HIT-result

Target Description

Type	Detail
Target ID	T60WNX
Protein Name	Vasopressin-neurophysin 2-copeptin
Uniprot ID	P01185
Protein Name Alias	AVP-NPII
Gene ID	551
Gene Symbol	AVP
Gene Alias	ARVP; VP
TTD	T20975: Research target
Pfam	PF00184 ; PF00220
GO	0035813:regulation of renal sodium excretion 0033574:response to testosterone 0005184:neuropeptide hormone activity 0031394:positive regulation of prostaglandin biosynthetic process 0030425:dendrite 0004672:protein kinase activity 0043084:penile erection 0005829:cytosol 0007621:negative regulation of female receptivity 0014049:positive regulation of glutamate secretion 0051970:negative regulation of transmission of nerve impulse 0007204:positive regulation of cytosolic calcium ion concentration 0035176:social behavior 0032849:positive regulation of cellular pH reduction 0007626:locomotory behavior 0008284:positive regulation of cell population proliferation 0003084:positive regulation of systemic arterial blood pressure 0045907:positive regulation of vasoconstriction 0061024:membrane organization 0090201:negative regulation of release of cytochrome c from mitochondria 0031895:V1B vasopressin receptor binding 0003091:renal water homeostasis 0005615:extracellular space 0070528:protein kinase C signaling 0002125:maternal aggressive behavior 0042310:vasoconstriction 0006091:generation of precursor metabolites and energy 0010628:positive regulation of gene expression 0002862:negative regulation of inflammatory response to antigenic stimulus 0030141:secretory granule 0005185:neurohypophyseal hormone activity 0042538:hyperosmotic salinity response 0031894:V1A vasopressin receptor binding 0070371:ERK1 and ERK2 cascade 0030669:clathrin-coated endocytic vesicle membrane 0007267:cell-cell signaling 0035094:response to nicotine 0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0042711:maternal behavior 0005576:extracellular region 0005102:signaling receptor binding 0030307:positive regulation of cell growth 0045471:response to ethanol 0007625:grooming behavior 0007165:signal transduction 0007186:G protein-coupled receptor signaling pathway 0006833:water transport 0043027:cysteine-type endopeptidase inhibitor activity involved in apoptotic process 0033138:positive regulation of peptidyl-serine phosphorylation 0043066:negative regulation of apoptotic process
PDB	NA
Drugbank	NA
KEGG	hsa:551

Type

Detail

Target ID

T60WNX

Protein Name

Vasopressin-neurophysin 2-copeptin

Uniprot ID

P01185

Protein Name Alias

AVP-NPII

Gene ID

551

Gene Symbol

AVP

Gene Alias

ARVP; VP

TTD

T20975: Research target

Pfam

PF00184 ; PF00220

0035813:regulation of renal sodium excretion

0033574:response to testosterone

0005184:neuropeptide hormone activity

0031394:positive regulation of prostaglandin biosynthetic process

0030425:dendrite

0004672:protein kinase activity

0043084:penile erection

0005829:cytosol

0007621:negative regulation of female receptivity

0014049:positive regulation of glutamate secretion

0051970:negative regulation of transmission of nerve impulse

0007204:positive regulation of cytosolic calcium ion concentration

0035176:social behavior

0032849:positive regulation of cellular pH reduction

0007626:locomotory behavior

0008284:positive regulation of cell population proliferation

0003084:positive regulation of systemic arterial blood pressure

0045907:positive regulation of vasoconstriction

0061024:membrane organization

0090201:negative regulation of release of cytochrome c from mitochondria

0031895:V1B vasopressin receptor binding

0003091:renal water homeostasis

0005615:extracellular space

0070528:protein kinase C signaling

0002125:maternal aggressive behavior

0042310:vasoconstriction

0006091:generation of precursor metabolites and energy

0010628:positive regulation of gene expression

0002862:negative regulation of inflammatory response to antigenic stimulus

0030141:secretory granule

0005185:neurohypophyseal hormone activity

0042538:hyperosmotic salinity response

0031894:V1A vasopressin receptor binding

0070371:ERK1 and ERK2 cascade

0030669:clathrin-coated endocytic vesicle membrane

0007267:cell-cell signaling

0035094:response to nicotine

0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0042711:maternal behavior

0005576:extracellular region

0005102:signaling receptor binding

0030307:positive regulation of cell growth

0045471:response to ethanol

0007625:grooming behavior

0007165:signal transduction

0007186:G protein-coupled receptor signaling pathway

0006833:water transport

0043027:cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0033138:positive regulation of peptidyl-serine phosphorylation

0043066:negative regulation of apoptotic process

PDB

Drugbank

KEGG

hsa:551

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0077	Jiu	酒	Ethanol	Vinum
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 18)