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Target Description
Type
Detail
Target ID
T76F14
Protein Name
DNA mismatch repair protein Msh2
Uniprot ID
P43246
Protein Name Alias
hMSH2; MutS protein homolog 2
Gene ID
4436
Gene Symbol
MSH2
Gene Alias
NA
TTD
T46849: Research target
Pfam
PF05190
;
PF05188
;
PF00488
;
PF05192
;
PF01624
GO
0032137:guanine/thymine mispair binding
0031573:intra-S DNA damage checkpoint
0048304:positive regulation of isotype switching to IgG isotypes
0003684:damaged DNA binding
0019724:B cell mediated immunity
0002204:somatic recombination of immunoglobulin genes involved in immune response
0005524:ATP binding
0016446:somatic hypermutation of immunoglobulin genes
0051096:positive regulation of helicase activity
0016020:membrane
0008022:protein C-terminus binding
0003682:chromatin binding
0006119:oxidative phosphorylation
0000781:chromosome, telomeric region
0006298:mismatch repair
0007050:cell cycle arrest
0008094:DNA-dependent ATPase activity
0045910:negative regulation of DNA recombination
0007281:germ cell development
0019237:centromeric DNA binding
0008340:determination of adult lifespan
0005654:nucleoplasm
0001701:in utero embryonic development
0019899:enzyme binding
0006301:postreplication repair
0071168:protein localization to chromatin
0003677:DNA binding
0043570:maintenance of DNA repeat elements
0048298:positive regulation of isotype switching to IgA isotypes
0042803:protein homodimerization activity
0006302:double-strand break repair
0005634:nucleus
0019901:protein kinase binding
0032301:MutSalpha complex
0006281:DNA repair
0000406:double-strand/single-strand DNA junction binding
0008584:male gonad development
0043524:negative regulation of neuron apoptotic process
0030183:B cell differentiation
0032302:MutSbeta complex
0045190:isotype switching
0010165:response to X-ray
0016447:somatic recombination of immunoglobulin gene segments
0042771:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0032300:mismatch repair complex
0006310:DNA recombination
0010224:response to UV-B
PDB
2O8B
;
2O8F
;
2O8C
;
3THZ
;
3THX
;
2O8E
;
3THW
;
3THY
;
2O8D
Drugbank
NA
KEGG
hsa:4436
Related Compounds (Total: 1)
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C1227
Name: Chelerythrine
Related Herbs (Total: 4)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0006
Bai Qu Cai
白屈菜
Greater celandine
Chelidonium majus
H1163
He Bao Cao
荷包草
NA
Lamprocapnos spectabilis
H1214
Hua Jiao
花椒
Bunge pricklyash
Zanthoxylum bungeanum
H0233
Mao Liang Mian Zhen
毛两面针
NA
Zanthoxylum nitidum