Target Description

Type Detail
Target ID T89A2U
Protein Name Hsp90 co-chaperone Cdc37
Uniprot ID Q16543
Protein Name Alias Hsp90 chaperone protein kinase-targeting subunit;  p50Cdc37
Gene ID 11140
Gene Symbol CDC37
Gene Alias CDC37A
TTD T94366: Research target
Pfam PF08565 ; PF08564 ; PF03234
GO
0070062:extracellular exosome

0060544:regulation of necroptotic process

0098779:positive regulation of mitophagy in response to mitochondrial depolarization

0006457:protein folding

0051087:chaperone binding

0060334:regulation of interferon-gamma-mediated signaling pathway

0031072:heat shock protein binding

0060338:regulation of type I interferon-mediated signaling pathway

0038128:ERBB2 signaling pathway

0005829:cytosol

0101031:chaperone complex

0050821:protein stabilization

0097110:scaffold protein binding

0019887:protein kinase regulator activity

0005737:cytoplasm

0019900:kinase binding

0006605:protein targeting

0000079:regulation of cyclin-dependent protein serine/threonine kinase activity

0019901:protein kinase binding

0051082:unfolded protein binding

0051879:Hsp90 protein binding

1990565:HSP90-CDC37 chaperone complex

0010608:posttranscriptional regulation of gene expression

PDB 5FWP ; 5FWL ; 2N5X ; 2NCA ; 1US7 ; 5HPE ; 5FWM ; 5FWK ; 2K5B ; 2W0G
Drugbank NA
KEGG hsa:11140

Related Compounds  (Total: 1)

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C1260
Name: Coumestrol


Related Herbs  (Total: 17)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0027 Jiang Gao姜膏 Soybean pasteGlycine max
H1080 Gan Ge干葛 Lobed kudzuvine rootPueraria lobata
H0944 Dan Dou Gu淡豆鼓 NAGlycine max
H0952 Dan Xiang Chi淡香豉 NAGlycine max
H0516 Suan Zao酸枣 Spine dateZiziphus jujuba var. spinosa
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0781 Zao Ren枣仁 seed of spine dateZiziphus jujuba var. spinosa
H1094 Ge Gen葛根 Lobed kudzuvine rootPueraria lobata
H1095 Ge Gen Gan Jin Gao葛根干浸膏 Lobed kudzuvine rootPueraria lobata
H1096 Ge Hua葛花 flower bud of lobed kudzuvinePueraria lobata
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0517 Suan Zao Ren酸枣仁 Spine date seedZiziphus jujuba var. spinosa
H1174 Hei Da Dou黑大豆 Black soyabeanGlycine max
H1007 Dou You豆油 Soybean oilGlycine max
H0026 Jiang Soybean pasteGlycine max
H0031 Jiang Tan姜炭 Soybean pasteGlycine max
H0941 Da Zao大枣 Chinese dateZiziphus jujuba