HIT-result

Target Description

Type	Detail
Target ID	T53G91
Protein Name	Nischarin
Uniprot ID	Q9Y2I1
Protein Name Alias	Imidazoline receptor 1; I-1; IR1; Imidazoline receptor antisera-selected protein; hIRAS; Imidazoline-1 receptor; I1R; Imidazoline-1 receptor candidate protein; I-1 receptor candidate protein; I1R candidate protein
Gene ID	11188
Gene Symbol	NISCH
Gene Alias	IRAS; KIAA0975
TTD	T78943: Research target
Pfam	PF00787
GO	0005178:integrin binding 0016020:membrane 0055037:recycling endosome 0030336:negative regulation of cell migration 0030036:actin cytoskeleton organization 0008217:regulation of blood pressure 0005829:cytosol 0042802:identical protein binding 0006006:glucose metabolic process 0006915:apoptotic process 0005886:plasma membrane 0005737:cytoplasm 0005654:nucleoplasm 0035091:phosphatidylinositol binding 0016601:Rac protein signal transduction 0015630:microtubule cytoskeleton 0048243:norepinephrine secretion 0019901:protein kinase binding 0005769:early endosome 0043231:intracellular membrane-bounded organelle 0032228:regulation of synaptic transmission, GABAergic 0045171:intercellular bridge
PDB	3P0C
Drugbank	DB09242 ; DB08838 ; DB00697
KEGG	hsa:11188

Type

Detail

Target ID

T53G91

Protein Name

Nischarin

Uniprot ID

Q9Y2I1

Protein Name Alias

Imidazoline receptor 1; I-1; IR1; Imidazoline receptor antisera-selected protein; hIRAS; Imidazoline-1 receptor; I1R; Imidazoline-1 receptor candidate protein; I-1 receptor candidate protein; I1R candidate protein

Gene ID

11188

Gene Symbol

NISCH

Gene Alias

IRAS; KIAA0975

TTD

T78943: Research target

Pfam

PF00787

0005178:integrin binding

0016020:membrane

0055037:recycling endosome

0030336:negative regulation of cell migration

0030036:actin cytoskeleton organization

0008217:regulation of blood pressure

0005829:cytosol

0042802:identical protein binding

0006006:glucose metabolic process

0006915:apoptotic process

0005886:plasma membrane

0005737:cytoplasm

0005654:nucleoplasm

0035091:phosphatidylinositol binding

0016601:Rac protein signal transduction

0015630:microtubule cytoskeleton

0048243:norepinephrine secretion

0019901:protein kinase binding

0005769:early endosome

0043231:intracellular membrane-bounded organelle

0032228:regulation of synaptic transmission, GABAergic

0045171:intercellular bridge

PDB

3P0C

Drugbank

DB09242 ; DB08838 ; DB00697

KEGG

hsa:11188

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0763	Yu Mi Xu	玉米须	Maize style	Zea mays
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H0196	Ma Dou Ling	马兜铃	Slender dutchmanspipe	Aristolochia debilis
H0296	Niu Teng	牛藤	twotooth achyranthes root	Achyranthes bidentata
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H0297	Niu Xi	牛膝	Twotooth achyranthes	Achyranthes bidentata
H1096	Ge Hua	葛花	flower bud of lobed kudzuvine	Pueraria lobata
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0694	Xun Gu Feng	寻骨风	Hairy birthwort	Aristolochia mollissima
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0666	Xiao Mai	小麦	Wheat	Triticum aestivum
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1094	Ge Gen	葛根	Lobed kudzuvine root	Pueraria lobata
H1080	Gan Ge	干葛	Lobed kudzuvine root	Pueraria lobata
H1119	Guang Fang Ji	广防己	Fangchi	Aristolochia fangchi
H1095	Ge Gen Gan Jin Gao	葛根干浸膏	Lobed kudzuvine root	Pueraria lobata
H0748	Chen Xiao Mai Fen	陈小麦粉	Wheat	Triticum aestivum
H0346	Qing Mu Xiang	青木香	Slender dutchmanspipe root	Aristolochia debilis

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 20)