Compound Description
| ID: C0086 | Common name: Fumaric Acid |
| IUPAC: (E)-but-2-enedioic acid | CAS: CAS:110-17-8 |
| Chembl ID: CHEMBL503160 | Pubchem ID: CID:444972 |
| Formula: C4H4O4 | TCM-ID: TCMC1194 |
| Smiles: OC(=O)/C=C/C(=O)O | |
| Alias:
2-Butenedioic acid (E)-;
Fumaric acid; (2E)-2-Butenedioic acid; (2E)-But-2-enedioic acid; (2E)-But-2-enedioic acid; (E)-2-Butenedioic acid; 2-(E)-Butenedioic acid; 2-Butenedioic acid, (E)-; Allomaleic acid; Bakeshure 451; Bakeshure 470; Boletic acid; FC 33; FC 33 (acid); Fumarates; Lichenic acid; NSC 2752; Petrom; trans-1,2-Ethylenedicarboxylic acid; trans-2-Butenedioic acid; trans-Butenedioic acid |
Structure:
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Related Targets (Total: 3)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
B | 1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
C | 1 Reference(s) |
| T73QZ2 | Methylcytosine dioxygenase TET2 | TET2 |
Q6N021 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 38)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0612 | Cao Shan Hu Jin Gao | 草珊瑚浸膏 | NA | Sarcandra glabra |
| H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
| H1184 | Bai Lian | 白蔹 | Japanese ampelopsis | Ampelopsis japonica |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0706 | Yan Hu Suo | 延胡索 | Yanhusuo | Corydalis yanhusuo |
| H0757 | Ying Su Ke | 罂粟壳 | Opium poppy pericarp | Papaver somniferum |
| H0714 | Yan Tai Chai Hu | 烟台柴胡 | Chinese thorowax | Bupleurum chinense |
| H1088 | Gan Zhe | 甘蔗 | Sweetcane culm | Saccharum sinensis |
| H0115 | Kuan Dong Hua | 款冬花 | Common coltsfoot | Tussilago farfara |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0659 | Chai Hu Jin Gao | 柴胡浸膏 | Chinese thorowax | Bupleurum chinense |
| H0650 | Chai Hu | 柴胡 | Chinese thorowax | Bupleurum chinense |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0595 | Wu Hua Guo | 无花果 | Fig | Ficus carica |
| H0248 | Mi Ying Su Ke | 蜜罂粟壳 | Opium poppy | Papaver somniferum |
| H0756 | Ying Su | 罂粟 | Opium poppy | Papaver somniferum |
| H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0290 | Niu Er Feng | 牛耳枫 | calyx-shaped daphniphyllum fruit | Daphniphyllum calycinum |
| H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
| H0498 | Si Ji Cai | 四季菜 | Ghostplant wormwood | Artemisia lactiflora |
| H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H1110 | Gua Lou Zi | 瓜蒌子 | mongolian snakegourd seed | Trichosanthes kirilowii maxim |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0665 | Chai Hu Shao | 柴胡梢 | Chinese thorowax | Bupleurum chinense |
| H0243 | Mi Kuan Dong Hua | 蜜款冬花 | Common coltsfoot | Tussilago farfara |
| H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
| H0083 | Jiu Jie Cha | 九节茶 | Glabrous sarcandra | Sarcandra glabra |
| H0961 | Dang Yao | 当药 | Chinese swertia | Swertia chinensis |
| H0766 | Yu Zhu | 玉竹 | NA | Polygonatum odoratum |
| H0903 | Ci Cai | 荠菜 | Shepherdspurse | Capsella bursa-pastoris |
| H0696 | Ya Jiao Ai | 鸭脚艾 | Ghostplant wormwood | Artemisia lactiflora |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
Ckey description of the interaction between compound and target