HIT-result

Type	Detail
Target ID	T49NJW
Protein Name	C-C motif chemokine 20
Uniprot ID	P78556
Protein Name Alias	Beta-chemokine exodus-1; CC chemokine LARC; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP-3-alpha; Small-inducible cytokine A20
Gene ID	6364
Gene Symbol	CCL20
Gene Alias	LARC; MIP3A; SCYA20
TTD	T04894: Clinical Trial target
Pfam	PF00048
GO	0002548:monocyte chemotaxis 0019221:cytokine-mediated signaling pathway 0072678:T cell migration 0035584:calcium-mediated signaling using intracellular calcium source 0030593:neutrophil chemotaxis 0006954:inflammatory response 0005615:extracellular space 0061844:antimicrobial humoral immune response mediated by antimicrobial peptide 0007165:signal transduction 0005576:extracellular region 0060326:cell chemotaxis 0071346:cellular response to interferon-gamma 0031640:killing of cells of other organism 0008009:chemokine activity 0072679:thymocyte migration 0042742:defense response to bacterium 0071356:cellular response to tumor necrosis factor 0070374:positive regulation of ERK1 and ERK2 cascade 0048247:lymphocyte chemotaxis 0031731:CCR6 chemokine receptor binding 0043547:positive regulation of GTPase activity 0007186:G protein-coupled receptor signaling pathway 0070098:chemokine-mediated signaling pathway 0071347:cellular response to interleukin-1 0006955:immune response 0006935:chemotaxis 0007267:cell-cell signaling 0048020:CCR chemokine receptor binding 2000406:positive regulation of T cell migration
PDB	6WWZ ; 5UR7 ; 1M8A ; 2JYO ; 2HCI
Drugbank	NA
KEGG	hsa:6364

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 1)