HIT-result

Type	Detail
Target ID	T89VFL
Protein Name	Alpha-crystallin B chain
Uniprot ID	P02511
Protein Name Alias	Alpha(B)-crystallin; Heat shock protein beta-5; HspB5; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component
Gene ID	1410
Gene Symbol	CRYAB
Gene Alias	CRYA2; HSPB5
TTD	NA
Pfam	PF00525 ; PF00011
GO	0070062:extracellular exosome 0031430:M band 0006936:muscle contraction 0032991:protein-containing complex 0030018:Z disc 0010941:regulation of cell death 0009986:cell surface 0006457:protein folding 0043066:negative regulation of apoptotic process 0005212:structural constituent of eye lens 0001666:response to hypoxia 0043197:dendritic spine 0071480:cellular response to gamma radiation 1905907:negative regulation of amyloid fibril formation 0042542:response to hydrogen peroxide 0046872:metal ion binding 0005829:cytosol 0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0060561:apoptotic process involved in morphogenesis 0042802:identical protein binding 0030308:negative regulation of cell growth 0044877:protein-containing complex binding 0097060:synaptic membrane 0050821:protein stabilization 0005794:Golgi apparatus 0005654:nucleoplasm 0043204:perikaryon 0032432:actin filament bundle 0032387:negative regulation of intracellular transport 0010259:multicellular organism aging 0002088:lens development in camera-type eye 0005737:cytoplasm 0032355:response to estradiol 0015630:microtubule cytoskeleton 0005739:mitochondrion 2000378:negative regulation of reactive oxygen species metabolic process 0042803:protein homodimerization activity 0005634:nucleus 0051082:unfolded protein binding 0051403:stress-activated MAPK cascade 0031333:negative regulation of protein-containing complex assembly 0007517:muscle organ development 0005198:structural molecule activity 0097512:cardiac myofibril 0045892:negative regulation of transcription, DNA-templated 0014069:postsynaptic density 0007021:tubulin complex assembly 0030424:axon 0008017:microtubule binding 0001540:amyloid-beta binding 1900034:regulation of cellular response to heat 0031109:microtubule polymerization or depolymerization
PDB	2WJ7 ; 5VVV ; 3SGS ; 4M5T ; 2Y1Z ; 3SGP ; 3SGN ; 3SGM ; 4M5S ; 2Y1Y ; 3J07 ; 3SGO ; 3L1G ; 2KLR ; 2N0K ; 2Y22 ; 2YGD ; 6BP9 ; 3SGR
Drugbank	NA
KEGG	hsa:1410

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0031	Jiang Tan	姜炭	Soybean paste	Glycine max
H1225	Huai Mi	槐米	NA	Sophora japonica
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1227	Huai Zhi	槐枝	NA	Sophora japonica
H0111	Ku Shen	苦参	Lightyellow sophora	Sophora flavescens
H0026	Jiang	姜	Soybean paste	Glycine max
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0533	Teng Ku Shen	藤苦参	NA	Sophora flavescens
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1007	Dou You	豆油	Soybean oil	Glycine max
H1174	Hei Da Dou	黑大豆	Black soyabean	Glycine max
H1096	Ge Hua	葛花	flower bud of lobed kudzuvine	Pueraria lobata
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0065	Jin Yin Hua Ti Qu Ye	金银花提取液	Japanese honeysuckle	Lonicera japonica
H0027	Jiang Gao	姜膏	Soybean paste	Glycine max
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0995	Dong Chong Xia Cao	冬虫夏草	Aweto	Cordyceps sinensis
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0370	Ru Xiang	乳香	Olibanum	Boswellia carterii
H1124	Guang Jin Qian Cao	广金钱草	Snowbellleaf tickclover	Desmodium styracifolium
H0852	Zi Tan	紫檀	Burmacoast padauk	Pterocarpus indicus
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H1222	Huai Hua	槐花	flower bud of japanese pagodatree	Sophora japonica
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1094	Ge Gen	葛根	Lobed kudzuvine root	Pueraria lobata
H1080	Gan Ge	干葛	Lobed kudzuvine root	Pueraria lobata
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0354	Ren Dong Teng	忍冬藤	Japanese honeysuckle vine	Lonicera japonica
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1224	Huai Jiao	槐角	pod of japanese pagodatree	Sophora japonica
H1095	Ge Gen Gan Jin Gao	葛根干浸膏	Lobed kudzuvine root	Pueraria lobata
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H0952	Dan Xiang Chi	淡香豉	NA	Glycine max
H0064	Jin Yin Hua	金银花	Japanese honeysuckle	Lonicera japonica
H0792	Zhang Yu	章鱼	Common atlantic octopus	Octopus vulgaris
H0979	Di Yu	地榆	Garden burnet	Sanguisorba officinalis
H1240	Huang Jing Zi	黄荆子	NA	Vitex negundo
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0129	Le Xian Cai	勒苋菜	NA	Amaranthus spinosus
H0035	Bai Su Zi	白苏子	Common perilla fruit	Perilla frutescens
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0906	Ci Wan	刺苋	spiny amaranth	Amaranthus spinosus
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H0980	Di Yu Tan	地榆炭	Garden burnet	Sanguisorba officinalis
H0575	Tu Ku Shen	土苦参	all-grass of hooker winghead	Sophora flavescens
H0944	Dan Dou Gu	淡豆鼓	NA	Glycine max
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 51)