Target Description

Type Detail
Target ID T06N1B
Protein Name Histamine H1 receptor
Uniprot ID P35367
Protein Name Alias H1R;  HH1R
Gene ID 3269
Gene Symbol HRH1
Gene Alias NA
TTD T77913: Successful target
Pfam PF00001
GO
0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

0030425:dendrite

0007268:chemical synaptic transmission

0007186:G protein-coupled receptor signaling pathway

0005829:cytosol

0004969:histamine receptor activity

0004993:G protein-coupled serotonin receptor activity

0045202:synapse

0048016:inositol phosphate-mediated signaling

0005886:plasma membrane

0004930:G protein-coupled receptor activity

0030594:neurotransmitter receptor activity

0005887:integral component of plasma membrane

0032962:positive regulation of inositol trisphosphate biosynthetic process

0045907:positive regulation of vasoconstriction

0048167:regulation of synaptic plasticity

0048245:eosinophil chemotaxis

0007613:memory

0071420:cellular response to histamine

0043114:regulation of vascular permeability

0007200:phospholipase C-activating G protein-coupled receptor signaling pathway

0006954:inflammatory response

0008542:visual learning

PDB 3RZE
Drugbank DB00656 ; DB00734 ; DB00768 ; DB00283 ; DB04837 ; DB04890 ; DB00502 ; DB00458 ; DB00719 ; DB00902 ; DB00767 ; DB00408 ; DB00555 ; DB00972 ; DB00354 ; DB00321 ; DB00748 ; DB09555 ; DB00920 ; DB01114 ; DB00777 ; DB05080 ; DB11591 ; DB01071 ; DB00215 ; DB00934 ; DB01069 ; DB09167 ; DB00433 ; DB06766 ; DB01239 ; DB11235 ; DB01237 ; DB08801 ; DB00246 ; DB00751 ; DB08799 ; DB00950 ; DB08936 ; DB01246 ; DB08922 ; DB01267 ; DB04841 ; DB00341 ; DB06691 ; DB06148 ; DB05492 ; DB06153 ; DB00835 ; DB11614 ; DB00420 ; DB00543 ; DB00737 ; DB01615 ; DB00363 ; DB04946 ; DB01146 ; DB05079 ; DB01173 ; DB01176 ; DB06216 ; DB01084 ; DB00568 ; DB00540 ; DB01106 ; DB05345 ; DB06698 ; DB00967 ; DB01619 ; DB01403 ; DB00715 ; DB09488 ; DB00245 ; DB00434 ; DB00405 ; DB00637 ; DB01238 ; DB09195 ; DB00557 ; DB06229 ; DB04905 ; DB01175 ; DB00985 ; DB01620 ; DB09016 ; DB00366 ; DB00477 ; DB01624 ; DB00427 ; DB06678 ; DB01151 ; DB01075 ; DB01142 ; DB14185 ; DB06282 ; DB00726 ; DB00792 ; DB06016 ; DB00370 ; DB00334 ; DB01224 ; DB05381 ; DB00797 ; DB08802 ; DB00455 ; DB08800 ; DB00342
KEGG hsa:3269

Related Compounds  (Total: 6)

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C0028
Name: Diphenhydramine
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C0125
Name: Histamine
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C0197
Name: Loratadine
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C0734
Name: Histamine
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C1027
Name: kainic acid


Related Herbs  (Total: 11)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0313 Pu Er Min扑尔敏 Chlorpheniramine maleateChlorpheniramini maleas
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H1040 Feng Mi蜂蜜 HoneyApis cerana
H0713 Che Qian Cao车前草 all-grass of rippleseed plantainPlantago depressa
H0244 Mi La蜜蜡 Bee waxApis cerana
H1208 Hu Ma Ren胡麻仁 white seed of oriental sesameSesamum indicum
H0133 Li Yu鲤鱼 CarpCyprinus carpio
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1181 Hei Zhi Ma黑芝麻 Oriental sesameSesamum indicum
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1207 Hu Ma胡麻 white seed of oriental sesameSesamum indicum