Target Description

Type Detail
Target ID T88IXL
Protein Name Histone H2AX
Uniprot ID P16104
Protein Name Alias H2a/x;  Histone H2A.X
Gene ID 3014
Gene Symbol H2AX
Gene Alias H2AFX
TTD T55244: Research target
Pfam PF16211 ; PF00125
0003677:DNA binding


0071480:cellular response to gamma radiation

0070062:extracellular exosome

0006302:double-strand break repair

0000794:condensed nuclear chromosome

0006334:nucleosome assembly


0010212:response to ionizing radiation


0021987:cerebral cortex development

0001741:XY body


0000724:double-strand break repair via homologous recombination

0003684:damaged DNA binding

0019899:enzyme binding

0051321:meiotic cell cycle

0090398:cellular senescence

0001673:male germ cell nucleus

0006303:double-strand break repair via nonhomologous end joining

0005657:replication fork

0042393:histone binding

0016032:viral process

0090734:site of DNA damage

0046982:protein heterodimerization activity


0035861:site of double-strand break

0016607:nuclear speck

0000077:DNA damage checkpoint

0045739:positive regulation of DNA repair

0006342:chromatin silencing

0006974:cellular response to DNA damage stimulus

PDB 6K1J ; 6K1K ; 2D31 ; 3SHV ; 3SZM ; 1YDP ; 3U3Z ; 2AZM ; 6K1I ; 2DYP ; 3SQD
Drugbank NA
KEGG hsa:3014

Related Compounds  (Total: 2)

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Name: Oxymatrine
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Name: Chalcone

Related Herbs  (Total: 5)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H0405 Shan Dou Gen山豆根 Tonkin sophora rootSophora subprostrata
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai