HIT-result

ID: C0089	Common name: Galangin
IUPAC: 3,5,7-trihydroxy-2-phenylchromen-4-one	CAS: CAS:548-83-4
Chembl ID: CHEMBL309490	Pubchem ID: CID:5281616
Formula: C15H10O5	TCM-ID: TCMC1201
Smiles: C1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
Alias: Flavone, 3,5,7-trihydroxy-; Galangin; 3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one; 3,5,7-Trihydroxyflavone; NSC 407229; Norizalpinin	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T84W8G	Aryl hydrocarbon receptor	AHR	P35869	A	3 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	A	1 Reference(s)
T07TRP	Short transient receptor potential channel 5	TRPC5	Q9UL62	A	1 Reference(s)
T02O3F	Endothelial lipase	LIPG	Q9Y5X9	A	1 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	A	1 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	B	1 Reference(s)
T07TMB	Cyclin-dependent kinase 1	CDK1	P06493	B	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	B	1 Reference(s)
T46AQJ	Glutathione S-transferase P	GSTP1	P09211	B	1 Reference(s)
T95QJ9	G1/S-specific cyclin-D3	CCND3	P30281	B	1 Reference(s)
T98RXH	Focal adhesion kinase 1	PTK2	Q05397	B	1 Reference(s)
T91D6X	Protein Wnt-3a	WNT3A	P56704	B	1 Reference(s)
T61SU2	Coxsackievirus and adenovirus receptor	CXADR	P78310	B	1 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	C	1 Reference(s)
T04NYZ	Disintegrin and metalloproteinase domain-containing protein 9	ADAM9	Q13443	C	1 Reference(s)
T26CFB	DNA damage-inducible transcript 3 protein	DDIT3	P35638;P0DPQ6	C	1 Reference(s)
T94H37	Cadherin-1	CDH1	P12830	C	1 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	C	1 Reference(s)
T09KPZ	Vimentin	VIM	P08670	C	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0219	Man Shan Hong	满山红	Dahurian rhododendron	Rhododendron dauricum
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1161	Hang Ju	杭菊	Chrysanthemum flower	Chrysanthemum morifolium
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0457	Shi Er	石耳	Rock-Ears	Umbilicaria esculenta
H1093	Gao Liang Jiang You	高良姜油	Lesser galangal	Alpinia officinarum
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1183	Hong Dou	红豆	Hosie ormosia	Ormosia hosiei
H0142	Liang Jiang	良姜	NA	Alpinia officinarum
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0574	Cao Dou Kou	草豆蔻	Katsumada galangal	Alpinia katsumadai
H0053	Jin Lian Hua	金莲花	Chinese globeflower	Trollius chinensis
H0092	Ju Hua	菊花	Florists chrysanthemum flower	Chrysanthemum morifolium
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H0582	Cao Dou Kou Ren	草豆蔻仁	Katsumada galangal	Alpinia katsumadai
H1141	Guo Gang Long Jin Gao	过岗龙浸膏	NA	Entada phaseoloides
H1140	Guo Gang Long	过岗龙	NA	Entada phaseoloides
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1092	Gao Liang Jiang	高良姜	Lesser galangal	Alpinia officinarum
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis

Compound Description

Related Targets (Total: 19)

Related Herbs (Total: 25)