Compound Description

ID:   C0255 Common name:   Norepinephrine
IUPAC:  4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol CAS:  CAS:51-41-2
Chembl ID:   CHEMBL1437 Pubchem ID:   CID:439260
Formula:  C8H11NO3 TCM-ID:  TCMC1758
Smiles:  C1=CC(=C(C=C1C(CN)O)O)O
Alias:

1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-;

Arterenol, l-;

Benzyl alcohol, α-(aminomethyl)-3,4-dihydroxy-, (-)-;

4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol;

(-)-Arterenol;

(-)-Noradrenaline;

(-)-Norepinephrine;

(-)-α-(Aminomethyl)protocatechuyl alcohol;

(R)-(-)-Norepinephrine;

(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol;

(R)-Noradrenaline;

(R)-Norepinephrine;

Adrenor;

Aktamin;

Arterenol;

L-Noradrenaline;

Levarterenol;

Levoarterenol;

Levonor;

Levonoradrenaline;

Levonorepinephrine;

Levophed;

Nor-Epirenan;

Noradrenalin;

Noradrenaline;

Norartrinal;

Norepinephrine;

Norepirenamine;

Sympathin E;

l-1-(3,4-Dihydroxyphenyl)-2-aminoethanol;

l-2-Amino-1-(3,4-dihydroxyphenyl)ethanol;

l-3,4-Dihydroxyphenylethanolamine;

l-Arterenol;

l-Noradrenaline;

l-Norepinephrine;

l-α-(Aminomethyl)-3,4-dihydroxybenzyl alcohol
Structure:

Related Targets  (Total: 32)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T23VMI Tumor necrosis factorTNF P01375
A 1 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
A 1 Reference(s)
T11R4S Tumor necrosis factor receptor superfamily member 5CD40 P25942
A 1 Reference(s)
T92UWJ Beta-2 adrenergic receptorADRB2 P07550
A 1 Reference(s)
T01QLH Estrogen receptorESR1 P03372
A 1 Reference(s)
T09HVO Sodium/hydrogen exchanger 3SLC9A3 P48764
B 1 Reference(s)
T30NJL Electrogenic sodium bicarbonate cotransporter 1SLC4A4 Q9Y6R1
B 1 Reference(s)
T44MAF Aquaporin-2AQP2 P41181
B 1 Reference(s)
T12T4H Brain-derived neurotrophic factorBDNF P23560
B 1 Reference(s)
T23TJV Tyrosine 3-monooxygenaseTH P07101
B 1 Reference(s)
T14YKW Monocarboxylate transporter 2SLC16A7 O60669
B 2 Reference(s)
T76B0A Gap junction alpha-1 proteinGJA1 P17302
B 1 Reference(s)
T21DZX Amine oxidase [flavin-containing] AMAOA P21397
B 1 Reference(s)
T35XJB Period circadian protein homolog 1PER1 O15534
B 1 Reference(s)
T84FRS Oxytocin-neurophysin 1OXT P01178
B 1 Reference(s)
T63GUB Proto-oncogene c-FosFOS P01100
B 1 Reference(s)
T58J2Y Peroxisome proliferator-activated receptor gammaPPARG P37231
B 1 Reference(s)
T08U92 Mitochondrial brown fat uncoupling protein 1UCP1 P25874
C 1 Reference(s)
T52UTG HaptoglobinHP P00738
C 1 Reference(s)
T67RBZ Mitochondrial uncoupling protein 2UCP2 P55851
C 1 Reference(s)
T28HOM LeptinLEP P41159
C 1 Reference(s)
T93VFT Endothelin-1EDN1 P05305
C 1 Reference(s)
T71TWH cAMP-responsive element modulatorCREM Q03060
C 1 Reference(s)
T48DQY Sodium/glucose cotransporter 2SLC5A2 P31639
C 1 Reference(s)
T20TB8 NADPH oxidase 1NOX1 Q9Y5S8
C 1 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
C 1 Reference(s)
T88QQE Fibroblast growth factor 2FGF2 P09038
C 1 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
C 1 Reference(s)
T86YQL ProlactinPRL P01236
C 1 Reference(s)
T03CZ8 Catechol O-methyltransferaseCOMT P21964
C 1 Reference(s)
T69T7P Dopamine beta-hydroxylaseDBH P09172
C 1 Reference(s)
T33OPP Interleukin-6IL6 P05231
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 13)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0488 Shui Niu Jiao Gan Jin Gao水牛角干浸膏 Buffalo hornBubalus bubalis
H0732 Ye Mu Dan野牡丹 Common melastomaMelastoma candidum
H0489 Shui Niu Jiao Nong Suo Fen水牛角浓缩粉 Buffalo hornBubalus bubalis
H0487 Shui Niu Jiao水牛角 Buffalo hornBubalus bubalis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0643 Xiang Jiao橡胶 RubberMusa paradisiaca var. sapientum
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0293 Niu Jiao Tan牛角炭 Buffalo hornBubalus bubalis
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0292 Niu Jiao Jian Fen牛角尖粉 Buffalo hornBubalus bubalis
H0291 Niu Jiao Fen牛角粉 Buffalo hornBubalus bubalis
H0214 Bei He Huan北合欢 AlbiziaAlbizia julibrissin