HIT-result

Target Description

Type	Detail
Target ID	T17E95
Protein Name	Protein kinase C gamma type
Uniprot ID	P05129
Protein Name Alias	PKC-gamma; EC 2.7.11.13
Gene ID	5582
Gene Symbol	PRKCG
Gene Alias	PKCG
TTD	T47107: Successful target
Pfam	PF00130 ; PF00168 ; PF00433 ; PF00069
GO	0005634:nucleus 0060384:innervation 0106311:protein threonine kinase activity 0014069:postsynaptic density 0005829:cytosol 0044305:calyx of Held 0050764:regulation of phagocytosis 0030425:dendrite 0042752:regulation of circadian rhythm 0004672:protein kinase activity 0008270:zinc ion binding 0099171:presynaptic modulation of chemical synaptic transmission 0031397:negative regulation of protein ubiquitination 0043524:negative regulation of neuron apoptotic process 0004712:protein serine/threonine/tyrosine kinase activity 0048265:response to pain 0007611:learning or memory 0007635:chemosensory behavior 1990911:response to psychosocial stress 0106310:protein serine kinase activity 0006468:protein phosphorylation 0032095:regulation of response to food 0035556:intracellular signal transduction 0005524:ATP binding 0004698:calcium-dependent protein kinase C activity 0043278:response to morphine 2000300:regulation of synaptic vesicle exocytosis 0004697:protein kinase C activity 0007268:chemical synaptic transmission 0004674:protein serine/threonine kinase activity 0030168:platelet activation 0032425:positive regulation of mismatch repair 0018105:peptidyl-serine phosphorylation 1901799:negative regulation of proteasomal protein catabolic process 0005886:plasma membrane 0099523:presynaptic cytosol 0046777:protein autophosphorylation 0048511:rhythmic process 0042177:negative regulation of protein catabolic process 0097060:synaptic membrane 0005911:cell-cell junction 0099524:postsynaptic cytosol 0016310:phosphorylation 0048471:perinuclear region of cytoplasm
PDB	2UZP ; 2E73
Drugbank	DB12010 ; DB00675
KEGG	hsa:5582

Type

Detail

Target ID

T17E95

Protein Name

Protein kinase C gamma type

Uniprot ID

P05129

Protein Name Alias

PKC-gamma; EC 2.7.11.13

Gene ID

5582

Gene Symbol

PRKCG

Gene Alias

PKCG

TTD

T47107: Successful target

Pfam

PF00130 ; PF00168 ; PF00433 ; PF00069

0005634:nucleus

0060384:innervation

0106311:protein threonine kinase activity

0014069:postsynaptic density

0005829:cytosol

0044305:calyx of Held

0050764:regulation of phagocytosis

0030425:dendrite

0042752:regulation of circadian rhythm

0004672:protein kinase activity

0008270:zinc ion binding

0099171:presynaptic modulation of chemical synaptic transmission

0031397:negative regulation of protein ubiquitination

0043524:negative regulation of neuron apoptotic process

0004712:protein serine/threonine/tyrosine kinase activity

0048265:response to pain

0007611:learning or memory

0007635:chemosensory behavior

1990911:response to psychosocial stress

0106310:protein serine kinase activity

0006468:protein phosphorylation

0032095:regulation of response to food

0035556:intracellular signal transduction

0005524:ATP binding

0004698:calcium-dependent protein kinase C activity

0043278:response to morphine

2000300:regulation of synaptic vesicle exocytosis

0004697:protein kinase C activity

0007268:chemical synaptic transmission

0004674:protein serine/threonine kinase activity

0030168:platelet activation

0032425:positive regulation of mismatch repair

0018105:peptidyl-serine phosphorylation

1901799:negative regulation of proteasomal protein catabolic process

0005886:plasma membrane

0099523:presynaptic cytosol

0046777:protein autophosphorylation

0048511:rhythmic process

0042177:negative regulation of protein catabolic process

0097060:synaptic membrane

0005911:cell-cell junction

0099524:postsynaptic cytosol

0016310:phosphorylation

0048471:perinuclear region of cytoplasm

PDB

2UZP ; 2E73

Drugbank

DB12010 ; DB00675

KEGG

hsa:5582

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1096	Ge Hua	葛花	flower bud of lobed kudzuvine	Pueraria lobata
H0665	Chai Hu Shao	柴胡梢	Chinese thorowax	Bupleurum chinense
H0614	Wu Zhao Long	五爪龙	Cairo morningglory	Ipomoea cairica
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H0685	Xuan Cao Gen	萱草根	Orange daylily	Hemerocallis fulva
H0164	Ban Zhi Lian	半枝莲	Barbed skullcap	Scutellaria barbata
H0233	Mao Liang Mian Zhen	毛两面针	NA	Zanthoxylum nitidum
H1214	Hua Jiao	花椒	Bunge pricklyash	Zanthoxylum bungeanum
H1253	Huang Qin Jin Gao Fen	黄芩浸膏粉	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H0878	Ba Dou Shuang	巴豆霜	Defatted croton seed powder	Croton tiglium
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0941	Da Zao	大枣	Chinese date	Ziziphus jujuba
H1094	Ge Gen	葛根	Lobed kudzuvine root	Pueraria lobata
H0659	Chai Hu Jin Gao	柴胡浸膏	Chinese thorowax	Bupleurum chinense
H0650	Chai Hu	柴胡	Chinese thorowax	Bupleurum chinense
H1095	Ge Gen Gan Jin Gao	葛根干浸膏	Lobed kudzuvine root	Pueraria lobata
H0965	Deng Zhan Xi Xin	灯盏细辛	Shortscape fleabane	Erigeron breviscapus
H0869	Ba Dou	巴豆	Pu rging croton	Croton tiglium
H1254	Huang Qin Tan	黄芩炭	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H1163	He Bao Cao	荷包草	NA	Lamprocapnos spectabilis
H1037	Fen Ge	粉葛	Thomson kudzuvine	Pueraria thomsonii
H0714	Yan Tai Chai Hu	烟台柴胡	Chinese thorowax	Bupleurum chinense
H0310	Pian Qin	片芩	Scutellaria amoena	Scutellaria baicalensis
H1080	Gan Ge	干葛	Lobed kudzuvine root	Pueraria lobata
H1252	Huang Qin Jin Gao	黄芩浸膏	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H1251	Huang Qin	黄芩	Root of Baikal skullcaap	Scutellaria baicalensis

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 27)