HIT-result

Type	Detail
Target ID	T14FV1
Protein Name	Cadherin-5
Uniprot ID	P33151
Protein Name Alias	7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD antigen CD144
Gene ID	1003
Gene Symbol	CDH5
Gene Alias	NA
TTD	T68009: Research target
Pfam	PF00028 ; PF01049
GO	0001932:regulation of protein phosphorylation 0001944:vasculature development 0005923:bicellular tight junction 0008013:beta-catenin binding 2000352:negative regulation of endothelial cell apoptotic process 0009986:cell surface 0016021:integral component of membrane 0044331:cell-cell adhesion mediated by cadherin 0019903:protein phosphatase binding 1990782:protein tyrosine kinase binding 1903142:positive regulation of establishment of endothelial barrier 0016020:membrane 0043534:blood vessel endothelial cell migration 0007156:homophilic cell adhesion via plasma membrane adhesion molecules 0005102:signaling receptor binding 0007043:cell-cell junction assembly 0007275:multicellular organism development 0030054:cell junction 0034332:adherens junction organization 0070700:BMP receptor binding 0035307:positive regulation of protein dephosphorylation 0009897:external side of plasma membrane 2000114:regulation of establishment of cell polarity 0070051:fibrinogen binding 0005886:plasma membrane 0005911:cell-cell junction 0098742:cell-cell adhesion via plasma-membrane adhesion molecules 0031965:nuclear membrane 0005654:nucleoplasm 0044325:ion channel binding 0031115:negative regulation of microtubule polymerization 0001955:blood vessel maturation 1902396:protein localization to bicellular tight junction 0030513:positive regulation of BMP signaling pathway 0043184:vascular endothelial growth factor receptor 2 binding 0030335:positive regulation of cell migration 0098609:cell-cell adhesion 0070830:bicellular tight junction assembly 0050728:negative regulation of inflammatory response 0045766:positive regulation of angiogenesis 0035633:maintenance of blood-brain barrier 0031334:positive regulation of protein-containing complex assembly 0006874:cellular calcium ion homeostasis 0005509:calcium ion binding 0043114:regulation of vascular permeability 0007179:transforming growth factor beta receptor signaling pathway 0010628:positive regulation of gene expression 0045296:cadherin binding 0000902:cell morphogenesis 0016339:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 0008285:negative regulation of cell population proliferation 0005912:adherens junction 0016342:catenin complex
PDB	NA
Drugbank	DB05685 ; DB00480
KEGG	hsa:1003

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Name: Histamine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0133	Li Yu	鲤鱼	Carp	Cyprinus carpio
H0713	Che Qian Cao	车前草	all-grass of rippleseed plantain	Plantago depressa
H1040	Feng Mi	蜂蜜	Honey	Apis cerana
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H0244	Mi La	蜜蜡	Bee wax	Apis cerana
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens