Compound Description
| ID: C0125 | Common name: Histamine |
| IUPAC: 2-(1H-imidazol-5-yl)ethanamine | CAS: CAS:51-45-6 |
| Chembl ID: CHEMBL90 | Pubchem ID: CID:774 |
| Formula: C5H9N3 | TCM-ID: TCMC1330 |
| Smiles: C1=C(NC=N1)CCN | |
| Alias:
1H-Imidazole-4-ethanamine;
Histamine; 2-(1H-Imidazol-4-yl)ethanamine; 2-(1H-Imidazol-4-yl)ethylamine; 2-(1H-Imidazol-5-yl)ethanamine; 2-(1H-Imidazol-5-yl)ethylamine; 2-(3H-Imidazol-4-yl)ethylamine; 2-(4-Imidazolyl)ethanamine; 2-(4-Imidazolyl)ethylamine; 4-(2-Aminoethyl)imidazole; 5-Imidazoleethylamine; Eramin; Ergamine; Ergotidine; Imidazole-4-ethylamine; NSC 33792; β-Imidazolyl-4-ethylamine |
Structure:
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Related Targets (Total: 9)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T05WWN | Corticoliberin | CRH |
P06850 |
A | 1 Reference(s) |
| T85RZS | Corticotropin-releasing factor receptor 1 | CRHR1 |
P34998 |
B | 1 Reference(s) |
| T56NC7 | Beta-defensin 4A | DEFB4A; DEFB4B |
O15263 |
B | 1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
B | 1 Reference(s) |
| T07NML | P-selectin | SELP |
P16109 |
B | 1 Reference(s) |
| T14FV1 | Cadherin-5 | CDH5 |
P33151 |
B | 1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
B | 1 Reference(s) |
| T06N1B | Histamine H1 receptor | HRH1 |
P35367 |
B | 2 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 7)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0244 | Mi La | 蜜蜡 | Bee wax | Apis cerana |
| H0713 | Che Qian Cao | 车前草 | all-grass of rippleseed plantain | Plantago depressa |
| H0133 | Li Yu | 鲤鱼 | Carp | Cyprinus carpio |
| H1040 | Feng Mi | 蜂蜜 | Honey | Apis cerana |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0006 | Bai Qu Cai | 白屈菜 | Greater celandine | Chelidonium majus |
Ckey description of the interaction between compound and target