Target Description

Type Detail
Target ID T07TRP
Protein Name Short transient receptor potential channel 5
Uniprot ID Q9UL62
Protein Name Alias TrpC5;  Transient receptor protein 5;  TRP-5;  hTRP-5;  hTRP5
Gene ID 7224
Gene Symbol TRPC5
Gene Alias TRP5
TTD T00156: Clinical Trial target
Pfam PF08344 ; PF12796 ; PF00520
GO
0051117:ATPase binding

0003779:actin binding

0030425:dendrite

0070679:inositol 1,4,5 trisphosphate binding

0030182:neuron differentiation

0006816:calcium ion transport

0007204:positive regulation of cytosolic calcium ion concentration

0050774:negative regulation of dendrite morphogenesis

0007399:nervous system development

0015279:store-operated calcium channel activity

0030276:clathrin binding

0008284:positive regulation of cell population proliferation

0005262:calcium channel activity

0051480:regulation of cytosolic calcium ion concentration

0005737:cytoplasm

0070588:calcium ion transmembrane transport

0034704:calcium channel complex

0005887:integral component of plasma membrane

1902630:regulation of membrane hyperpolarization

0005886:plasma membrane

0045121:membrane raft

0042805:actinin binding

0034703:cation channel complex

0006828:manganese ion transport

0070782:phosphatidylserine exposure on apoptotic cell surface

0045666:positive regulation of neuron differentiation

0051402:neuron apoptotic process

0010800:positive regulation of peptidyl-threonine phosphorylation

0045773:positive regulation of axon extension

0043025:neuronal cell body

0030426:growth cone

PDB 6YSN
Drugbank NA
KEGG hsa:7224

Related Compounds  (Total: 3)

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C0089
Name: Galangin
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C0101
Name: Genistein
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C0325
Name: Progesterone


Related Herbs  (Total: 64)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H1225 Huai Mi槐米 NASophora japonica
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1227 Huai Zhi槐枝 NASophora japonica
H0111 Ku Shen苦参 Lightyellow sophoraSophora flavescens
H0026 Jiang Soybean pasteGlycine max
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0053 Jin Lian Hua金莲花 Chinese globeflowerTrollius chinensis
H0951 Dan Shen Jin Gao丹参浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0533 Teng Ku Shen藤苦参 NASophora flavescens
H1007 Dou You豆油 Soybean oilGlycine max
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H0092 Ju Hua菊花 Florists chrysanthemum flowerChrysanthemum morifolium
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H1183 Hong Dou红豆 Hosie ormosiaOrmosia hosiei
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0582 Cao Dou Kou Ren草豆蔻仁 Katsumada galangalAlpinia katsumadai
H0142 Liang Jiang良姜 NAAlpinia officinarum
H0575 Tu Ku Shen土苦参 all-grass of hooker wingheadSophora flavescens
H0995 Dong Chong Xia Cao冬虫夏草 AwetoCordyceps sinensis
H0574 Cao Dou Kou草豆蔻 Katsumada galangalAlpinia katsumadai
H0950 Dan Shen Gan Jin Gao丹参干浸膏 The root of red-rooted salviaSalvia miltiorrhiza
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H0852 Zi Tan紫檀 Burmacoast padaukPterocarpus indicus
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H1140 Guo Gang Long过岗龙 NAEntada phaseoloides
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H1093 Gao Liang Jiang You高良姜油 Lesser galangalAlpinia officinarum
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1222 Huai Hua槐花 flower bud of japanese pagodatreeSophora japonica
H1141 Guo Gang Long Jin Gao过岗龙浸膏 NAEntada phaseoloides
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1224 Huai Jiao槐角 pod of japanese pagodatreeSophora japonica
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H0949 Dan Shen丹参 The root of red-rooted salviaSalvia miltiorrhiza
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0792 Zhang Yu章鱼 Common atlantic octopusOctopus vulgaris
H0979 Di Yu地榆 Garden burnetSanguisorba officinalis
H0457 Shi Er石耳 Rock-EarsUmbilicaria esculenta
H1240 Huang Jing Zi黄荆子 NAVitex negundo
H1161 Hang Ju杭菊 Chrysanthemum flowerChrysanthemum morifolium
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0129 Le Xian Cai勒苋菜 NAAmaranthus spinosus
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0906 Ci Wan刺苋 spiny amaranthAmaranthus spinosus
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H1092 Gao Liang Jiang高良姜 Lesser galangalAlpinia officinarum
H0980 Di Yu Tan地榆炭 Garden burnetSanguisorba officinalis
H0219 Man Shan Hong满山红 Dahurian rhododendronRhododendron dauricum
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis