Target Description

Type Detail
Target ID T49CBW
Protein Name Class E basic helix-loop-helix protein 40
Uniprot ID O14503
Protein Name Alias bHLHe40;  Class B basic helix-loop-helix protein 2;  bHLHb2;  Differentially expressed in chondrocytes protein 1;  DEC1;  Enhancer-of-split and hairy-related protein 2;  SHARP-2;  Stimulated by retinoic acid gene 13 protein
Gene ID 8553
Gene Symbol BHLHE40
Gene Alias BHLHB2;  DEC1;  SHARP2;  STRA13
TTD NA
Pfam PF07527 ; PF00010
GO
0005634:nucleus

0006355:regulation of transcription, DNA-templated

0019904:protein domain specific binding

0042752:regulation of circadian rhythm

0045892:negative regulation of transcription, DNA-templated

0005737:cytoplasm

0001102:RNA polymerase II activating transcription factor binding

0032922:circadian regulation of gene expression

0000785:chromatin

0070888:E-box binding

0009952:anterior/posterior pattern specification

0043153:entrainment of circadian clock by photoperiod

0043426:MRF binding

0016604:nuclear body

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0043425:bHLH transcription factor binding

0000122:negative regulation of transcription by RNA polymerase II

0043433:negative regulation of DNA-binding transcription factor activity

0003700:DNA-binding transcription factor activity

0042803:protein homodimerization activity

0006357:regulation of transcription by RNA polymerase II

0046982:protein heterodimerization activity

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

1990837:sequence-specific double-stranded DNA binding

0050767:regulation of neurogenesis

0007623:circadian rhythm

PDB NA
Drugbank NA
KEGG hsa:8553

Related Compounds  (Total: 2)

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C0101
Name: Genistein
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C0456
Name: Tretinoin


Related Herbs  (Total: 45)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H1222 Huai Hua槐花 flower bud of japanese pagodatreeSophora japonica
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H1227 Huai Zhi槐枝 NASophora japonica
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1007 Dou You豆油 Soybean oilGlycine max
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H0533 Teng Ku Shen藤苦参 NASophora flavescens
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0852 Zi Tan紫檀 Burmacoast padaukPterocarpus indicus
H0026 Jiang Soybean pasteGlycine max
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H0979 Di Yu地榆 Garden burnetSanguisorba officinalis
H0906 Ci Wan刺苋 spiny amaranthAmaranthus spinosus
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0575 Tu Ku Shen土苦参 all-grass of hooker wingheadSophora flavescens
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H0792 Zhang Yu章鱼 Common atlantic octopusOctopus vulgaris
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0129 Le Xian Cai勒苋菜 NAAmaranthus spinosus
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1225 Huai Mi槐米 NASophora japonica
H1224 Huai Jiao槐角 pod of japanese pagodatreeSophora japonica
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0980 Di Yu Tan地榆炭 Garden burnetSanguisorba officinalis
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis