Target Description

Type Detail
Target ID T00W4R
Protein Name B1 bradykinin receptor
Uniprot ID P46663
Protein Name Alias B1R;  BK-1 receptor
Gene ID 623
Gene Symbol BDKRB1
Gene Alias BRADYB1
TTD T58589: Clinical Trial target
Pfam PF00001
GO
0045776:negative regulation of blood pressure

0005783:endoplasmic reticulum

0007204:positive regulation of cytosolic calcium ion concentration

0009612:response to mechanical stimulus

0004947:bradykinin receptor activity

0051281:positive regulation of release of sequestered calcium ion into cytosol

0007205:protein kinase C-activating G protein-coupled receptor signaling pathway

0043005:neuron projection

0005887:integral component of plasma membrane

0042277:peptide binding

0005886:plasma membrane

0002687:positive regulation of leukocyte migration

0001933:negative regulation of protein phosphorylation

0030308:negative regulation of cell growth

0004930:G protein-coupled receptor activity

0006954:inflammatory response

0007186:G protein-coupled receptor signaling pathway

0016477:cell migration

0032496:response to lipopolysaccharide

0019233:sensory perception of pain

PDB NA
Drugbank DB09477 ; DB01593 ; DB01197 ; DB14533 ; DB14487 ; DB00178 ; DB14548
KEGG hsa:623

Related Compounds  (Total: 1)

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C0734
Name: Histamine


Related Herbs  (Total: 1)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus