Compound Description

ID:   C1226 Common name:   Chalcone
IUPAC:  (E)-1,3-diphenylprop-2-en-1-one CAS:  CAS:94-41-7
Chembl ID:   CHEMBL7976 Pubchem ID:   CID:637760
Formula:  C15H12O TCM-ID:  TCMC889
Smiles:  O=C(c1ccccc1)/C=C/c1ccccc1
Alias:

Chalcone;

1,3-Diphenyl-2-propen-1-one;

1,3-Diphenyl-1-propen-3-one;

1,3-Diphenyl-2-propenone;

1,3-Diphenyl-3-oxo-1-propene;

1,3-Diphenylpropen-3-one;

1,3-Diphenylpropenone;

1-Benzoyl-2-phenylethene;

1-Benzoyl-2-phenylethylene;

1-Phenyl-2-benzoylethylene;

2-Benzalacetophenone;

2-Benzylideneacetophenone;

3-Phenylacrylophenone;

BAP;

Benzalacetophenone;

Benzylideneacetophenone;

Benzylidenecetophenone;

Chalkone;

Cinnamophenone;

NSC 26612;

NSC 4523;

Phenyl 2-phenylethenyl ketone;

Phenyl 2-phenylvinyl ketone;

Phenyl styryl ketone;

Styryl phenyl ketone;

α-Benzylideneacetophenone;

β-Benzoylstyrene;

β-Phenylacrylophenone;

ω-Benzylideneacetophenone
Structure:

Related Targets  (Total: 12)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T84W8G Aryl hydrocarbon receptorAHR P35869
A 2 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
A 1 Reference(s)
T63BQU Cytochrome P450 1A1CYP1A1 P04798
A 3 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
A 1 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
A 1 Reference(s)
T88E8M Carbonic anhydrase 9CA9 Q16790
A 1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
A 1 Reference(s)
T15ZAV Lymphocyte antigen 96LY96 Q9Y6Y9
B 2 Reference(s)
T04IGS Caseinolytic peptidase B protein homologCLPB Q9H078
B 1 Reference(s)
T88IXL Histone H2AXH2AX P16104
B 1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
C 1 Reference(s)
T82JWE Cellular tumor antigen p53TP53 P04637
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai