Compound Description
| ID: C1260 | Common name: Coumestrol |
| IUPAC: 3,9-dihydroxy-[1]benzofuro[3,2-c]chromen-6-one | CAS: CAS:479-13-0 |
| Chembl ID: CHEMBL30707 | Pubchem ID: CID:5281707 |
| Formula: C15H8O5 | TCM-ID: TCMC950 |
| Smiles: C1=CC2=C(C=C1O)OC3=C2C(=O)OC4=C3C=CC(=C4)O | |
| Alias:
3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, δ-lactone;
3,9-Dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one; 2-(2,4-Dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylic acid δ-lactone; Coumesterol; Coumestrol; Cumoestrol; Cumostrol; NSC 22842 |
Structure:
|
Related Targets (Total: 5)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
A | 1 Reference(s) |
| T05O6O | Estrogen receptor beta | ESR2 |
Q92731 |
B | 1 Reference(s) |
| T89A2U | Hsp90 co-chaperone Cdc37 | CDC37 |
Q16543 |
C | 1 Reference(s) |
| T91AIW | Receptor-type tyrosine-protein kinase FLT3 | FLT3 |
P36888 |
C | 1 Reference(s) |
| T95K8Q | Intestinal-type alkaline phosphatase | ALPI |
P09923 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 17)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1007 | Dou You | 豆油 | Soybean oil | Glycine max |
| H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
| H0517 | Suan Zao Ren | 酸枣仁 | Spine date seed | Ziziphus jujuba var. spinosa |
| H0026 | Jiang | 姜 | Soybean paste | Glycine max |
| H1094 | Ge Gen | 葛根 | Lobed kudzuvine root | Pueraria lobata |
| H0952 | Dan Xiang Chi | 淡香豉 | NA | Glycine max |
| H0027 | Jiang Gao | 姜膏 | Soybean paste | Glycine max |
| H0516 | Suan Zao | 酸枣 | Spine date | Ziziphus jujuba var. spinosa |
| H1096 | Ge Hua | 葛花 | flower bud of lobed kudzuvine | Pueraria lobata |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0031 | Jiang Tan | 姜炭 | Soybean paste | Glycine max |
| H1080 | Gan Ge | 干葛 | Lobed kudzuvine root | Pueraria lobata |
| H1174 | Hei Da Dou | 黑大豆 | Black soyabean | Glycine max |
| H1095 | Ge Gen Gan Jin Gao | 葛根干浸膏 | Lobed kudzuvine root | Pueraria lobata |
| H0781 | Zao Ren | 枣仁 | seed of spine date | Ziziphus jujuba var. spinosa |
| H0944 | Dan Dou Gu | 淡豆鼓 | NA | Glycine max |
Ckey description of the interaction between compound and target