HIT-result

Type	Detail
Target ID	T88IXL
Protein Name	Histone H2AX
Uniprot ID	P16104
Protein Name Alias	H2a/x; Histone H2A.X
Gene ID	3014
Gene Symbol	H2AX
Gene Alias	H2AFX
TTD	T55244: Research target
Pfam	PF16211 ; PF00125
GO	0003677:DNA binding 0005634:nucleus 0071480:cellular response to gamma radiation 0070062:extracellular exosome 0006302:double-strand break repair 0000794:condensed nuclear chromosome 0006334:nucleosome assembly 0005813:centrosome 0010212:response to ionizing radiation 0000786:nucleosome 0021987:cerebral cortex development 0001741:XY body 0007283:spermatogenesis 0000724:double-strand break repair via homologous recombination 0003684:damaged DNA binding 0019899:enzyme binding 0051321:meiotic cell cycle 0090398:cellular senescence 0001673:male germ cell nucleus 0006303:double-strand break repair via nonhomologous end joining 0005657:replication fork 0042393:histone binding 0016032:viral process 0090734:site of DNA damage 0046982:protein heterodimerization activity 0005654:nucleoplasm 0035861:site of double-strand break 0016607:nuclear speck 0000077:DNA damage checkpoint 0045739:positive regulation of DNA repair 0006342:chromatin silencing 0006974:cellular response to DNA damage stimulus
PDB	6K1J ; 6K1K ; 2D31 ; 3SHV ; 3SZM ; 1YDP ; 3U3Z ; 2AZM ; 6K1I ; 2DYP ; 3SQD
Drugbank	NA
KEGG	hsa:3014

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0574	Cao Dou Kou	草豆蔻	Katsumada galangal	Alpinia katsumadai
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H0405	Shan Dou Gen	山豆根	Tonkin sophora root	Sophora subprostrata
H0111	Ku Shen	苦参	Lightyellow sophora	Sophora flavescens
H0582	Cao Dou Kou Ren	草豆蔻仁	Katsumada galangal	Alpinia katsumadai

Target Description