Target Description
| Type | Detail |
|---|---|
| Target ID | T17X6I |
| Protein Name | DNA fragmentation factor subunit alpha |
| Uniprot ID |
O00273 |
| Protein Name Alias | DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD |
| Gene ID |
1676 |
| Gene Symbol | DFFA |
| Gene Alias | DFF1; DFF45 |
| TTD | T38745: Research target |
| Pfam | PF09033 ; PF02017 |
| GO |
0005654:nucleoplasm
0032991:protein-containing complex 0019904:protein domain specific binding 1902511:negative regulation of apoptotic DNA fragmentation 0032076:negative regulation of deoxyribonuclease activity 0005829:cytosol 0042981:regulation of apoptotic process 0061077:chaperone-mediated protein folding 0070242:thymocyte apoptotic process 0043065:positive regulation of apoptotic process 0060703:deoxyribonuclease inhibitor activity 1900118:negative regulation of execution phase of apoptosis 0006309:apoptotic DNA fragmentation 0044183:protein folding chaperone 0000785:chromatin 0005886:plasma membrane 0005634:nucleus |
| PDB | 1IBX ; 1KOY ; 1IYR |
| Drugbank | NA |
| KEGG | hsa:1676 |
Related Herbs (Total: 45)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0111 | Ku Shen | 苦参 | Lightyellow sophora | Sophora flavescens |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1080 | Gan Ge | 干葛 | Lobed kudzuvine root | Pueraria lobata |
| H0852 | Zi Tan | 紫檀 | Burmacoast padauk | Pterocarpus indicus |
| H0995 | Dong Chong Xia Cao | 冬虫夏草 | Aweto | Cordyceps sinensis |
| H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1174 | Hei Da Dou | 黑大豆 | Black soyabean | Glycine max |
| H0980 | Di Yu Tan | 地榆炭 | Garden burnet | Sanguisorba officinalis |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1124 | Guang Jin Qian Cao | 广金钱草 | Snowbellleaf tickclover | Desmodium styracifolium |
| H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
| H0952 | Dan Xiang Chi | 淡香豉 | NA | Glycine max |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0026 | Jiang | 姜 | Soybean paste | Glycine max |
| H1095 | Ge Gen Gan Jin Gao | 葛根干浸膏 | Lobed kudzuvine root | Pueraria lobata |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0575 | Tu Ku Shen | 土苦参 | all-grass of hooker winghead | Sophora flavescens |
| H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
| H0129 | Le Xian Cai | 勒苋菜 | NA | Amaranthus spinosus |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0979 | Di Yu | 地榆 | Garden burnet | Sanguisorba officinalis |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0792 | Zhang Yu | 章鱼 | Common atlantic octopus | Octopus vulgaris |
| H1094 | Ge Gen | 葛根 | Lobed kudzuvine root | Pueraria lobata |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0906 | Ci Wan | 刺苋 | spiny amaranth | Amaranthus spinosus |
| H0944 | Dan Dou Gu | 淡豆鼓 | NA | Glycine max |
| H0027 | Jiang Gao | 姜膏 | Soybean paste | Glycine max |
| H0031 | Jiang Tan | 姜炭 | Soybean paste | Glycine max |
| H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
| H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1096 | Ge Hua | 葛花 | flower bud of lobed kudzuvine | Pueraria lobata |
| H0533 | Teng Ku Shen | 藤苦参 | NA | Sophora flavescens |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
| H1007 | Dou You | 豆油 | Soybean oil | Glycine max |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |