Compound Description

ID:   C0395 Common name:   Scutellarin
IUPAC:  (2S,3S,4S,5R,6S)-6-[5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid CAS:  CAS:27740-01-8
Chembl ID:   CHEMBL487805 Pubchem ID:   CID:185617
Formula:  C21H18O12 TCM-ID:  TCMC2055
Smiles:  C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O)O
Alias:

Glucopyranosiduronic acid, 5,6-dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl, β-D-;

Scutellarin;

5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid;

Flavone, 4',5,6,7-tetrahydroxy-, 7-β-D-glucopyranuronoside;

Scutellarein 7-O-β-D-glucuronide;

Scutellarein 7-O-β-glucuronide;

Scutellarein 7-glucuronide;

Scutellarein 7-β-D-glucuronide;

Scutellarein 7-β-D-glucuronoside;

Scutellarin B
Structure:

Related Targets  (Total: 16)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T71BDH Mitogen-activated protein kinase 14MAPK14 Q16539
A 3 Reference(s)
T02QBS Cytochrome P450 1A2CYP1A2 P05177
A 1 Reference(s)
T88TDZ RAC-alpha serine/threonine-protein kinaseAKT1 P31749
A 1 Reference(s)
T85U8U Caspase-3CASP3 P42574
B 1 Reference(s)
T74I49 Bcl-2-like protein 1BCL2L1 Q07817
B 1 Reference(s)
T85NRC Pyruvate kinase PKMPKM P14618
B 1 Reference(s)
T20E5P Cytochrome b-245 heavy chainCYBB P04839
B 1 Reference(s)
T17E95 Protein kinase C gamma typePRKCG P05129
C 1 Reference(s)
T80TUC Apoptosis regulator BAXBAX Q07812
C 1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
C 1 Reference(s)
T16MRU NACHT, LRR and PYD domains-containing protein 3NLRP3 Q96P20
C 1 Reference(s)
T62P0D Collagenase 3MMP13 P45452
C 1 Reference(s)
T74LFK Neurogenic locus notch homolog protein 1NOTCH1 P46531
C 1 Reference(s)
T34U48 A disintegrin and metalloproteinase with thrombospondin motifs 5ADAMTS5 Q9UNA0
C 1 Reference(s)
T91D6X Protein Wnt-3aWNT3A P56704
C 1 Reference(s)
T79BDP Frizzled-7FZD7 O75084
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 10)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H1251 Huang Qin黄芩 Root of Baikal skullcaapScutellaria baicalensis
H0614 Wu Zhao Long五爪龙 Cairo morninggloryIpomoea cairica
H0310 Pian Qin片芩 Scutellaria amoenaScutellaria baicalensis
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H1253 Huang Qin Jin Gao Fen黄芩浸膏粉 Extract of root of Baikal skullcaapScutellaria baicalensis
H0965 Deng Zhan Xi Xin灯盏细辛 Shortscape fleabaneErigeron breviscapus
H1254 Huang Qin Tan黄芩炭 Extract of root of Baikal skullcaapScutellaria baicalensis
H1252 Huang Qin Jin Gao黄芩浸膏 Extract of root of Baikal skullcaapScutellaria baicalensis
H0164 Ban Zhi Lian半枝莲 Barbed skullcapScutellaria barbata