Target Description

Type Detail
Target ID T29C6N
Protein Name Ezrin
Uniprot ID P15311
Protein Name Alias Cytovillin;  Villin-2;  p81
Gene ID 7430
Gene Symbol EZR
Gene Alias VIL2
TTD T96256: Research target
Pfam PF00769 ; PF00373 ; PF09379 ; PF09380
GO
0003779:actin binding

0061028:establishment of endothelial barrier

0019904:protein domain specific binding

0051286:cell tip

0001726:ruffle

0051017:actin filament bundle assembly

0032532:regulation of microvillus length

0046847:filopodium assembly

0034236:protein kinase A catalytic subunit binding

0050860:negative regulation of T cell receptor signaling pathway

0043622:cortical microtubule organization

0044853:plasma membrane raft

0051015:actin filament binding

0036064:ciliary basal body

0070373:negative regulation of ERK1 and ERK2 cascade

0040018:positive regulation of multicellular organism growth

0097449:astrocyte projection

0042802:identical protein binding

0051117:ATPase binding

0034237:protein kinase A regulatory subunit binding

0022614:membrane to membrane docking

0097718:disordered domain specific binding

0005829:cytosol

0050839:cell adhesion molecule binding

0048015:phosphatidylinositol-mediated signaling

0097454:Schwann cell microvillus

0016324:apical plasma membrane

2000643:positive regulation of early endosome to late endosome transport

0001951:intestinal D-glucose absorption

0001931:uropod

0005737:cytoplasm

0030175:filopodium

0005615:extracellular space

0010628:positive regulation of gene expression

1902966:positive regulation of protein localization to early endosome

0048471:perinuclear region of cytoplasm

0001650:fibrillar center

0030953:astral microtubule organization

0008360:regulation of cell shape

0019898:extrinsic component of membrane

0032587:ruffle membrane

0098592:cytoplasmic side of apical plasma membrane

0045177:apical part of cell

0030033:microvillus assembly

1903078:positive regulation of protein localization to plasma membrane

0005768:endosome

0050714:positive regulation of protein secretion

0044393:microspike

0044548:S100 protein binding

0003376:sphingosine-1-phosphate receptor signaling pathway

0010737:protein kinase A signaling

0031623:receptor internalization

0005884:actin filament

0071320:cellular response to cAMP

0005903:brush border

0016020:membrane

0003723:RNA binding

0031528:microvillus membrane

0072659:protein localization to plasma membrane

1903364:positive regulation of cellular protein catabolic process

0000122:negative regulation of transcription by RNA polymerase II

0031532:actin cytoskeleton reorganization

0034629:cellular protein-containing complex localization

0035088:establishment or maintenance of apical/basal cell polarity

0015629:actin cytoskeleton

0001772:immunological synapse

0005902:microvillus

0070062:extracellular exosome

1903753:negative regulation of p38MAPK cascade

0005925:focal adhesion

0030863:cortical cytoskeleton

1902115:regulation of organelle assembly

0051018:protein kinase A binding

0072697:protein localization to cell cortex

1902896:terminal web assembly

0071944:cell periphery

0008017:microtubule binding

0044297:cell body

0005886:plasma membrane

0031982:vesicle

0051660:establishment of centrosome localization

0032991:protein-containing complex

0007159:leukocyte cell-cell adhesion

0032703:negative regulation of interleukin-2 production

0008022:protein C-terminus binding

0042995:cell projection

0045296:cadherin binding

0016323:basolateral plasma membrane

0007411:axon guidance

0030315:T-tubule

PDB 4RM8 ; 4RM9 ; 1NI2 ; 4RMA
Drugbank NA
KEGG hsa:7430

Related Compounds  (Total: 1)

Go to browser
C1171
Name: Berberine


Related Herbs  (Total: 24)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1242 Huang Lian Gan Jin Gao黄连干浸膏 Coptis deltoideaCoptis chinensis
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H1061 Bai He百合 LilyLilium brownii
H0006 Bai Qu Cai白屈菜 Greater celandineChelidonium majus
H0706 Yan Hu Suo延胡索 YanhusuoCorydalis yanhusuo
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H0651 Xiang Yuan香橼 Wilson citronCitrus medica
H0029 Jiang Huang Lian姜黄连 Coptis deltoideaCoptis chinensis
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H0827 Zhu Hong Jun竹红菌 Bambusa hypocrella*Hypocrella bambusae
H0760 Yu Huang Lian萸黄连 Coptis deltoideaCoptis chinensis
H0682 Xiong Huang Lian雄黄连 Coptis deltoideaCoptis chinensis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0785 Ze Xi Huang Lian择细黄连 Coptis deltoideaCoptis chinensis
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H0872 Chuan Huang Lian川黄连 rhizome of chinese goldthreadCoptis chinensis
H1068 Bai He Liu Jin Gao百合流浸膏 LilyLilium brownii
H1243 Huang Lian Xu黄连须 Coptis deltoideaCoptis chinensis
H0652 Xiang Yuan Pi香橼皮 Wilson citronCitrus medica
H1241 Huang Lian黄连 Coptis deltoideaCoptis chinensis
H0633 Xia Tian Wu夏天无 Decumbent corydalisCorydalis decumbens
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense
H0082 Jiu Huang Lian酒黄连 Coptis deltoideaCoptis chinensis