ID: C0369 | Common name: Rhein |
IUPAC: 4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid | CAS: CAS:478-43-3 |
Chembl ID: CHEMBL418068 | Pubchem ID: CID:10168 |
Formula: C15H8O6 | TCM-ID: TCMC2014 |
Smiles: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)C(=O)O | |
Alias:
2-Anthraquinonecarboxylic acid, 4,5-dihydroxy-;
2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-; 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid; 1,8-Dihydroxy-3-carboxyanthraquinone; 1,8-Dihydroxyanthraquinone-3-carboxylic acid; 4,5-Dihydroxy-2-anthraquinonecarboxylic acid; Cassic acid; Chrysazin-3-carboxylic acid; Monorhein; NSC 38629; Rheic acid; Rhein; Rheinic acid; Rhubarb yellow |
Structure: |
Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
---|---|---|---|---|---|
T26CFB | DNA damage-inducible transcript 3 protein | DDIT3 |
P35638;P0DPQ6 |
A | 1 Reference(s) |
T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
A | 1 Reference(s) |
T55L5P | Macrophage scavenger receptor types I and II | MSR1 |
P21757 |
A | 1 Reference(s) |
T08U92 | Mitochondrial brown fat uncoupling protein 1 | UCP1 |
P25874 |
A | 1 Reference(s) |
T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
A | 1 Reference(s) |
T46YMA | Ras-related C3 botulinum toxin substrate 1 | RAC1 |
P63000 |
A | 1 Reference(s) |
T85U8U | Caspase-3 | CASP3 |
P42574 |
A | 1 Reference(s) |
T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
A | 1 Reference(s) |
T26KIE | Transcription factor AP-1 | JUN |
P05412 |
B | 1 Reference(s) |
T96DNP | Nucleic acid dioxygenase ALKBH1 | ALKBH1 |
Q13686 |
B | 1 Reference(s) |
T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
B | 1 Reference(s) |
T13HYI | Alpha-ketoglutarate-dependent dioxygenase FTO | FTO |
Q9C0B1 |
B | 1 Reference(s) |
T75EH8 | Glucagon-like peptide 1 receptor | GLP1R |
P43220 |
C | 1 Reference(s) |
T91UNL | Keratin, type I cytoskeletal 14 | KRT14 |
P02533 |
C | 1 Reference(s) |
T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
C | 1 Reference(s) |
T23VMI | Tumor necrosis factor | TNF |
P01375 |
C | 1 Reference(s) |
Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
---|---|---|---|---|
H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |
H0102 | Jue Ming Zi | 决明子 | Sickle senna seed | Cassia tora |
H1000 | Dong Gua Zi | 冬瓜子 | Chinese waxgourd seed | Benincasa hispida |
H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
H0632 | Xia Ku Cao | 夏枯草 | Common selfheal | Prunella vulgaris |
H0472 | Shu Da Huang | 熟大黄 | NA | Rheum palmatum |
H1011 | Bai Chou | 白丑 | Pharbitis seed | Semen pharbitidis |
H1166 | He Shou Wu | 何首乌 | Tuber fleeceflower | Polygonum multiflorum |
H1173 | Hei Chou | 黑丑 | Pharbitis seed | Semen pharbitidis |
H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
H0387 | San Ya Ku | 三桠苦 | Common rue | Ruta graveolens |
H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
H1213 | Hu Zhang | 虎杖 | Japanese fleeceflower | Polygonum cuspidatum |
H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |
H0774 | Yun Xiang Jin Gao | 芸香浸膏 | Ruta | Ruta graveolens |
H0540 | Tian Ji Huang | 田基黄 | all - grass of japanese st. johnswort | Grangea maderaspatana |
H0998 | Dong Gua Pi | 冬瓜皮 | Chinese waxgourd peel | Benincasa hispida |
H0685 | Xuan Cao Gen | 萱草根 | Orange daylily | Hemerocallis fulva |