HIT-result

Type	Detail
Target ID	T01L5I
Protein Name	DNA mismatch repair protein Msh6
Uniprot ID	P52701
Protein Name Alias	hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS protein homolog 6; MutS-alpha 160 kDa subunit; p160
Gene ID	2956
Gene Symbol	MSH6
Gene Alias	GTBP
TTD	NA
Pfam	PF05190 ; PF00855 ; PF05188 ; PF00488 ; PF05192 ; PF01624
GO	0032137:guanine/thymine mispair binding 0006290:pyrimidine dimer repair 0003684:damaged DNA binding 0005524:ATP binding 0016446:somatic hypermutation of immunoglobulin genes 0051096:positive regulation of helicase activity 0035064:methylated histone binding 0008630:intrinsic apoptotic signaling pathway in response to DNA damage 0003682:chromatin binding 0006298:mismatch repair 0097193:intrinsic apoptotic signaling pathway 0005829:cytosol 0008094:DNA-dependent ATPase activity 0045910:negative regulation of DNA recombination 0005794:Golgi apparatus 0009411:response to UV 0008340:determination of adult lifespan 0000710:meiotic mismatch repair 0005654:nucleoplasm 0019899:enzyme binding 0036297:interstrand cross-link repair 0000785:chromatin 0005634:nucleus 0032301:MutSalpha complex 0006281:DNA repair 0016447:somatic recombination of immunoglobulin gene segments 0043231:intracellular membrane-bounded organelle 0016032:viral process 0032300:mismatch repair complex 0045190:isotype switching 0030983:mismatched DNA binding
PDB	2O8B ; 2GFU ; 2O8F ; 2O8C ; 6OQM ; 2O8E ; 2O8D
Drugbank	NA
KEGG	hsa:2956

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1214	Hua Jiao	花椒	Bunge pricklyash	Zanthoxylum bungeanum
H0233	Mao Liang Mian Zhen	毛两面针	NA	Zanthoxylum nitidum
H1163	He Bao Cao	荷包草	NA	Lamprocapnos spectabilis
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus

Target Description