HIT-result

Type	Detail
Target ID	T88E8M
Protein Name	Carbonic anhydrase 9
Uniprot ID	Q16790
Protein Name Alias	EC 4.2.1.1; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1
Gene ID	768
Gene Symbol	CA9
Gene Alias	G250; MN
TTD	T64567: Clinical Trial target
Pfam	PF00194
GO	0004089:carbonate dehydratase activity 0002009:morphogenesis of an epithelium 0031528:microvillus membrane 0016323:basolateral plasma membrane 0015701:bicarbonate transport 0006730:one-carbon metabolic process 0016021:integral component of membrane 0042493:response to drug 0061418:regulation of transcription from RNA polymerase II promoter in response to hypoxia 0008270:zinc ion binding 0033574:response to testosterone 0005730:nucleolus 0016836:hydro-lyase activity 0046903:secretion 0005886:plasma membrane
PDB	6FE2 ; 6G98 ; 6G9U ; 6FE0 ; 6TL5 ; 5FL4 ; 5FL5 ; 6QN5 ; 5FL6 ; 6RQW ; 6QUT ; 3IAI ; 6FE1 ; 6Y74 ; 5DVX ; 6QN6 ; 2HKF ; 6QN2 ; 6RQN ; 6RQQ ; 6TL6 ; 6RQU
Drugbank	DB00909 ; DB00606 ; DB09460 ; DB00562 ; DB00774 ; DB05304 ; DB08846
KEGG	hsa:768

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1163	He Bao Cao	荷包草	NA	Lamprocapnos spectabilis
H0582	Cao Dou Kou Ren	草豆蔻仁	Katsumada galangal	Alpinia katsumadai
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H0574	Cao Dou Kou	草豆蔻	Katsumada galangal	Alpinia katsumadai
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H1214	Hua Jiao	花椒	Bunge pricklyash	Zanthoxylum bungeanum
H0233	Mao Liang Mian Zhen	毛两面针	NA	Zanthoxylum nitidum

Target Description