Target Description

Type Detail
Target ID T71BV3
Protein Name Glutathione peroxidase 1
Uniprot ID P07203
Protein Name Alias GPx-1;  GSHPx-1;  EC 1.11.1.9;  Cellular glutathione peroxidase
Gene ID 2876
Gene Symbol GPX1
Gene Alias NA
TTD T70654: Research target
Pfam PF00255
GO
0033599:regulation of mammary gland epithelial cell proliferation

0045454:cell redox homeostasis

0042542:response to hydrogen peroxide

0048741:skeletal muscle fiber development

0004602:glutathione peroxidase activity

0005829:cytosol

0006641:triglyceride metabolic process

0018158:protein oxidation

0010269:response to selenium ion

0001885:endothelial cell development

0034599:cellular response to oxidative stress

0043403:skeletal muscle tissue regeneration

0019369:arachidonic acid metabolic process

0051897:positive regulation of protein kinase B signaling

0009650:UV protection

0045444:fat cell differentiation

0090201:negative regulation of release of cytochrome c from mitochondria

0010332:response to gamma radiation

0005759:mitochondrial matrix

0042311:vasodilation

0009609:response to symbiotic bacterium

0001659:temperature homeostasis

0002862:negative regulation of inflammatory response to antigenic stimulus

1902042:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

0007605:sensory perception of sound

0017124:SH3 domain binding

1902905:positive regulation of supramolecular fiber organization

0019372:lipoxygenase pathway

0051450:myoblast proliferation

0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0033194:response to hydroperoxide

0004601:peroxidase activity

0060055:angiogenesis involved in wound healing

0047066:phospholipid-hydroperoxide glutathione peroxidase activity

0006195:purine nucleotide catabolic process

0005739:mitochondrion

0005737:cytoplasm

0040029:regulation of gene expression, epigenetic

1902176:negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

0061136:regulation of proteasomal protein catabolic process

0043534:blood vessel endothelial cell migration

0042744:hydrogen peroxide catabolic process

0051702:biological process involved in interaction with symbiont

0060047:heart contraction

0006749:glutathione metabolic process

0009410:response to xenobiotic stimulus

PDB 2F8A
Drugbank DB09061 ; DB14011 ; DB14009 ; DB00143 ; DB11091 ; DB11127 ; DB09221 ; DB03310 ; DB11590
KEGG hsa:2876

Related Compounds  (Total: 3)

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C0430
Name: Taurine
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C0475
Name: Ursodiol
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C0561
Name: Taurine


Related Herbs  (Total: 11)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H0352 Quan Xie全蝎 ScorpionButhus martensi
H0943 Dan Cai淡菜 MusselMytilus edulis
H0736 Yi Dian Hong一点红 Sowthistle tasselflowerEmilia sonchifolia
H0850 Zi Su Ye紫苏叶 Common perilla leafPerilla frutescens var. arguta
H0095 Gou Qi Zi枸杞子 Chinese wolfberry fruitLycium chinense
H1163 He Bao Cao荷包草 NALamprocapnos spectabilis
H0849 Zi Su Geng紫苏梗 Common perilla stemPerilla frutescens var. arguta
H0094 Gou Qi枸杞 Chinese wolfberry fruitLycium chinense
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens