummerowia striata |
H0361 | Ren Zi Cao | 人字草 | Herb of twinleaf zornia | Kummerowia striata |
H1141 | Guo Gang Long Jin Gao | 过岗龙浸膏 | NA | Entada phaseoloides |
H1140 | Guo Gang Long | 过岗龙 | NA | Entada phaseoloides |
H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
H0118 | Kun Ming Shan Hai Tang | 昆明山海棠 | Glaucousback threewingnut | Tripterygium hypoglaucum |
H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
H0166 | Long Kui | 龙葵 | Black nightshade | Solanum nigrum |