Target Description

Type Detail
Target ID T89SY7
Protein Name Zinc finger and BTB domain-containing protein 16
Uniprot ID Q05516
Protein Name Alias Promyelocytic leukemia zinc finger protein;  Zinc finger protein 145;  Zinc finger protein PLZF
Gene ID 7704
Gene Symbol ZBTB16
Gene Alias PLZF;  ZNF145
TTD NA
Pfam PF00096 ; PF00651
GO
0003677:DNA binding

0042802:identical protein binding

0005634:nucleus

0016567:protein ubiquitination

0034504:protein localization to nucleus

0061036:positive regulation of cartilage development

0019904:protein domain specific binding

0051138:positive regulation of NK T cell differentiation

0006915:apoptotic process

0042733:embryonic digit morphogenesis

0008285:negative regulation of cell population proliferation

0045892:negative regulation of transcription, DNA-templated

0017053:transcription repressor complex

0016605:PML body

0051216:cartilage development

0045600:positive regulation of fat cell differentiation

0032332:positive regulation of chondrocyte differentiation

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0005829:cytosol

0045778:positive regulation of ossification

0005886:plasma membrane

0048133:male germ-line stem cell asymmetric division

0009880:embryonic pattern specification

0030099:myeloid cell differentiation

0035116:embryonic hindlimb morphogenesis

0035136:forelimb morphogenesis

0009952:anterior/posterior pattern specification

0001823:mesonephros development

0045638:negative regulation of myeloid cell differentiation

0007417:central nervous system development

0030097:hemopoiesis

0032991:protein-containing complex

0016604:nuclear body

0043065:positive regulation of apoptotic process

0045893:positive regulation of transcription, DNA-templated

0000122:negative regulation of transcription by RNA polymerase II

0042803:protein homodimerization activity

0006357:regulation of transcription by RNA polymerase II

0008022:protein C-terminus binding

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

0046872:metal ion binding

0016607:nuclear speck

0043687:post-translational protein modification

PDB 1CS3 ; 1BUO
Drugbank NA
KEGG hsa:7704

Related Compounds  (Total: 1)

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C0101
Name: Genistein


Related Herbs  (Total: 45)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1227 Huai Zhi槐枝 NASophora japonica
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H0852 Zi Tan紫檀 Burmacoast padaukPterocarpus indicus
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H0980 Di Yu Tan地榆炭 Garden burnetSanguisorba officinalis
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0026 Jiang Soybean pasteGlycine max
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0575 Tu Ku Shen土苦参 all-grass of hooker wingheadSophora flavescens
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0129 Le Xian Cai勒苋菜 NAAmaranthus spinosus
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0979 Di Yu地榆 Garden burnetSanguisorba officinalis
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0792 Zhang Yu章鱼 Common atlantic octopusOctopus vulgaris
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0906 Ci Wan刺苋 spiny amaranthAmaranthus spinosus
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H1224 Huai Jiao槐角 pod of japanese pagodatreeSophora japonica
H1222 Huai Hua槐花 flower bud of japanese pagodatreeSophora japonica
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0533 Teng Ku Shen藤苦参 NASophora flavescens
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1225 Huai Mi槐米 NASophora japonica
H1007 Dou You豆油 Soybean oilGlycine max
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis